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Items: 1 to 20 of 118

1.
2.

Triptolide cooperates with chemotherapy to induce apoptosis in acute myeloid leukemia cells.

Pigneux A, Mahon FX, Uhalde M, Jeanneteau M, Lacombe F, Milpied N, Reiffers J, Belloc F.

Exp Hematol. 2008 Dec;36(12):1648-59. doi: 10.1016/j.exphem.2008.08.002. Epub 2008 Oct 14.

PMID:
18922616
3.

Triptolide, a Chinese herbal extract, enhances drug sensitivity of resistant myeloid leukemia cell lines through downregulation of HIF-1α and Nrf2.

Chen F, Liu Y, Wang S, Guo X, Shi P, Wang W, Xu B.

Pharmacogenomics. 2013 Aug;14(11):1305-17. doi: 10.2217/pgs.13.122.

PMID:
23930677
4.

Triptolide Induces Apoptosis and Synergizes with Cisplatin in Cisplatin-Resistant HNE1/DDP Nasopharyngeal Cancer Cells.

Wang X, Zhang JJ, Sun YM, Zhang J, Wang LR, Li JC, Liu H.

Folia Biol (Praha). 2015;61(5):195-202.

5.

Triptolide induces S phase arrest via the inhibition of cyclin E and CDC25A and triggers apoptosis via caspase- and mitochondrial-dependent signaling pathways in A375.S2 human melanoma cells.

Hung FM, Chen YL, Huang AC, Hsiao YP, Yang JS, Chung MT, Chueh FS, Lu HF, Chung JG.

Oncol Rep. 2013 Mar;29(3):1053-60. doi: 10.3892/or.2013.2230. Epub 2013 Jan 8.

PMID:
23314229
6.

Increased accumulation of hypoxia-inducible factor-1α with reduced transcriptional activity mediates the antitumor effect of triptolide.

Zhou ZL, Luo ZG, Yu B, Jiang Y, Chen Y, Feng JM, Dai M, Tong LJ, Li Z, Li YC, Ding J, Miao ZH.

Mol Cancer. 2010 Oct 11;9:268. doi: 10.1186/1476-4598-9-268.

7.

Triptolide inhibits the proliferation of cells from lymphocytic leukemic cell lines in association with downregulation of NF-κB activity and miR-16-1*.

Meng HT, Zhu L, Ni WM, You LS, Jin J, Qian WB.

Acta Pharmacol Sin. 2011 Apr;32(4):503-11. doi: 10.1038/aps.2010.237. Epub 2011 Mar 28.

8.

Triptolide induces apoptosis in human adrenal cancer NCI-H295 cells through a mitochondrial-dependent pathway.

Wu PP, Liu KC, Huang WW, Ma CY, Lin H, Yang JS, Chung JG.

Oncol Rep. 2011 Feb;25(2):551-7. doi: 10.3892/or.2010.1080. Epub 2010 Dec 8.

PMID:
21152873
9.

Triptolide inhibits the multidrug resistance in prostate cancer cells via the downregulation of MDR1 expression.

Guo Q, Nan XX, Yang JR, Yi L, Liang BL, Wei YB, Zhu N, Hu SB, Zhang H, Luo Y, Xu YF.

Neoplasma. 2013;60(6):598-604. doi: 10.4149/neo_2013_077.

PMID:
23906293
10.

Triptolide modulates the sensitivity of K562/A02 cells to adriamycin by regulating miR-21 expression.

Li H, Hui L, Xu W, Shen H, Chen Q, Long L, Zhu X.

Pharm Biol. 2012 Oct;50(10):1233-40. doi: 10.3109/13880209.2012.665931.

PMID:
22957792
11.

Triptolide synergistically enhances antitumor activity of oxaliplatin in colon carcinoma in vitro and in vivo.

Liu Y, Xiao E, Yuan L, Li G.

DNA Cell Biol. 2014 Jul;33(7):418-25. doi: 10.1089/dna.2014.2356. Epub 2014 Apr 10.

PMID:
24720675
12.

Triptolide enhances the sensitivity of multiple myeloma cells to dexamethasone via microRNAs.

Huang X, Yang M, Jin J.

Leuk Lymphoma. 2012 Jun;53(6):1188-95. doi: 10.3109/10428194.2011.638069. Epub 2012 Feb 13.

PMID:
22260163
13.

[Cordyceps sinensis polysaccharide enhances apoptosis of HL-60 cells induced by triptolide].

Shen YD, Shao XT, Ni YD, Xu H, Tong XM.

Zhejiang Da Xue Xue Bao Yi Xue Ban. 2009 Mar;38(2):158-62. Chinese.

PMID:
19363823
14.

Hsp90 inhibitor BIIB021 enhances triptolide-induced apoptosis of human T-cell acute lymphoblastic leukemia cells in vitro mainly by disrupting p53-MDM2 balance.

Li M, Zhang X, Zhou WJ, Chen YH, Liu H, Liu L, Yang CM, Qan WB.

Acta Pharmacol Sin. 2013 Dec;34(12):1545-53. doi: 10.1038/aps.2013.124. Epub 2013 Nov 18.

15.

Triptolide induces apoptosis and inhibits the growth and angiogenesis of human pancreatic cancer cells by downregulating COX-2 and VEGF.

Ma JX, Sun YL, Wang YQ, Wu HY, Jin J, Yu XF.

Oncol Res. 2013;20(8):359-68. doi: 10.3727/096504013X13657689382932.

PMID:
23924856
16.

Novel target genes responsive to the anti-growth activity of triptolide in endometrial and ovarian cancer cells.

Li H, Takai N, Yuge A, Furukawa Y, Tsuno A, Tsukamoto Y, Kong S, Moriyama M, Narahara H.

Cancer Lett. 2010 Nov 28;297(2):198-206. doi: 10.1016/j.canlet.2010.05.012. Epub 2010 Jun 14.

PMID:
20547442
17.

Preferential eradication of acute myelogenous leukemia stem cells by fenretinide.

Zhang H, Mi JQ, Fang H, Wang Z, Wang C, Wu L, Zhang B, Minden M, Yang WT, Wang HW, Li JM, Xi XD, Chen SJ, Zhang J, Chen Z, Wang KK.

Proc Natl Acad Sci U S A. 2013 Apr 2;110(14):5606-11. doi: 10.1073/pnas.1302352110. Epub 2013 Mar 19.

18.

Resistance of leukemic stem-like cells in AML cell line KG1a to natural killer cell-mediated cytotoxicity.

She M, Niu X, Chen X, Li J, Zhou M, He Y, Le Y, Guo K.

Cancer Lett. 2012 May 28;318(2):173-9. doi: 10.1016/j.canlet.2011.12.017. Epub 2011 Dec 21.

PMID:
22198207
19.

Preferential induction of apoptosis for primary human leukemic stem cells.

Guzman ML, Swiderski CF, Howard DS, Grimes BA, Rossi RM, Szilvassy SJ, Jordan CT.

Proc Natl Acad Sci U S A. 2002 Dec 10;99(25):16220-5. Epub 2002 Nov 25.

20.

Raman spectrum reveals the cell cycle arrest of Triptolide-induced leukemic T-lymphocytes apoptosis.

Zhang D, Feng Y, Zhang Q, Su X, Lu X, Liu S, Zhong L.

Spectrochim Acta A Mol Biomol Spectrosc. 2015 Apr 15;141:216-22. doi: 10.1016/j.saa.2015.01.037. Epub 2015 Feb 3.

PMID:
25681805

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