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Items: 1 to 20 of 150

1.

Genetic reduction of vascular endothelial growth factor receptor 2 rescues aberrant angiogenesis caused by epsin deficiency.

Tessneer KL, Pasula S, Cai X, Dong Y, McManus J, Liu X, Yu L, Hahn S, Chang B, Chen Y, Griffin C, Xia L, Adams RH, Chen H.

Arterioscler Thromb Vasc Biol. 2014 Feb;34(2):331-7. doi: 10.1161/ATVBAHA.113.302586. Erratum in: Arterioscler Thromb Vasc Biol. 2014 Apr;34(4):e7.

2.

Endothelial epsin deficiency decreases tumor growth by enhancing VEGF signaling.

Pasula S, Cai X, Dong Y, Messa M, McManus J, Chang B, Liu X, Zhu H, Mansat RS, Yoon SJ, Hahn S, Keeling J, Saunders D, Ko G, Knight J, Newton G, Luscinskas F, Sun X, Towner R, Lupu F, Xia L, Cremona O, De Camilli P, Min W, Chen H.

J Clin Invest. 2012 Dec;122(12):4424-38. doi: 10.1172/JCI64537.

3.

Selective Targeting of a Novel Epsin-VEGFR2 Interaction Promotes VEGF-Mediated Angiogenesis.

Rahman HN, Wu H, Dong Y, Pasula S, Wen A, Sun Y, Brophy ML, Tessneer KL, Cai X, McManus J, Chang B, Kwak S, Rahman NS, Xu W, Fernandes C, Mcdaniel JM, Xia L, Smith L, Srinivasan RS, Chen H.

Circ Res. 2016 Mar 18;118(6):957-69. doi: 10.1161/CIRCRESAHA.115.307679.

PMID:
26879230
4.

Downregulation of endothelial microRNA-200b supports cutaneous wound angiogenesis by desilencing GATA binding protein 2 and vascular endothelial growth factor receptor 2.

Chan YC, Roy S, Khanna S, Sen CK.

Arterioscler Thromb Vasc Biol. 2012 Jun;32(6):1372-82. doi: 10.1161/ATVBAHA.112.248583.

5.

Liver X receptor activation reduces angiogenesis by impairing lipid raft localization and signaling of vascular endothelial growth factor receptor-2.

Noghero A, Perino A, Seano G, Saglio E, Lo Sasso G, Veglio F, Primo L, Hirsch E, Bussolino F, Morello F.

Arterioscler Thromb Vasc Biol. 2012 Sep;32(9):2280-8. doi: 10.1161/ATVBAHA.112.250621.

6.

Endothelial deletion of phospholipase D2 reduces hypoxic response and pathological angiogenesis.

Ghim J, Moon JS, Lee CS, Lee J, Song P, Lee A, Jang JH, Kim D, Yoon JH, Koh YJ, Chelakkot C, Kang BJ, Kim JM, Kim KL, Yang YR, Kim Y, Kim SH, Hwang D, Suh PG, Koh GY, Kong YY, Ryu SH.

Arterioscler Thromb Vasc Biol. 2014 Aug;34(8):1697-703. doi: 10.1161/ATVBAHA.114.303416.

7.

AIP1 functions as an endogenous inhibitor of VEGFR2-mediated signaling and inflammatory angiogenesis in mice.

Zhang H, He Y, Dai S, Xu Z, Luo Y, Wan T, Luo D, Jones D, Tang S, Chen H, Sessa WC, Min W.

J Clin Invest. 2008 Dec;118(12):3904-16. doi: 10.1172/JCI36168.

8.

MULTIMERIN2 impairs tumor angiogenesis and growth by interfering with VEGF-A/VEGFR2 pathway.

Lorenzon E, Colladel R, Andreuzzi E, Marastoni S, Todaro F, Schiappacassi M, Ligresti G, Colombatti A, Mongiat M.

Oncogene. 2012 Jun 28;31(26):3136-47. doi: 10.1038/onc.2011.487.

PMID:
22020326
9.
10.

Endothelial monocyte activating polypeptide II interferes with VEGF-induced proangiogenic signaling.

Awasthi N, Schwarz MA, Verma V, Cappiello C, Schwarz RE.

Lab Invest. 2009 Jan;89(1):38-46. doi: 10.1038/labinvest.2008.106.

11.

Injury-Mediated Vascular Regeneration Requires Endothelial ER71/ETV2.

Park C, Lee TJ, Bhang SH, Liu F, Nakamura R, Oladipupo SS, Pitha-Rowe I, Capoccia B, Choi HS, Kim TM, Urao N, Ushio-Fukai M, Lee D, Miyoshi H, Kim BS, Lim DS, Apte RS, Ornitz DM, Choi K.

Arterioscler Thromb Vasc Biol. 2016 Jan;36(1):86-96. doi: 10.1161/ATVBAHA.115.306430.

12.

Necl-5/poliovirus receptor interacts with VEGFR2 and regulates VEGF-induced angiogenesis.

Kinugasa M, Amano H, Satomi-Kobayashi S, Nakayama K, Miyata M, Kubo Y, Nagamatsu Y, Kurogane Y, Kureha F, Yamana S, Hirata K, Miyoshi J, Takai Y, Rikitake Y.

Circ Res. 2012 Mar 2;110(5):716-26. doi: 10.1161/CIRCRESAHA.111.256834.

13.

Rap1 promotes VEGFR2 activation and angiogenesis by a mechanism involving integrin αvβ₃.

Lakshmikanthan S, Sobczak M, Chun C, Henschel A, Dargatz J, Ramchandran R, Chrzanowska-Wodnicka M.

Blood. 2011 Aug 18;118(7):2015-26. doi: 10.1182/blood-2011-04-349282.

14.

S100A1 deficiency impairs postischemic angiogenesis via compromised proangiogenic endothelial cell function and nitric oxide synthase regulation.

Most P, Lerchenmüller C, Rengo G, Mahlmann A, Ritterhoff J, Rohde D, Goodman C, Busch CJ, Laube F, Heissenberg J, Pleger ST, Weiss N, Katus HA, Koch WJ, Peppel K.

Circ Res. 2013 Jan 4;112(1):66-78. doi: 10.1161/CIRCRESAHA.112.275156.

15.

Endothelial cell FGF signaling is required for injury response but not for vascular homeostasis.

Oladipupo SS, Smith C, Santeford A, Park C, Sene A, Wiley LA, Osei-Owusu P, Hsu J, Zapata N, Liu F, Nakamura R, Lavine KJ, Blumer KJ, Choi K, Apte RS, Ornitz DM.

Proc Natl Acad Sci U S A. 2014 Sep 16;111(37):13379-84. doi: 10.1073/pnas.1324235111.

16.

Motif mimetic of epsin perturbs tumor growth and metastasis.

Dong Y, Wu H, Rahman HN, Liu Y, Pasula S, Tessneer KL, Cai X, Liu X, Chang B, McManus J, Hahn S, Dong J, Brophy ML, Yu L, Song K, Silasi-Mansat R, Saunders D, Njoku C, Song H, Mehta-D'Souza P, Towner R, Lupu F, McEver RP, Xia L, Boerboom D, Srinivasan RS, Chen H.

J Clin Invest. 2015 Dec;125(12):4349-64. doi: 10.1172/JCI80349. Erratum in: J Clin Invest. 2016 Apr 1;126(4):1607.

17.

Protein tyrosine phosphatase 1B impairs diabetic wound healing through vascular endothelial growth factor receptor 2 dephosphorylation.

Zhang J, Li L, Li J, Liu Y, Zhang CY, Zhang Y, Zen K.

Arterioscler Thromb Vasc Biol. 2015 Jan;35(1):163-74. doi: 10.1161/ATVBAHA.114.304705.

18.

Antiangiogenic mechanisms of PJ-8, a novel inhibitor of vascular endothelial growth factor receptor signaling.

Huang SW, Lien JC, Kuo SC, Huang TF.

Carcinogenesis. 2012 May;33(5):1022-30. doi: 10.1093/carcin/bgs127.

PMID:
22436611
19.

Pathological neovascularization is reduced by inactivation of ADAM17 in endothelial cells but not in pericytes.

Weskamp G, Mendelson K, Swendeman S, Le Gall S, Ma Y, Lyman S, Hinoki A, Eguchi S, Guaiquil V, Horiuchi K, Blobel CP.

Circ Res. 2010 Mar 19;106(5):932-40. doi: 10.1161/CIRCRESAHA.109.207415.

20.

PTP1b is a physiologic regulator of vascular endothelial growth factor signaling in endothelial cells.

Lanahan AA, Lech D, Dubrac A, Zhang J, Zhuang ZW, Eichmann A, Simons M.

Circulation. 2014 Sep 9;130(11):902-9. doi: 10.1161/CIRCULATIONAHA.114.009683.

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