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Tax posttranslational modifications and interaction with calreticulin in MT-2 cells and human peripheral blood mononuclear cells of human T cell lymphotropic virus type-I-associated myelopathy/tropical spastic paraparesis patients.

Medina F, Quintremil S, Alberti C, Barriga A, Cartier L, Puente J, Ramírez E, Ferreira A, Tanaka Y, Valenzuela MA.

AIDS Res Hum Retroviruses. 2014 Apr;30(4):370-9. doi: 10.1089/AID.2013.0036. Epub 2014 Jan 24.


Tax secretion from peripheral blood mononuclear cells and Tax detection in plasma of patients with human T-lymphotropic virus-type 1-associated myelopathy/tropical spastic paraparesis and asymptomatic carriers.

Medina F, Quintremil S, Alberti C, Godoy F, Pando ME, Bustamante A, Barriga A, Cartier L, Puente J, Tanaka Y, Valenzuela MA, Ramírez E.

J Med Virol. 2016 Mar;88(3):521-31. doi: 10.1002/jmv.24342. Epub 2015 Oct 19.


Interaction of HTLV-1 Tax protein with calreticulin: implications for Tax nuclear export and secretion.

Alefantis T, Flaig KE, Wigdahl B, Jain P.

Biomed Pharmacother. 2007 May;61(4):194-200. Epub 2007 Mar 9.


Tax and Semaphorin 4D Released from Lymphocytes Infected with Human Lymphotropic Virus Type 1 and Their Effect on Neurite Growth.

Quintremil S, Alberti C, Rivera M, Medina F, Puente J, Cartier L, Ramírez E, Tanaka Y, Valenzuela MA.

AIDS Res Hum Retroviruses. 2016 Jan;32(1):68-79. doi: 10.1089/aid.2015.0008. Epub 2015 Sep 21.


Detection of human T-lymphotropic virus type I p40tax protein in cerebrospinal fluid cells from patients with human T-lymphotropic virus type I-associated myelopathy/tropical spastic paraparesis.

Moritoyo T, Izumo S, Moritoyo H, Tanaka Y, Kiyomatsu Y, Nagai M, Usuku K, Sorimachi M, Osame M.

J Neurovirol. 1999 Jun;5(3):241-8.


Cytoplasmic Localization of HTLV-1 HBZ Protein: A Biomarker of HTLV-1-Associated Myelopathy/Tropical Spastic Paraparesis (HAM/TSP).

Baratella M, Forlani G, Raval GU, Tedeschi A, Gout O, Gessain A, Tosi G, Accolla RS.

PLoS Negl Trop Dis. 2017 Jan 17;11(1):e0005285. doi: 10.1371/journal.pntd.0005285. eCollection 2017 Jan.


In vivo expression of the HBZ gene of HTLV-1 correlates with proviral load, inflammatory markers and disease severity in HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP).

Saito M, Matsuzaki T, Satou Y, Yasunaga J, Saito K, Arimura K, Matsuoka M, Ohara Y.

Retrovirology. 2009 Feb 19;6:19. doi: 10.1186/1742-4690-6-19.


Correlation of human T-cell lymphotropic virus type 1 (HTLV-1) mRNA with proviral DNA load, virus-specific CD8(+) T cells, and disease severity in HTLV-1-associated myelopathy (HAM/TSP).

Yamano Y, Nagai M, Brennan M, Mora CA, Soldan SS, Tomaru U, Takenouchi N, Izumo S, Osame M, Jacobson S.

Blood. 2002 Jan 1;99(1):88-94.


Molecular and clinical effects of betamethasone in human T-cell lymphotropic virus type-I-associated myelopathy/tropical spastic paraparesis patients.

Alberti C, Cartier L, Valenzuela MA, Puente J, Tanaka Y, Ramirez E.

J Med Virol. 2011 Sep;83(9):1641-9. doi: 10.1002/jmv.22131.


Anti-Tax antibody levels in asymptomatic carriers, oligosymptomatic carriers, patients with rheumatologic disease or with HAM/TSP do not correlate with HTLV-1 proviral load.

de Souza JG, da Fonseca FG, Martins ML, Martins CP, de Carvalho LD, Coelho-dos-Reis JG, Carneiro-Proietti AB, Martins-Filho OA, Barbosa-Stancioli EF; GIPH.

J Clin Virol. 2011 Jan;50(1):13-8. doi: 10.1016/j.jcv.2010.09.007. Epub 2010 Oct 15.


Functional impairment of Tax-specific but not cytomegalovirus-specific CD8+ T lymphocytes in a minor population of asymptomatic human T-cell leukemia virus type 1-carriers.

Takamori A, Hasegawa A, Utsunomiya A, Maeda Y, Yamano Y, Masuda M, Shimizu Y, Tamai Y, Sasada A, Zeng N, Choi I, Uike N, Okamura J, Watanabe T, Masuda T, Kannagi M.

Retrovirology. 2011 Dec 7;8:100. doi: 10.1186/1742-4690-8-100.


Increased HTLV type 1 tax specific CD8+ cells in HTLV type 1-asociated myelopathy/tropical spastic paraparesis: correlation with HTLV type 1 proviral load.

Kubota R, Nagai M, Kawanishi T, Osame M, Jacobson S.

AIDS Res Hum Retroviruses. 2000 Nov 1;16(16):1705-9.


Human T cell lymphotropic virus type I (HTLV-I)-specific CD4+ T cells: immunodominance hierarchy and preferential infection with HTLV-I.

Goon PK, Igakura T, Hanon E, Mosley AJ, Barfield A, Barnard AL, Kaftantzi L, Tanaka Y, Taylor GP, Weber JN, Bangham CR.

J Immunol. 2004 Feb 1;172(3):1735-43.

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