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Items: 1 to 20 of 111

1.

FGFR1-WNT-TGF-β signaling in prostate cancer mouse models recapitulates human reactive stroma.

Carstens JL, Shahi P, Van Tsang S, Smith B, Creighton CJ, Zhang Y, Seamans A, Seethammagari M, Vedula I, Levitt JM, Ittmann MM, Rowley DR, Spencer DM.

Cancer Res. 2014 Jan 15;74(2):609-20. doi: 10.1158/0008-5472.CAN-13-1093. Epub 2013 Dec 4.

2.

Stromal transforming growth factor-beta signaling mediates prostatic response to androgen ablation by paracrine Wnt activity.

Placencio VR, Sharif-Afshar AR, Li X, Huang H, Uwamariya C, Neilson EG, Shen MM, Matusik RJ, Hayward SW, Bhowmick NA.

Cancer Res. 2008 Jun 15;68(12):4709-18. doi: 10.1158/0008-5472.CAN-07-6289.

3.

Prostate tumor progression is mediated by a paracrine TGF-beta/Wnt3a signaling axis.

Li X, Placencio V, Iturregui JM, Uwamariya C, Sharif-Afshar AR, Koyama T, Hayward SW, Bhowmick NA.

Oncogene. 2008 Nov 27;27(56):7118-30. doi: 10.1038/onc.2008.293. Epub 2008 Aug 25.

4.

Fibroblast growth factor-2 mediates transforming growth factor-beta action in prostate cancer reactive stroma.

Yang F, Strand DW, Rowley DR.

Oncogene. 2008 Jan 17;27(4):450-9. Epub 2007 Jul 16.

PMID:
17637743
5.

Epithelial Hic-5/ARA55 expression contributes to prostate tumorigenesis and castrate responsiveness.

Li X, Martinez-Ferrer M, Botta V, Uwamariya C, Banerjee J, Bhowmick NA.

Oncogene. 2011 Jan 13;30(2):167-77. doi: 10.1038/onc.2010.400. Epub 2010 Sep 6.

6.

Reactive stroma in human prostate cancer: induction of myofibroblast phenotype and extracellular matrix remodeling.

Tuxhorn JA, Ayala GE, Smith MJ, Smith VC, Dang TD, Rowley DR.

Clin Cancer Res. 2002 Sep;8(9):2912-23.

7.

Stromal expression of connective tissue growth factor promotes angiogenesis and prostate cancer tumorigenesis.

Yang F, Tuxhorn JA, Ressler SJ, McAlhany SJ, Dang TD, Rowley DR.

Cancer Res. 2005 Oct 1;65(19):8887-95.

8.

Lack of transforming growth factor-β signaling promotes collective cancer cell invasion through tumor-stromal crosstalk.

Matise LA, Palmer TD, Ashby WJ, Nashabi A, Chytil A, Aakre M, Pickup MW, Gorska AE, Zijlstra A, Moses HL.

Breast Cancer Res. 2012 Jul 2;14(4):R98. doi: 10.1186/bcr3217.

9.

Altered TGF-β signaling in a subpopulation of human stromal cells promotes prostatic carcinogenesis.

Franco OE, Jiang M, Strand DW, Peacock J, Fernandez S, Jackson RS 2nd, Revelo MP, Bhowmick NA, Hayward SW.

Cancer Res. 2011 Feb 15;71(4):1272-81. doi: 10.1158/0008-5472.CAN-10-3142. Epub 2011 Feb 8.

10.

Transcriptional cooperation between the transforming growth factor-beta and Wnt pathways in mammary and intestinal tumorigenesis.

Labbé E, Lock L, Letamendia A, Gorska AE, Gryfe R, Gallinger S, Moses HL, Attisano L.

Cancer Res. 2007 Jan 1;67(1):75-84.

11.

Promotion of angiogenesis by ps20 in the differential reactive stroma prostate cancer xenograft model.

McAlhany SJ, Ressler SJ, Larsen M, Tuxhorn JA, Yang F, Dang TD, Rowley DR.

Cancer Res. 2003 Sep 15;63(18):5859-65.

12.
13.

Wnt/β-catenin activation promotes prostate tumor progression in a mouse model.

Yu X, Wang Y, DeGraff DJ, Wills ML, Matusik RJ.

Oncogene. 2011 Apr 21;30(16):1868-79. doi: 10.1038/onc.2010.560. Epub 2010 Dec 13.

14.

Dysfunctional transforming growth factor-beta receptor II accelerates prostate tumorigenesis in the TRAMP mouse model.

Pu H, Collazo J, Jones E, Gayheart D, Sakamoto S, Vogt A, Mitchell B, Kyprianou N.

Cancer Res. 2009 Sep 15;69(18):7366-74. doi: 10.1158/0008-5472.CAN-09-0758. Epub 2009 Sep 8.

15.

Stromal activation associated with development of prostate cancer in prostate-targeted fibroblast growth factor 8b transgenic mice.

Elo TD, Valve EM, Seppänen JA, Vuorikoski HJ, Mäkelä SI, Poutanen M, Kujala PM, Härkönen PL.

Neoplasia. 2010 Nov;12(11):915-27.

16.

Cross-talk between paracrine-acting cytokine and chemokine pathways promotes malignancy in benign human prostatic epithelium.

Ao M, Franco OE, Park D, Raman D, Williams K, Hayward SW.

Cancer Res. 2007 May 1;67(9):4244-53.

17.

Genes upregulated in prostate cancer reactive stroma promote prostate cancer progression in vivo.

Dakhova O, Rowley D, Ittmann M.

Clin Cancer Res. 2014 Jan 1;20(1):100-9. doi: 10.1158/1078-0432.CCR-13-1184. Epub 2013 Oct 22.

18.

Androgen signaling is a confounding factor for β-catenin-mediated prostate tumorigenesis.

Lee SH, Luong R, Johnson DT, Cunha GR, Rivina L, Gonzalgo ML, Sun Z.

Oncogene. 2016 Feb 11;35(6):702-14. doi: 10.1038/onc.2015.117. Epub 2015 Apr 20.

19.

Loss of TGF-β responsiveness in prostate stromal cells alters chemokine levels and facilitates the development of mixed osteoblastic/osteolytic bone lesions.

Li X, Sterling JA, Fan KH, Vessella RL, Shyr Y, Hayward SW, Matrisian LM, Bhowmick NA.

Mol Cancer Res. 2012 Apr;10(4):494-503. doi: 10.1158/1541-7786.MCR-11-0506. Epub 2012 Jan 30.

20.

Identification of SFRP1 as a candidate mediator of stromal-to-epithelial signaling in prostate cancer.

Joesting MS, Perrin S, Elenbaas B, Fawell SE, Rubin JS, Franco OE, Hayward SW, Cunha GR, Marker PC.

Cancer Res. 2005 Nov 15;65(22):10423-30.

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