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Items: 1 to 20 of 74

1.

Multiplex cytological profiling assay to measure diverse cellular states.

Gustafsdottir SM, Ljosa V, Sokolnicki KL, Anthony Wilson J, Walpita D, Kemp MM, Petri Seiler K, Carrel HA, Golub TR, Schreiber SL, Clemons PA, Carpenter AE, Shamji AF.

PLoS One. 2013 Dec 2;8(12):e80999. doi: 10.1371/journal.pone.0080999. eCollection 2013.

2.

Cell Painting, a high-content image-based assay for morphological profiling using multiplexed fluorescent dyes.

Bray MA, Singh S, Han H, Davis CT, Borgeson B, Hartland C, Kost-Alimova M, Gustafsdottir SM, Gibson CC, Carpenter AE.

Nat Protoc. 2016 Sep;11(9):1757-74. doi: 10.1038/nprot.2016.105. Epub 2016 Aug 25.

3.

Compound classification using image-based cellular phenotypes.

Adams CL, Kutsyy V, Coleman DA, Cong G, Crompton AM, Elias KA, Oestreicher DR, Trautman JK, Vaisberg E.

Methods Enzymol. 2006;414:440-68.

PMID:
17110206
4.

Phenotype-Guided Natural Products Discovery Using Cytological Profiling.

Ochoa JL, Bray WM, Lokey RS, Linington RG.

J Nat Prod. 2015 Sep 25;78(9):2242-8. doi: 10.1021/acs.jnatprod.5b00455. Epub 2015 Aug 21.

PMID:
26292657
5.

Bridging Functional and Structural Cardiotoxicity Assays Using Human Embryonic Stem Cell-Derived Cardiomyocytes for a More Comprehensive Risk Assessment.

Clements M, Millar V, Williams AS, Kalinka S.

Toxicol Sci. 2015 Nov;148(1):241-60. doi: 10.1093/toxsci/kfv180. Epub 2015 Aug 10.

PMID:
26259608
6.

Large-scale cytological profiling for functional analysis of bioactive compounds.

Woehrmann MH, Bray WM, Durbin JK, Nisam SC, Michael AK, Glassey E, Stuart JM, Lokey RS.

Mol Biosyst. 2013 Nov;9(11):2604-17. doi: 10.1039/c3mb70245f.

PMID:
24056581
7.

High-content assay to study protein prenylation.

Simonen M, Ibig-Rehm Y, Hofmann G, Zimmermann J, Albrecht G, Magnier M, Heidinger V, Gabriel D.

J Biomol Screen. 2008 Jul;13(6):456-67. doi: 10.1177/1087057108318757. Epub 2008 May 28.

PMID:
18509097
8.

A rapid and high content assay that measures cyto-ID-stained autophagic compartments and estimates autophagy flux with potential clinical applications.

Guo S, Liang Y, Murphy SF, Huang A, Shen H, Kelly DF, Sobrado P, Sheng Z.

Autophagy. 2015;11(3):560-72. doi: 10.1080/15548627.2015.1017181.

9.

Multi-pathway cellular analysis of compound selectivity.

Hancock MK, Lebakken CS, Wang J, Bi K.

Mol Biosyst. 2010 Oct;6(10):1834-43. doi: 10.1039/c003669b. Epub 2010 Jun 30.

PMID:
20593073
10.
11.

Interactive fluorophore and quencher pairs for labeling fluorescent nucleic acid hybridization probes.

Marras SA.

Mol Biotechnol. 2008 Mar;38(3):247-55. Epub 2007 Nov 6.

PMID:
17985254
12.

Protein translocation assays: key tools for accessing new biological information with high-throughput microscopy.

Heydorn A, Lundholt BK, Praestegaard M, Pagliaro L.

Methods Enzymol. 2006;414:513-30.

PMID:
17110209
13.

Multidimensional drug profiling by automated microscopy.

Perlman ZE, Slack MD, Feng Y, Mitchison TJ, Wu LF, Altschuler SJ.

Science. 2004 Nov 12;306(5699):1194-8.

14.

Development of a high throughput cell-based assay for soluble epoxide hydrolase using BacMam technology.

Xie W, Tang X, Lu Q, Ames RS, Ratcliffe SJ, Li H.

Mol Biotechnol. 2010 Jul;45(3):207-17. doi: 10.1007/s12033-010-9271-8.

PMID:
20339956
15.

Bioactive Potential of Marine Macroalgae from the Central Red Sea (Saudi Arabia) Assessed by High-Throughput Imaging-Based Phenotypic Profiling.

Kremb S, Müller C, Schmitt-Kopplin P, Voolstra CR.

Mar Drugs. 2017 Mar 20;15(3). pii: E80. doi: 10.3390/md15030080.

16.

FRET-based calcium imaging: a tool for high-throughput/content phenotypic drug screening in Alzheimer disease.

Honarnejad K, Kirsch AK, Daschner A, Szybinska A, Kuznicki J, Herms J.

J Biomol Screen. 2013 Dec;18(10):1309-20. doi: 10.1177/1087057113502672.

PMID:
24221842
17.

Development and implementation of multiplexed cell-based imaging assays.

Howell BJ, Lee S, Sepp-Lorenzino L.

Methods Enzymol. 2006;414:284-300.

PMID:
17110198
18.

Morphobase, an encyclopedic cell morphology database, and its use for drug target identification.

Futamura Y, Kawatani M, Kazami S, Tanaka K, Muroi M, Shimizu T, Tomita K, Watanabe N, Osada H.

Chem Biol. 2012 Dec 21;19(12):1620-30. doi: 10.1016/j.chembiol.2012.10.014.

19.

Biomolecular detection employing the Interferometric Reflectance Imaging Sensor (IRIS).

Lopez CA, Daaboul GG, Ahn S, Reddington AP, Monroe MR, Zhang X, Irani RJ, Yu C, Genco CA, Cretich M, Chiari M, Goldberg BB, Connor JH, Ünlü MS.

J Vis Exp. 2011 May 3;(51). pii: 2694. doi: 10.3791/2694.

20.

Comparison of 3 assay systems using a common probe substrate, calcein AM, for studying P-gp using a selected set of compounds.

Szerémy P, Pál A, Méhn D, Tóth B, Fülöp F, Krajcsi P, Herédi-Szabó K.

J Biomol Screen. 2011 Jan;16(1):112-9. doi: 10.1177/1087057110385230. Epub 2010 Nov 5.

PMID:
21057029

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