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Items: 1 to 20 of 92

1.

Hypoxia reduces the efficiency of elisidepsin by inhibiting hydroxylation and altering the structure of lipid rafts.

Király A, Váradi T, Hajdu T, Rühl R, Galmarini CM, Szöllősi J, Nagy P.

Mar Drugs. 2013 Dec 2;11(12):4858-75. doi: 10.3390/md11124858.

2.

ErbB protein modifications are secondary to severe cell membrane alterations induced by elisidepsin treatment.

Váradi T, Roszik J, Lisboa D, Vereb G, Molina-Guijarro JM, Galmarini CM, Szöllosi J, Nagy P.

Eur J Pharmacol. 2011 Sep 30;667(1-3):91-9. doi: 10.1016/j.ejphar.2011.05.064. Epub 2011 Jun 2.

PMID:
21658382
3.

Elisidepsin Interacts Directly with Glycosylceramides in the Plasma Membrane of Tumor Cells to Induce Necrotic Cell Death.

Molina-Guijarro JM, García C, Macías Á, García-Fernández LF, Moreno C, Reyes F, Martínez-Leal JF, Fernández R, Martínez V, Valenzuela C, Lillo MP, Galmarini CM.

PLoS One. 2015 Oct 16;10(10):e0140782. doi: 10.1371/journal.pone.0140782. eCollection 2015.

4.

Levels of SCS7/FA2H-mediated fatty acid 2-hydroxylation determine the sensitivity of cells to antitumor PM02734.

Herrero AB, Astudillo AM, Balboa MA, Cuevas C, Balsinde J, Moreno S.

Cancer Res. 2008 Dec 1;68(23):9779-87. doi: 10.1158/0008-5472.CAN-08-1981.

5.

ErbB3 expression predicts sensitivity to elisidepsin treatment: in vitro synergism with cisplatin, paclitaxel and gemcitabine in lung, breast and colon cancer cell lines.

Teixidó C, Arguelaguet E, Pons B, Aracil M, Jimeno J, Somoza R, Marés R, Ramón Y Cajal S, Hernández-Losa J.

Int J Oncol. 2012 Jul;41(1):317-24. doi: 10.3892/ijo.2012.1425. Epub 2012 Apr 3.

PMID:
22485250
6.

Epithelial-mesenchymal transition markers and HER3 expression are predictors of elisidepsin treatment response in breast and pancreatic cancer cell lines.

Teixidó C, Marés R, Aracil M, Ramón y Cajal S, Hernández-Losa J.

PLoS One. 2013;8(1):e53645. doi: 10.1371/journal.pone.0053645. Epub 2013 Jan 8.

7.

Predictive factors of sensitivity to elisidepsin, a novel Kahalalide F-derived marine compound.

Serova M, de Gramont A, Bieche I, Riveiro ME, Galmarini CM, Aracil M, Jimeno J, Faivre S, Raymond E.

Mar Drugs. 2013 Mar 20;11(3):944-59. doi: 10.3390/md11030944.

8.

HIF-1 is induced via EGFR activation and mediates resistance to anoikis-like cell death under lipid rafts/caveolae-disrupting stress.

Lee SH, Koo KH, Park JW, Kim HJ, Ye SK, Park JB, Park BK, Kim YN.

Carcinogenesis. 2009 Dec;30(12):1997-2004. doi: 10.1093/carcin/bgp233.

PMID:
19789263
9.
10.

Lipid rafts: cell surface platforms for T cell signaling.

Magee T, Pirinen N, Adler J, Pagakis SN, Parmryd I.

Biol Res. 2002;35(2):127-31. Review.

PMID:
12415729
11.

Partitioning of liquid-ordered/liquid-disordered membrane microdomains induced by the fluidifying effect of 2-hydroxylated fatty acid derivatives.

Ibarguren M, López DJ, Encinar JA, González-Ros JM, Busquets X, Escribá PV.

Biochim Biophys Acta. 2013 Nov;1828(11):2553-63. doi: 10.1016/j.bbamem.2013.06.014. Epub 2013 Jun 18.

12.

The insecticide 1,1,1-trichloro-2,2-bis(p-chlorophenyl) ethane (DDT) alters the membrane raft location of the TSH receptor stably expressed in Chinese hamster ovary cells.

De Gregorio F, Pellegrino M, Picchietti S, Belardinelli MC, Taddei AR, Fausto AM, Rossi M, Maggio R, Giorgi F.

Toxicol Appl Pharmacol. 2011 Jun 1;253(2):121-9. doi: 10.1016/j.taap.2011.03.018. Epub 2011 Apr 3.

PMID:
21466821
13.

Chemical-physical changes in cell membrane microdomains of breast cancer cells after omega-3 PUFA incorporation.

Corsetto PA, Cremona A, Montorfano G, Jovenitti IE, Orsini F, Arosio P, Rizzo AM.

Cell Biochem Biophys. 2012 Sep;64(1):45-59. doi: 10.1007/s12013-012-9365-y.

14.

A protective role for lipid raft cholesterol against amyloid-induced membrane damage in human neuroblastoma cells.

Cecchi C, Nichino D, Zampagni M, Bernacchioni C, Evangelisti E, Pensalfini A, Liguri G, Gliozzi A, Stefani M, Relini A.

Biochim Biophys Acta. 2009 Oct;1788(10):2204-16. doi: 10.1016/j.bbamem.2009.07.019. Epub 2009 Aug 6.

15.

Docosahexaenoic acid modifies the clustering and size of lipid rafts and the lateral organization and surface expression of MHC class I of EL4 cells.

Shaikh SR, Rockett BD, Salameh M, Carraway K.

J Nutr. 2009 Sep;139(9):1632-9. doi: 10.3945/jn.109.108720. Epub 2009 Jul 29.

16.

Glucocorticoids alter the lipid and protein composition of membrane rafts of a murine T cell hybridoma.

Van Laethem F, Liang X, Andris F, Urbain J, Vandenbranden M, Ruysschaert JM, Resh MD, Stulnig TM, Leo O.

J Immunol. 2003 Mar 15;170(6):2932-9.

17.
18.

Some new faces of membrane microdomains: a complex confocal fluorescence, differential polarization, and FCS imaging study on live immune cells.

Gombos I, Steinbach G, Pomozi I, Balogh A, Vámosi G, Gansen A, László G, Garab G, Matkó J.

Cytometry A. 2008 Mar;73(3):220-9. doi: 10.1002/cyto.a.20516.

19.

Lipid Rafts Are Physiologic Membrane Microdomains Necessary for the Morphogenic and Developmental Functions of Glial Cell Line-Derived Neurotrophic Factor In Vivo.

Tsui CC, Gabreski NA, Hein SJ, Pierchala BA.

J Neurosci. 2015 Sep 23;35(38):13233-43. doi: 10.1523/JNEUROSCI.2935-14.2015.

20.

Molecular pharmacodynamics of PM02734 (elisidepsin) as single agent and in combination with erlotinib; synergistic activity in human non-small cell lung cancer cell lines and xenograft models.

Ling YH, Aracil M, Jimeno J, Perez-Soler R, Zou Y.

Eur J Cancer. 2009 Jul;45(10):1855-64. doi: 10.1016/j.ejca.2009.03.003. Epub 2009 Apr 5.

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