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Items: 1 to 20 of 111

1.

Crystal structure of TET2-DNA complex: insight into TET-mediated 5mC oxidation.

Hu L, Li Z, Cheng J, Rao Q, Gong W, Liu M, Shi YG, Zhu J, Wang P, Xu Y.

Cell. 2013 Dec 19;155(7):1545-55. doi: 10.1016/j.cell.2013.11.020. Epub 2013 Dec 5.

2.

Structural insight into substrate preference for TET-mediated oxidation.

Hu L, Lu J, Cheng J, Rao Q, Li Z, Hou H, Lou Z, Zhang L, Li W, Gong W, Liu M, Sun C, Yin X, Li J, Tan X, Wang P, Wang Y, Fang D, Cui Q, Yang P, He C, Jiang H, Luo C, Xu Y.

Nature. 2015 Nov 5;527(7576):118-22. doi: 10.1038/nature15713. Epub 2015 Oct 28.

PMID:
26524525
3.

Probing DNA by 2-OG-dependent dioxygenase.

Tsai CL, Tainer JA.

Cell. 2013 Dec 19;155(7):1448-50. doi: 10.1016/j.cell.2013.12.002.

4.

Ascorbic acid enhances Tet-mediated 5-methylcytosine oxidation and promotes DNA demethylation in mammals.

Yin R, Mao SQ, Zhao B, Chong Z, Yang Y, Zhao C, Zhang D, Huang H, Gao J, Li Z, Jiao Y, Li C, Liu S, Wu D, Gu W, Yang YG, Xu GL, Wang H.

J Am Chem Soc. 2013 Jul 17;135(28):10396-403. doi: 10.1021/ja4028346. Epub 2013 Jul 1.

PMID:
23768208
5.

Structure of a Naegleria Tet-like dioxygenase in complex with 5-methylcytosine DNA.

Hashimoto H, Pais JE, Zhang X, Saleh L, Fu ZQ, Dai N, Corrêa IR Jr, Zheng Y, Cheng X.

Nature. 2014 Feb 20;506(7488):391-5. doi: 10.1038/nature12905. Epub 2013 Dec 25.

6.

Modulation of TET2 expression and 5-methylcytosine oxidation by the CXXC domain protein IDAX.

Ko M, An J, Bandukwala HS, Chavez L, Aijö T, Pastor WA, Segal MF, Li H, Koh KP, Lähdesmäki H, Hogan PG, Aravind L, Rao A.

Nature. 2013 May 2;497(7447):122-6. doi: 10.1038/nature12052. Epub 2013 Apr 7.

7.

MBD3L2 promotes Tet2 enzymatic activity for mediating 5-methylcytosine oxidation.

Peng L, Li Y, Xi Y, Li W, Li J, Lv R, Zhang L, Zou Q, Dong S, Luo H, Wu F, Yu W.

J Cell Sci. 2016 Mar 1;129(5):1059-71. doi: 10.1242/jcs.179044. Epub 2016 Jan 14.

8.

DNA methylation: TET proteins-guardians of CpG islands?

Williams K, Christensen J, Helin K.

EMBO Rep. 2011 Dec 23;13(1):28-35. doi: 10.1038/embor.2011.233. Review.

9.

TET proteins and 5-methylcytosine oxidation in hematological cancers.

Ko M, An J, Pastor WA, Koralov SB, Rajewsky K, Rao A.

Immunol Rev. 2015 Jan;263(1):6-21. doi: 10.1111/imr.12239. Review.

10.

Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1.

Tahiliani M, Koh KP, Shen Y, Pastor WA, Bandukwala H, Brudno Y, Agarwal S, Iyer LM, Liu DR, Aravind L, Rao A.

Science. 2009 May 15;324(5929):930-5. doi: 10.1126/science.1170116. Epub 2009 Apr 16.

11.

Structure and Function of TET Enzymes.

Yin X, Xu Y.

Adv Exp Med Biol. 2016;945:275-302. Review.

PMID:
27826843
12.

Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2.

Ko M, Huang Y, Jankowska AM, Pape UJ, Tahiliani M, Bandukwala HS, An J, Lamperti ED, Koh KP, Ganetzky R, Liu XS, Aravind L, Agarwal S, Maciejewski JP, Rao A.

Nature. 2010 Dec 9;468(7325):839-43. doi: 10.1038/nature09586.

13.

Recognition of hemi-methylated DNA by the SRA protein UHRF1 by a base-flipping mechanism.

Arita K, Ariyoshi M, Tochio H, Nakamura Y, Shirakawa M.

Nature. 2008 Oct 9;455(7214):818-21. doi: 10.1038/nature07249. Epub 2008 Sep 3.

PMID:
18772891
14.

A computational investigation on the substrate preference of ten-eleven-translocation 2 (TET2).

Lu J, Hu L, Cheng J, Fang D, Wang C, Yu K, Jiang H, Cui Q, Xu Y, Luo C.

Phys Chem Chem Phys. 2016 Feb 14;18(6):4728-38. doi: 10.1039/c5cp07266b.

PMID:
26799843
15.

PRDM14 promotes active DNA demethylation through the ten-eleven translocation (TET)-mediated base excision repair pathway in embryonic stem cells.

Okashita N, Kumaki Y, Ebi K, Nishi M, Okamoto Y, Nakayama M, Hashimoto S, Nakamura T, Sugasawa K, Kojima N, Takada T, Okano M, Seki Y.

Development. 2014 Jan;141(2):269-80. doi: 10.1242/dev.099622. Epub 2013 Dec 11.

16.

Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA.

He YF, Li BZ, Li Z, Liu P, Wang Y, Tang Q, Ding J, Jia Y, Chen Z, Li L, Sun Y, Li X, Dai Q, Song CX, Zhang K, He C, Xu GL.

Science. 2011 Sep 2;333(6047):1303-7. doi: 10.1126/science.1210944. Epub 2011 Aug 4.

17.

Acetylation Enhances TET2 Function in Protecting against Abnormal DNA Methylation during Oxidative Stress.

Zhang YW, Wang Z, Xie W, Cai Y, Xia L, Easwaran H, Luo J, Yen RC, Li Y, Baylin SB.

Mol Cell. 2017 Jan 19;65(2):323-335. doi: 10.1016/j.molcel.2016.12.013.

18.

Intrinsic and extrinsic connections of Tet3 dioxygenase with CXXC zinc finger modules.

Liu N, Wang M, Deng W, Schmidt CS, Qin W, Leonhardt H, Spada F.

PLoS One. 2013 May 14;8(5):e62755. doi: 10.1371/journal.pone.0062755. Print 2013.

19.

DNA recognition of 5-carboxylcytosine by a Zfp57 mutant at an atomic resolution of 0.97 Å.

Liu Y, Olanrewaju YO, Zhang X, Cheng X.

Biochemistry. 2013 Dec 23;52(51):9310-7. doi: 10.1021/bi401360n. Epub 2013 Nov 20.

20.

Crystal structure of a ternary SAP-1/SRF/c-fos SRE DNA complex.

Mo Y, Ho W, Johnston K, Marmorstein R.

J Mol Biol. 2001 Nov 30;314(3):495-506.

PMID:
11846562

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