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Items: 1 to 20 of 97

1.

Cerebrolysin reduces amyloid-β deposits, apoptosis and autophagy in the thalamus and improves functional recovery after cortical infarction.

Xing S, Zhang J, Dang C, Liu G, Zhang Y, Li J, Fan Y, Pei Z, Zeng J.

J Neurol Sci. 2014 Feb 15;337(1-2):104-11. doi: 10.1016/j.jns.2013.11.028. Epub 2013 Nov 26.

PMID:
24315581
2.

Beclin 1 knockdown inhibits autophagic activation and prevents the secondary neurodegenerative damage in the ipsilateral thalamus following focal cerebral infarction.

Xing S, Zhang Y, Li J, Zhang J, Li Y, Dang C, Li C, Fan Y, Yu J, Pei Z, Zeng J.

Autophagy. 2012 Jan;8(1):63-76. doi: 10.4161/auto.8.1.18217. Epub 2012 Jan 1.

PMID:
22108007
3.
4.

Autophagosomes accumulation is associated with β-amyloid deposits and secondary damage in the thalamus after focal cortical infarction in hypertensive rats.

Zhang J, Zhang Y, Li J, Xing S, Li C, Li Y, Dang C, Fan Y, Yu J, Pei Z, Zeng J.

J Neurochem. 2012 Feb;120(4):564-73. doi: 10.1111/j.1471-4159.2011.07496.x. Epub 2011 Oct 20.

5.

Bepridil decreases Aβ and calcium levels in the thalamus after middle cerebral artery occlusion in rats.

Sarajärvi T, Lipsanen A, Mäkinen P, Peräniemi S, Soininen H, Haapasalo A, Jolkkonen J, Hiltunen M.

J Cell Mol Med. 2012 Nov;16(11):2754-67. doi: 10.1111/j.1582-4934.2012.01599.x.

6.

Tongxinluo attenuates neuronal loss and enhances neurogenesis and angiogenesis in the ipsilateral thalamus and improves neurological outcome after focal cortical infarction in hypertensive rats.

Chen L, Wang X, Chen X, Xing S, Zhang J, Li J, Dang C, Liu G, Dang G, Zeng J.

Restor Neurol Neurosci. 2014;32(4):533-46. doi: 10.3233/RNN-140403.

PMID:
24927788
7.

Focal cerebral ischemia in rats alters APP processing and expression of Abeta peptide degrading enzymes in the thalamus.

Hiltunen M, Mäkinen P, Peräniemi S, Sivenius J, van Groen T, Soininen H, Jolkkonen J.

Neurobiol Dis. 2009 Jul;35(1):103-13. doi: 10.1016/j.nbd.2009.04.009. Epub 2009 May 5.

PMID:
19426802
8.

Ebselen reduces autophagic activation and cell death in the ipsilateral thalamus following focal cerebral infarction.

Li Y, Zhang J, Chen L, Xing S, Li J, Zhang Y, Li C, Pei Z, Zeng J.

Neurosci Lett. 2015 Jul 23;600:206-12. doi: 10.1016/j.neulet.2015.06.024. Epub 2015 Jun 16.

PMID:
26091880
9.

Improvement in functional recovery with administration of Cerebrolysin after experimental closed head injury.

Zhang Y, Chopp M, Meng Y, Zhang ZG, Doppler E, Mahmood A, Xiong Y.

J Neurosurg. 2013 Jun;118(6):1343-55. doi: 10.3171/2013.3.JNS122061. Epub 2013 Apr 12.

PMID:
23581594
10.
11.

Hyperphosphorylation of tau protein in the ipsilateral thalamus after focal cortical infarction in rats.

Dong DW, Zhang YS, Yang WY, Wang-Qin RQ, Xu AD, Ruan YW.

Brain Res. 2014 Jan 16;1543:280-9. doi: 10.1016/j.brainres.2013.11.004. Epub 2013 Nov 8.

PMID:
24216136
12.

Cerebrolysin enhances functional recovery following focal cerebral infarction in rats.

Ren J, Sietsma D, Qiu S, Moessler H, Finklestein SP.

Restor Neurol Neurosci. 2007;25(1):25-31.

PMID:
17473393
13.

Caspase inhibition attenuates accumulation of beta-amyloid by reducing beta-secretase production and activity in rat brains after stroke.

Xiong M, Zhang T, Zhang LM, Lu SD, Huang YL, Sun FY.

Neurobiol Dis. 2008 Dec;32(3):433-41. doi: 10.1016/j.nbd.2008.08.007. Epub 2008 Sep 4.

PMID:
18805488
14.

Necrosis, apoptosis and hybrid death in the cortex and thalamus after barrel cortex ischemia in rats.

Wei L, Ying DJ, Cui L, Langsdorf J, Yu SP.

Brain Res. 2004 Oct 1;1022(1-2):54-61.

PMID:
15353213
15.

Lamotrigine Reduces β-Site AβPP-Cleaving Enzyme 1 Protein Levels Through Induction of Autophagy.

Wu H, Lu MH, Wang W, Zhang MY, Zhu QQ, Xia YY, Xu RX, Yang Y, Chen LH, Ma QH.

J Alzheimers Dis. 2015;46(4):863-76. doi: 10.3233/JAD-143162.

PMID:
25854934
16.

Cerebrolysin dose-dependently improves neurological outcome in rats after acute stroke: A prospective, randomized, blinded, and placebo-controlled study.

Zhang L, Chopp M, Lu M, Zhang T, Winter S, Doppler E, Meier D, Chao L, Eapen A, Pabla P, Gang Zhang Z.

Int J Stroke. 2016 Apr;11(3):347-55. doi: 10.1177/1747493015625645. Epub 2016 Jan 12.

PMID:
26763925
17.

Lack of secondary pathology in the thalamus after focal cerebral ischemia in nonhuman primates.

Lipsanen A, Kalesnykas G, Pro-Sistiaga P, Hiltunen M, Vanninen R, Bernaudin M, Touzani O, Jolkkonen J.

Exp Neurol. 2013 Oct;248:224-7. doi: 10.1016/j.expneurol.2013.06.016. Epub 2013 Jun 26.

PMID:
23810737
18.

Aβ1-42 monomers or oligomers have different effects on autophagy and apoptosis.

Guglielmotto M, Monteleone D, Piras A, Valsecchi V, Tropiano M, Ariano S, Fornaro M, Vercelli A, Puyal J, Arancio O, Tabaton M, Tamagno E.

Autophagy. 2014 Oct 1;10(10):1827-43. doi: 10.4161/auto.30001. Epub 2014 Aug 12.

19.

Mutant ubiquitin-mediated beta-secretase stability via activation of caspase-3 is related to beta-amyloid accumulation in ischemic striatum in rats.

Zhang Y, Xiong M, Yan RQ, Sun FY.

J Cereb Blood Flow Metab. 2010 Mar;30(3):566-75. doi: 10.1038/jcbfm.2009.228. Epub 2009 Oct 21.

20.

Mitochondria-targeted catalase reduces abnormal APP processing, amyloid β production and BACE1 in a mouse model of Alzheimer's disease: implications for neuroprotection and lifespan extension.

Mao P, Manczak M, Calkins MJ, Truong Q, Reddy TP, Reddy AP, Shirendeb U, Lo HH, Rabinovitch PS, Reddy PH.

Hum Mol Genet. 2012 Jul 1;21(13):2973-90. doi: 10.1093/hmg/dds128. Epub 2012 Apr 5.

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