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Items: 1 to 20 of 41


Helping Eve overcome ADAM: G-quadruplexes in the ADAM-15 promoter as new molecular targets for breast cancer therapeutics.

Brown RV, Gaerig VC, Simmons T, Brooks TA.

Molecules. 2013 Dec 5;18(12):15019-34. doi: 10.3390/molecules181215019.


Identification and characterization of a new G-quadruplex forming region within the kRAS promoter as a transcriptional regulator.

Morgan RK, Batra H, Gaerig VC, Hockings J, Brooks TA.

Biochim Biophys Acta. 2016 Feb;1859(2):235-45. doi: 10.1016/j.bbagrm.2015.11.004. Epub 2015 Nov 18.


Yin Yang 1 contains G-quadruplex structures in its promoter and 5'-UTR and its expression is modulated by G4 resolvase 1.

Huang W, Smaldino PJ, Zhang Q, Miller LD, Cao P, Stadelman K, Wan M, Giri B, Lei M, Nagamine Y, Vaughn JP, Akman SA, Sui G.

Nucleic Acids Res. 2012 Feb;40(3):1033-49. doi: 10.1093/nar/gkr849. Epub 2011 Oct 12.


The major G-quadruplex formed in the human platelet-derived growth factor receptor β promoter adopts a novel broken-strand structure in K+ solution.

Chen Y, Agrawal P, Brown RV, Hatzakis E, Hurley L, Yang D.

J Am Chem Soc. 2012 Aug 15;134(32):13220-3. doi: 10.1021/ja305764d. Epub 2012 Aug 6.


G-quadruplex formation within the promoter of the KRAS proto-oncogene and its effect on transcription.

Cogoi S, Xodo LE.

Nucleic Acids Res. 2006 May 10;34(9):2536-49. Print 2006.


c-MYC promoter G-quadruplex formed at the 5'-end of NHE III1 element: insights into biological relevance and parallel-stranded G-quadruplex stability.

Mathad RI, Hatzakis E, Dai J, Yang D.

Nucleic Acids Res. 2011 Nov 1;39(20):9023-33. doi: 10.1093/nar/gkr612. Epub 2011 Jul 27.


Solution structure of all parallel G-quadruplex formed by the oncogene RET promoter sequence.

Tong X, Lan W, Zhang X, Wu H, Liu M, Cao C.

Nucleic Acids Res. 2011 Aug;39(15):6753-63. doi: 10.1093/nar/gkr233. Epub 2011 May 2.


High-affinity homologous peptide nucleic acid probes for targeting a quadruplex-forming sequence from a MYC promoter element.

Roy S, Tanious FA, Wilson WD, Ly DH, Armitage BA.

Biochemistry. 2007 Sep 18;46(37):10433-43. Epub 2007 Aug 24.


Epigenetic regulation by Z-DNA silencer function controls cancer-associated ADAM-12 expression in breast cancer: cross-talk between MeCP2 and NF1 transcription factor family.

Ray BK, Dhar S, Henry C, Rich A, Ray A.

Cancer Res. 2013 Jan 15;73(2):736-44. doi: 10.1158/0008-5472.CAN-12-2601. Epub 2012 Nov 7.


Spontaneous DNA lesions modulate DNA structural transitions occurring at nuclease hypersensitive element III(1) of the human c-myc proto-oncogene.

Beckett J, Burns J, Broxson C, Tornaletti S.

Biochemistry. 2012 Jul 3;51(26):5257-68. Epub 2012 Jun 19.


The ectodomain shedding of E-cadherin by ADAM15 supports ErbB receptor activation.

Najy AJ, Day KC, Day ML.

J Biol Chem. 2008 Jun 27;283(26):18393-401. doi: 10.1074/jbc.M801329200. Epub 2008 Apr 22.


Selective recognition of oncogene promoter G-quadruplexes by Mg2+.

Yan YY, Lin J, Ou TM, Tan JH, Li D, Gu LQ, Huang ZS.

Biochem Biophys Res Commun. 2010 Nov 26;402(4):614-8. doi: 10.1016/j.bbrc.2010.10.065. Epub 2010 Oct 29.


Spectroscopy probing of the formation, recognition, and conversion of a G-quadruplex in the promoter region of the bcl-2 oncogene.

Li H, Liu Y, Lin S, Yuan G.

Chemistry. 2009;15(10):2445-52. doi: 10.1002/chem.200801922.


A novel G-quadruplex-forming GGA repeat region in the c-myb promoter is a critical regulator of promoter activity.

Palumbo SL, Memmott RM, Uribe DJ, Krotova-Khan Y, Hurley LH, Ebbinghaus SW.

Nucleic Acids Res. 2008 Apr;36(6):1755-69. doi: 10.1093/nar/gkm1069. Epub 2008 Feb 5.


Nucleic acid clamp-mediated recognition and stabilization of the physiologically relevant MYC promoter G-quadruplex.

Hao T, Gaerig VC, Brooks TA.

Nucleic Acids Res. 2016 Dec 15;44(22):11013-11023. Epub 2016 Oct 26.


Evidence of genome-wide G4 DNA-mediated gene expression in human cancer cells.

Verma A, Yadav VK, Basundra R, Kumar A, Chowdhury S.

Nucleic Acids Res. 2009 Jul;37(13):4194-204. doi: 10.1093/nar/gkn1076. Epub 2009 Feb 11.


Role of ADAM-9 disintegrin-cysteine-rich domains in human keratinocyte migration.

Zigrino P, Steiger J, Fox JW, Löffek S, Schild A, Nischt R, Mauch C.

J Biol Chem. 2007 Oct 19;282(42):30785-93. Epub 2007 Aug 17.

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