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Items: 1 to 20 of 110

1.

RACK1 modulates NF-κB activation by interfering with the interaction between TRAF2 and the IKK complex.

Yao F, Long LY, Deng YZ, Feng YY, Ying GY, Bao WD, Li G, Guan DX, Zhu YQ, Li JJ, Xie D.

Cell Res. 2014 Mar;24(3):359-71. doi: 10.1038/cr.2013.162. Epub 2013 Dec 10.

2.

Tumor necrosis factor (TNF) receptor-associated factor (TRAF)-interacting protein (TRIP) negatively regulates the TRAF2 ubiquitin-dependent pathway by suppressing the TRAF2-sphingosine 1-phosphate (S1P) interaction.

Park ES, Choi S, Shin B, Yu J, Yu J, Hwang JM, Yun H, Chung YH, Choi JS, Choi Y, Rho J.

J Biol Chem. 2015 Apr 10;290(15):9660-73. doi: 10.1074/jbc.M114.609685. Epub 2015 Feb 25.

3.

PKC phosphorylation of TRAF2 mediates IKKalpha/beta recruitment and K63-linked polyubiquitination.

Li S, Wang L, Dorf ME.

Mol Cell. 2009 Jan 16;33(1):30-42. doi: 10.1016/j.molcel.2008.11.023.

4.

TRAF2 phosphorylation modulates tumor necrosis factor alpha-induced gene expression and cell resistance to apoptosis.

Blackwell K, Zhang L, Thomas GS, Sun S, Nakano H, Habelhah H.

Mol Cell Biol. 2009 Jan;29(2):303-14. doi: 10.1128/MCB.00699-08. Epub 2008 Nov 3.

5.

TRAF2 phosphorylation promotes NF-κB-dependent gene expression and inhibits oxidative stress-induced cell death.

Zhang L, Blackwell K, Altaeva A, Shi Z, Habelhah H.

Mol Biol Cell. 2011 Jan 1;22(1):128-40. doi: 10.1091/mbc.E10-06-0556. Epub 2010 Nov 30.

6.

Interaction of the TNFR-receptor associated factor TRAF1 with I-kappa B kinase-2 and TRAF2 indicates a regulatory function for NF-kappa B signaling.

Sughra K, Birbach A, de Martin R, Schmid JA.

PLoS One. 2010 Sep 13;5(9):e12683. doi: 10.1371/journal.pone.0012683.

7.

Sphingosine-1-phosphate is a missing cofactor for the E3 ubiquitin ligase TRAF2.

Alvarez SE, Harikumar KB, Hait NC, Allegood J, Strub GM, Kim EY, Maceyka M, Jiang H, Luo C, Kordula T, Milstien S, Spiegel S.

Nature. 2010 Jun 24;465(7301):1084-8. doi: 10.1038/nature09128.

9.

IFIT5 positively regulates NF-κB signaling through synergizing the recruitment of IκB kinase (IKK) to TGF-β-activated kinase 1 (TAK1).

Zheng C, Zheng Z, Zhang Z, Meng J, Liu Y, Ke X, Hu Q, Wang H.

Cell Signal. 2015 Dec;27(12):2343-54. doi: 10.1016/j.cellsig.2015.08.018. Epub 2015 Sep 1.

PMID:
26334375
11.

TRAF2 suppresses basal IKK activity in resting cells and TNFalpha can activate IKK in TRAF2 and TRAF5 double knockout cells.

Zhang L, Blackwell K, Thomas GS, Sun S, Yeh WC, Habelhah H.

J Mol Biol. 2009 Jun 12;389(3):495-510. doi: 10.1016/j.jmb.2009.04.054. Epub 2009 May 3.

12.

Verproside inhibits TNF-α-induced MUC5AC expression through suppression of the TNF-α/NF-κB pathway in human airway epithelial cells.

Lee SU, Sung MH, Ryu HW, Lee J, Kim HS, In HJ, Ahn KS, Lee HJ, Lee HK, Shin DH, Lee Y, Hong ST, Oh SR.

Cytokine. 2016 Jan;77:168-75. doi: 10.1016/j.cyto.2015.08.262. Epub 2015 Aug 28.

PMID:
26318254
13.

Desflurane preconditioning inhibits endothelial nuclear factor-kappa-B activation by targeting the proximal end of tumor necrosis factor-alpha signaling.

Li Y, Zhang X, Zhu B, Xue Z.

Anesth Analg. 2008 May;106(5):1473-9, table of contents. doi: 10.1213/ane.0b013e318168b3f2.

PMID:
18420862
14.

Regulation and function of IKK and IKK-related kinases.

Häcker H, Karin M.

Sci STKE. 2006 Oct 17;2006(357):re13. Review.

PMID:
17047224
15.

Classical NF-κB activation impairs skeletal muscle oxidative phenotype by reducing IKK-α expression.

Remels AH, Gosker HR, Langen RC, Polkey M, Sliwinski P, Galdiz J, van den Borst B, Pansters NA, Schols AM.

Biochim Biophys Acta. 2014 Feb;1842(2):175-85. doi: 10.1016/j.bbadis.2013.11.001. Epub 2013 Nov 8.

16.

GbetaL regulates TNFalpha-induced NF-kappaB signaling by directly inhibiting the activation of IkappaB kinase.

Kim YL, Kim JE, Shin KJ, Lee S, Ahn C, Chung J, Kim DH, Seong JY, Hwang JI.

Cell Signal. 2008 Nov;20(11):2127-33. doi: 10.1016/j.cellsig.2008.08.001. Epub 2008 Aug 9.

PMID:
18755269
17.

IRF-1 inhibits NF-κB activity, suppresses TRAF2 and cIAP1 and induces breast cancer cell specific growth inhibition.

Armstrong MJ, Stang MT, Liu Y, Yan J, Pizzoferrato E, Yim JH.

Cancer Biol Ther. 2015;16(7):1029-41. doi: 10.1080/15384047.2015.1046646.

18.
19.

Phosphorylation of TRAF2 within its RING domain inhibits stress-induced cell death by promoting IKK and suppressing JNK activation.

Thomas GS, Zhang L, Blackwell K, Habelhah H.

Cancer Res. 2009 Apr 15;69(8):3665-72. doi: 10.1158/0008-5472.CAN-08-4867. Epub 2009 Mar 31.

20.

Tumor necrosis factor-alpha-induced IKK phosphorylation of NF-kappaB p65 on serine 536 is mediated through the TRAF2, TRAF5, and TAK1 signaling pathway.

Sakurai H, Suzuki S, Kawasaki N, Nakano H, Okazaki T, Chino A, Doi T, Saiki I.

J Biol Chem. 2003 Sep 19;278(38):36916-23. Epub 2003 Jul 3.

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