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Items: 1 to 20 of 102

1.

Genipin induces cyclooxygenase-2 expression via NADPH oxidase, MAPKs, AP-1, and NF-κB in RAW 264.7 cells.

Khanal T, Kim HG, Do MT, Choi JH, Chung YC, Kim HS, Park YJ, Jeong TC, Jeong HG.

Food Chem Toxicol. 2014 Feb;64:126-34. doi: 10.1016/j.fct.2013.11.035. Epub 2013 Dec 1.

PMID:
24296130
2.

Propionibacterium acnes-induced iNOS and COX-2 protein expression via ROS-dependent NF-κB and AP-1 activation in macrophages.

Tsai HH, Lee WR, Wang PH, Cheng KT, Chen YC, Shen SC.

J Dermatol Sci. 2013 Feb;69(2):122-31. doi: 10.1016/j.jdermsci.2012.10.009. Epub 2012 Oct 24.

PMID:
23178030
3.

Endosulfan induces COX-2 expression via NADPH oxidase and the ROS, MAPK, and Akt pathways.

Kim HG, Kim YR, Park JH, Khanal T, Choi JH, Do MT, Jin SW, Han EH, Chung YH, Jeong HG.

Arch Toxicol. 2015 Nov;89(11):2039-50. doi: 10.1007/s00204-014-1359-7. Epub 2014 Sep 9.

PMID:
25199686
4.

Enterovirus 71 induces COX-2 expression via MAPKs, NF-kappaB, and AP-1 in SK-N-SH cells: Role of PGE(2) in viral replication.

Tung WH, Hsieh HL, Yang CM.

Cell Signal. 2010 Feb;22(2):234-46. doi: 10.1016/j.cellsig.2009.09.018. Epub 2009 Oct 1.

PMID:
19800403
5.

Risk assessment of tetrabromobisphenol A on cyclooxygenase-2 expression via MAP kinase/NF-kappaB/AP-1 signaling pathways in murine macrophages.

Han EH, Park JH, Kang KW, Jeong TC, Kim HS, Jeong HG.

J Toxicol Environ Health A. 2009;72(21-22):1431-8. doi: 10.1080/15287390903212873.

PMID:
20077215
6.

Benzo[a]pyrene diol-epoxide (B[a]PDE) upregulates COX-2 expression through MAPKs/AP-1 and IKKbeta/NF-kappaB in mouse epidermal Cl41 cells.

Ouyang W, Ma Q, Li J, Zhang D, Ding J, Huang Y, Xing MM, Huang C.

Mol Carcinog. 2007 Jan;46(1):32-41.

PMID:
16921490
7.

Humic acid in drinking well water induces inflammation through reactive oxygen species generation and activation of nuclear factor-κB/activator protein-1 signaling pathways: a possible role in atherosclerosis.

Hseu YC, Senthil Kumar KJ, Chen CS, Cho HJ, Lin SW, Shen PC, Lin CW, Lu FJ, Yang HL.

Toxicol Appl Pharmacol. 2014 Jan 15;274(2):249-62. doi: 10.1016/j.taap.2013.11.002. Epub 2013 Nov 12.

PMID:
24239652
8.

PAR1-dependent COX-2/PGE2 production contributes to cell proliferation via EP2 receptors in primary human cardiomyocytes.

Chien PT, Hsieh HL, Chi PL, Yang CM.

Br J Pharmacol. 2014 Oct;171(19):4504-19. doi: 10.1111/bph.12794. Epub 2014 Sep 5.

9.

Geniposide suppresses LPS-induced nitric oxide, PGE2 and inflammatory cytokine by downregulating NF-κB, MAPK and AP-1 signaling pathways in macrophages.

Shi Q, Cao J, Fang L, Zhao H, Liu Z, Ran J, Zheng X, Li X, Zhou Y, Ge D, Zhang H, Wang L, Ran Y, Fu J.

Int Immunopharmacol. 2014 Jun;20(2):298-306. doi: 10.1016/j.intimp.2014.04.004. Epub 2014 Apr 13.

PMID:
24735815
10.

Melamine activates NFκB/COX-2/PGE2 pathway and increases NADPH oxidase-dependent ROS production in macrophages and human embryonic kidney cells.

Kuo FC, Tseng YT, Wu SR, Wu MT, Lo YC.

Toxicol In Vitro. 2013 Sep;27(6):1603-11. doi: 10.1016/j.tiv.2013.04.011. Epub 2013 Apr 30.

PMID:
23643631
11.

Quercetin disrupts tyrosine-phosphorylated phosphatidylinositol 3-kinase and myeloid differentiation factor-88 association, and inhibits MAPK/AP-1 and IKK/NF-κB-induced inflammatory mediators production in RAW 264.7 cells.

Endale M, Park SC, Kim S, Kim SH, Yang Y, Cho JY, Rhee MH.

Immunobiology. 2013 Dec;218(12):1452-67. doi: 10.1016/j.imbio.2013.04.019. Epub 2013 May 9.

PMID:
23735482
12.

Cadmium induces matrix metalloproteinase-9 expression via ROS-dependent EGFR, NF-кB, and AP-1 pathways in human endothelial cells.

Lian S, Xia Y, Khoi PN, Ung TT, Yoon HJ, Kim NH, Kim KK, Jung YD.

Toxicology. 2015 Dec 2;338:104-16. doi: 10.1016/j.tox.2015.10.008. Epub 2015 Nov 11.

PMID:
26514923
13.

Eupafolin inhibits PGE2 production and COX2 expression in LPS-stimulated human dermal fibroblasts by blocking JNK/AP-1 and Nox2/p47(phox) pathway.

Tsai MH, Lin ZC, Liang CJ, Yen FL, Chiang YC, Lee CW.

Toxicol Appl Pharmacol. 2014 Sep 1;279(2):240-51. doi: 10.1016/j.taap.2014.06.012. Epub 2014 Jun 23.

PMID:
24967690
14.

Phellinus linteus inhibits inflammatory mediators by suppressing redox-based NF-kappaB and MAPKs activation in lipopolysaccharide-induced RAW 264.7 macrophage.

Kim HG, Yoon DH, Lee WH, Han SK, Shrestha B, Kim CH, Lim MH, Chang W, Lim S, Choi S, Song WO, Sung JM, Hwang KC, Kim TW.

J Ethnopharmacol. 2007 Dec 3;114(3):307-15. Epub 2007 Aug 19.

PMID:
17936530
15.
16.

Piperine inhibits PMA-induced cyclooxygenase-2 expression through downregulating NF-κB, C/EBP and AP-1 signaling pathways in murine macrophages.

Kim HG, Han EH, Jang WS, Choi JH, Khanal T, Park BH, Tran TP, Chung YC, Jeong HG.

Food Chem Toxicol. 2012 Jul;50(7):2342-8. doi: 10.1016/j.fct.2012.04.024. Epub 2012 Apr 21.

PMID:
22542552
17.

Alantolactone suppresses inducible nitric oxide synthase and cyclooxygenase-2 expression by down-regulating NF-κB, MAPK and AP-1 via the MyD88 signaling pathway in LPS-activated RAW 264.7 cells.

Chun J, Choi RJ, Khan S, Lee DS, Kim YC, Nam YJ, Lee DU, Kim YS.

Int Immunopharmacol. 2012 Dec;14(4):375-83. doi: 10.1016/j.intimp.2012.08.011. Epub 2012 Aug 28.

PMID:
22940184
18.

EV71 induces COX-2 expression via c-Src/PDGFR/PI3K/Akt/p42/p44 MAPK/AP-1 and NF-kappaB in rat brain astrocytes.

Tung WH, Lee IT, Hsieh HL, Yang CM.

J Cell Physiol. 2010 Aug;224(2):376-86. doi: 10.1002/jcp.22133.

PMID:
20333648
19.

Suppression of iNOS and COX-2 expression by flavokawain A via blockade of NF-κB and AP-1 activation in RAW 264.7 macrophages.

Kwon DJ, Ju SM, Youn GS, Choi SY, Park J.

Food Chem Toxicol. 2013 Aug;58:479-86. doi: 10.1016/j.fct.2013.05.031. Epub 2013 May 28.

PMID:
23727179

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