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Items: 1 to 20 of 138

1.

AMD3100 improves ovariectomy-induced osteoporosis in mice by facilitating mobilization of hematopoietic stem/progenitor cells.

Im JY, Min WK, Park MH, Kim N, Lee JK, Jin HK, Choi JY, Kim SY, Bae JS.

BMB Rep. 2014 Aug;47(8):439-44.

2.

Insights into the mechanism of enhanced mobilization of hematopoietic progenitor cells and release of CXCL12 by a combination of AMD3100 and aminoglycoside-polyarginine conjugates.

Berchanski A, Kalinkovich A, Ludin A, Lapidot T, Lapidot A.

FEBS J. 2011 Nov;278(21):4150-65. doi: 10.1111/j.1742-4658.2011.08348.x. Epub 2011 Oct 4.

3.

Effective mobilization of hematopoietic progenitor cells in G-CSF mobilization defective CD26-/- mice through AMD3100-induced disruption of the CXCL12-CXCR4 axis.

Paganessi LA, Walker AL, Tan LL, Holmes I, Rich E, Fung HC, Christopherson KW 2nd.

Exp Hematol. 2011 Mar;39(3):384-90. doi: 10.1016/j.exphem.2010.12.003. Epub 2010 Dec 17.

5.

Rapid mobilization of hematopoietic progenitors by AMD3100 and catecholamines is mediated by CXCR4-dependent SDF-1 release from bone marrow stromal cells.

Dar A, Schajnovitz A, Lapid K, Kalinkovich A, Itkin T, Ludin A, Kao WM, Battista M, Tesio M, Kollet O, Cohen NN, Margalit R, Buss EC, Baleux F, Oishi S, Fujii N, Larochelle A, Dunbar CE, Broxmeyer HE, Frenette PS, Lapidot T.

Leukemia. 2011 Aug;25(8):1286-1296. doi: 10.1038/leu.2011.62. Epub 2011 Apr 15. Erratum in: Leukemia. 2011 Aug;25(8):1378.

6.

Inhibitory effect of CXC chemokine receptor 4 antagonist AMD3100 on bleomycin induced murine pulmonary fibrosis.

Song JS, Kang CM, Kang HH, Yoon HK, Kim YK, Kim KH, Moon HS, Park SH.

Exp Mol Med. 2010 Jun 30;42(6):465-72.

7.

Evidence for the involvement of sphingosine-1-phosphate in the homing and engraftment of hematopoietic stem cells to bone marrow.

Adamiak M, Borkowska S, Wysoczynski M, Suszynska M, Kucia M, Rokosh G, Abdel-Latif A, Ratajczak J, Ratajczak MZ.

Oncotarget. 2015 Aug 7;6(22):18819-28.

8.

CXC-chemokine receptor 4 antagonist AMD3100 promotes cardiac functional recovery after ischemia/reperfusion injury via endothelial nitric oxide synthase-dependent mechanism.

Jujo K, Ii M, Sekiguchi H, Klyachko E, Misener S, Tanaka T, Tongers J, Roncalli J, Renault MA, Thorne T, Ito A, Clarke T, Kamide C, Tsurumi Y, Hagiwara N, Qin G, Asahi M, Losordo DW.

Circulation. 2013 Jan 1;127(1):63-73. doi: 10.1161/CIRCULATIONAHA.112.099242. Epub 2012 Nov 30.

9.

Update on clinical experience with AMD3100, an SDF-1/CXCL12-CXCR4 inhibitor, in mobilization of hematopoietic stem and progenitor cells.

Pusic I, DiPersio JF.

Curr Opin Hematol. 2010 Jul;17(4):319-26. doi: 10.1097/MOH.0b013e328338b7d5. Review.

PMID:
20473162
10.

CXCR4 and mobilization of hematopoietic precursors.

Rettig MP, Ramirez P, Nervi B, DiPersio JF.

Methods Enzymol. 2009;460:57-90. doi: 10.1016/S0076-6879(09)05203-3.

PMID:
19446720
11.

Sphingosine-1-phosphate facilitates trafficking of hematopoietic stem cells and their mobilization by CXCR4 antagonists in mice.

Juarez JG, Harun N, Thien M, Welschinger R, Baraz R, Pena AD, Pitson SM, Rettig M, DiPersio JF, Bradstock KF, Bendall LJ.

Blood. 2012 Jan 19;119(3):707-16. doi: 10.1182/blood-2011-04-348904. Epub 2011 Nov 2.

12.

AMD3100 and CD26 modulate mobilization, engraftment, and survival of hematopoietic stem and progenitor cells mediated by the SDF-1/CXCL12-CXCR4 axis.

Broxmeyer HE, Hangoc G, Cooper S, Campbell T, Ito S, Mantel C.

Ann N Y Acad Sci. 2007 Jun;1106:1-19. Epub 2007 Mar 14.

PMID:
17360804
13.

Small molecule Me6TREN mobilizes hematopoietic stem/progenitor cells by activating MMP-9 expression and disrupting SDF-1/CXCR4 axis.

Zhang J, Ren X, Shi W, Wang S, Chen H, Zhang B, Wang Z, Zhou Y, Chen L, Zhang R, Lv Y, Zhou J, Nan X, He L, Yue W, Li Y, Pei X.

Blood. 2014 Jan 16;123(3):428-41. doi: 10.1182/blood-2013-04-498535. Epub 2013 Nov 6.

15.

Sphingosine-1-phosphate-mediated mobilization of hematopoietic stem/progenitor cells during intravascular hemolysis requires attenuation of SDF-1-CXCR4 retention signaling in bone marrow.

Mierzejewska K, Klyachkin YM, Ratajczak J, Abdel-Latif A, Kucia M, Ratajczak MZ.

Biomed Res Int. 2013;2013:814549. doi: 10.1155/2013/814549. Epub 2013 Dec 29.

17.
18.

CXCR4-mediated bone marrow progenitor cell maintenance and mobilization are modulated by c-kit activity.

Cheng M, Zhou J, Wu M, Boriboun C, Thorne T, Liu T, Xiang Z, Zeng Q, Tanaka T, Tang YL, Kishore R, Tomasson MH, Miller RJ, Losordo DW, Qin G.

Circ Res. 2010 Oct 29;107(9):1083-93. doi: 10.1161/CIRCRESAHA.110.220970. Epub 2010 Sep 16.

19.

Plerixafor (AMD3100) induces prolonged mobilization of acute lymphoblastic leukemia cells and increases the proportion of cycling cells in the blood in mice.

Welschinger R, Liedtke F, Basnett J, Dela Pena A, Juarez JG, Bradstock KF, Bendall LJ.

Exp Hematol. 2013 Mar;41(3):293-302.e1. doi: 10.1016/j.exphem.2012.11.004. Epub 2012 Nov 23.

PMID:
23178377
20.

Rapid mobilization of murine and human hematopoietic stem and progenitor cells with AMD3100, a CXCR4 antagonist.

Broxmeyer HE, Orschell CM, Clapp DW, Hangoc G, Cooper S, Plett PA, Liles WC, Li X, Graham-Evans B, Campbell TB, Calandra G, Bridger G, Dale DC, Srour EF.

J Exp Med. 2005 Apr 18;201(8):1307-18.

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