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Items: 1 to 20 of 203

1.

OK-432 synergizes with IFN-γ to confer dendritic cells with enhanced antitumor immunity.

Pan K, Lv L, Zheng HX, Zhao JJ, Pan QZ, Li JJ, Weng DS, Wang DD, Jiang SS, Chang AE, Li Q, Xia JC.

Immunol Cell Biol. 2014 Mar;92(3):263-74. doi: 10.1038/icb.2013.87. Epub 2013 Dec 3.

PMID:
24296809
2.

Streptococcal preparation OK-432: a new maturation factor of monocyte-derived dendritic cells for clinical use.

Kuroki H, Morisaki T, Matsumoto K, Onishi H, Baba E, Tanaka M, Katano M.

Cancer Immunol Immunother. 2003 Sep;52(9):561-8.

PMID:
14627128
3.

Generation of mature dendritic cells fully capable of T helper type 1 polarization using OK-432 combined with prostaglandin E(2).

Sato M, Takayama T, Tanaka H, Konishi J, Suzuki T, Kaiga T, Tahara H.

Cancer Sci. 2003 Dec;94(12):1091-8.

4.

Streptococcal preparation OK432 promotes functional maturation of human monocyte-derived dendritic cells.

Itoh T, Ueda Y, Okugawa K, Fujiwara H, Fuji N, Yamashita T, Fujiki H, Harada S, Yoshimura T, Yamagishi H.

Cancer Immunol Immunother. 2003 Apr;52(4):207-14. Epub 2003 Feb 25.

PMID:
12669245
5.

Effective strategy of dendritic cell-based immunotherapy for advanced tumor-bearing hosts: the critical role of Th1-dominant immunity.

Mashino K, Sadanaga N, Tanaka F, Ohta M, Yamaguchi H, Mori M.

Mol Cancer Ther. 2002 Aug;1(10):785-94.

6.
7.

Streptococcal preparation OK-432 promotes fusion efficiency and enhances induction of antigen-specific CTL by fusions of dendritic cells and colorectal cancer cells.

Koido S, Hara E, Homma S, Torii A, Mitsunaga M, Yanagisawa S, Toyama Y, Kawahara H, Watanabe M, Yoshida S, Kobayashi S, Yanaga K, Fujise K, Tajiri H.

J Immunol. 2007 Jan 1;178(1):613-22.

8.

Uncarinic acid C plus IFN-γ generates monocyte-derived dendritic cells and induces a potent Th1 polarization with capacity to migrate.

Bae WK, Umeyama A, Chung IJ, Lee JJ, Takei M.

Cell Immunol. 2010;266(1):104-10. doi: 10.1016/j.cellimm.2010.09.004. Epub 2010 Sep 18.

PMID:
20933226
9.

Expression of toll-like receptor 4 on dendritic cells is significant for anticancer effect of dendritic cell-based immunotherapy in combination with an active component of OK-432, a streptococcal preparation.

Okamoto M, Furuichi S, Nishioka Y, Oshikawa T, Tano T, Ahmed SU, Takeda K, Akira S, Ryoma Y, Moriya Y, Saito M, Sone S, Sato M.

Cancer Res. 2004 Aug 1;64(15):5461-70.

10.

The pivotal role of p38 and NF-kappaB signal pathways in the maturation of human monocyte-derived dendritic cells stimulated by streptococcal agent OK-432.

Pan K, Wang H, Liu WL, Zhang HK, Zhou J, Li JJ, Weng DS, Huang W, Sun JC, Liang XT, Xia JC.

Immunobiology. 2009;214(5):350-8. doi: 10.1016/j.imbio.2008.10.008. Epub 2008 Dec 20.

PMID:
19362680
11.

Mature dendritic cells generated from patient-derived peripheral blood monocytes in one-step culture using streptococcal preparation OK-432 exert an enhanced antigen-presenting capacity.

Naito K, Ueda Y, Itoh T, Fuji N, Shimizu K, Yano Y, Yamamoto Y, Imura K, Kohara J, Iwamoto A, Shiozaki A, Tamai H, Shimizu T, Mazda O, Yamagishi H.

Int J Oncol. 2006 Jun;28(6):1481-9.

PMID:
16685449
12.

Improved efficacy of therapeutic vaccination with dendritic cells pulsed with tumor cell lysate against hepatocellular carcinoma by introduction of 2 tandem repeats of microbial HSP70 peptide epitope 407-426 and OK-432.

Ge C, Xing Y, Wang Q, Xiao W, Lu Y, Hu X, Gao Z, Xu M, Ma Y, Cao R, Liu J.

Int Immunopharmacol. 2011 Dec;11(12):2200-7. doi: 10.1016/j.intimp.2011.10.001. Epub 2011 Oct 18.

PMID:
22015603
14.
15.

A bacterial flagellin in combination with proinflammatory cytokines activates human monocyte-derived dendritic cells to generate cytotoxic T lymphocytes having increased homing signals to cancer.

Hong CY, Kim SY, Lee HJ, Lee SE, Lim SC, Rhee JH, Lee JJ.

J Immunother. 2014 Jan;37(1):16-25. doi: 10.1097/CJI.0000000000000008.

PMID:
24316552
16.

Cytokine-inducing activity and antitumor effect of a liposome-incorporated interferon-gamma-inducing molecule derived from OK-432, a streptococcal preparation.

Okamoto M, Gohda H, Ohe G, Yoshida H, Matsuno T, Saito M, Sato M.

J Immunother. 2000 Jan;23(1):94-103.

PMID:
10687142
17.

Streptococcal preparation OK-432 promotes the capacity of dendritic cells (DCs) to prime carcinoembryonic antigen (CEA)-specific cytotoxic T lymphocyte responses induced with genetically modified DCs that express CEA.

Ojima T, Iwahashi M, Nakamura M, Matsuda K, Nakamori M, Ueda K, Naka T, Katsuda M, Miyazawa M, Iida T, Yamaue H.

Int J Oncol. 2008 Feb;32(2):459-66.

PMID:
18202769
18.

Induction of Th1-type cytokines by lipoteichoic acid-related preparation isolated from OK-432, a penicillin-killed streptococcal agent.

Okamoto M, Ohe G, Oshikawa T, Nishikawa H, Furuichi S, Yoshida H, Matsuno T, Saito M, Sato M.

Immunopharmacology. 2000 Sep;49(3):363-76.

PMID:
10996034
19.

IL-4 blocks TH1-polarizing/inflammatory cytokine gene expression during monocyte-derived dendritic cell differentiation through histone hypoacetylation.

López-Bravo M, Minguito de la Escalera M, Domínguez PM, González-Cintado L, del Fresno C, Martín P, Martínez del Hoyo G, Ardavín C.

J Allergy Clin Immunol. 2013 Dec;132(6):1409-19. doi: 10.1016/j.jaci.2013.08.039. Epub 2013 Oct 17.

PMID:
24139608
20.

Triggering of NF-κB in cytokine-matured human DCs generates superior DCs for T-cell priming in cancer immunotherapy.

Pfeiffer IA, Hoyer S, Gerer KF, Voll RE, Knippertz I, Gückel E, Schuler G, Schaft N, Dörrie J.

Eur J Immunol. 2014 Nov;44(11):3413-28. doi: 10.1002/eji.201344417. Epub 2014 Sep 16.

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