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Items: 1 to 20 of 101

1.

A small-molecule inducer of PDX1 expression identified by high-throughput screening.

Yuan Y, Hartland K, Boskovic Z, Wang Y, Walpita D, Lysy PA, Zhong C, Young DW, Kim YK, Tolliday NJ, Sokal EM, Schreiber SL, Wagner BK.

Chem Biol. 2013 Dec 19;20(12):1513-22. doi: 10.1016/j.chembiol.2013.10.013. Epub 2013 Nov 27. Erratum in: Chem Biol. 2014 Feb 20;21(2):306.

2.

The PDX1 homeodomain transcription factor negatively regulates the pancreatic ductal cell-specific keratin 19 promoter.

Deramaudt TB, Sachdeva MM, Wescott MP, Chen Y, Stoffers DA, Rustgi AK.

J Biol Chem. 2006 Dec 15;281(50):38385-95. Epub 2006 Oct 20.

3.

Sequential introduction and dosage balance of defined transcription factors affect reprogramming efficiency from pancreatic duct cells into insulin-producing cells.

Miyashita K, Miyatsuka T, Matsuoka TA, Sasaki S, Takebe S, Yasuda T, Watada H, Kaneto H, Shimomura I.

Biochem Biophys Res Commun. 2014 Feb 21;444(4):514-9. doi: 10.1016/j.bbrc.2014.01.083. Epub 2014 Jan 25.

PMID:
24472553
4.

Negative regulation of c-Myc transcription by pancreas duodenum homeobox-1.

Chen L, Yan HX, Chen J, Yang W, Liu Q, Zhai B, Cao HF, Liu SQ, Wu MC, Wang HY.

Endocrinology. 2007 May;148(5):2168-80. Epub 2007 Feb 22.

PMID:
17317781
5.

The homeodomain-interacting protein kinase 2 regulates insulin promoter factor-1/pancreatic duodenal homeobox-1 transcriptional activity.

Boucher MJ, Simoneau M, Edlund H.

Endocrinology. 2009 Jan;150(1):87-97. doi: 10.1210/en.2007-0865. Epub 2008 Sep 4.

PMID:
18772243
6.

A multi-parameter, high-content, high-throughput screening platform to identify natural compounds that modulate insulin and Pdx1 expression.

Hill JA, Szabat M, Hoesli CA, Gage BK, Yang YH, Williams DE, Riedel MJ, Luciani DS, Kalynyak TB, Tsai K, Ao Z, Andersen RJ, Warnock GL, Piret JM, Kieffer TJ, Johnson JD.

PLoS One. 2010 Sep 23;5(9):e12958. doi: 10.1371/journal.pone.0012958.

7.

The effect of overexpression of Pdx1 and Foxa2 on the differentiation of human embryonic stem cells into pancreatic cells.

Lavon N, Yanuka O, Benvenisty N.

Stem Cells. 2006 Aug;24(8):1923-30. Epub 2006 May 4.

8.

The Krüppel-like protein Gli-similar 3 (Glis3) functions as a key regulator of insulin transcription.

ZeRuth GT, Takeda Y, Jetten AM.

Mol Endocrinol. 2013 Oct;27(10):1692-705. doi: 10.1210/me.2013-1117. Epub 2013 Aug 8.

9.

Pdx1 expression in pancreatic precursor lesions and neoplasms.

Park JY, Hong SM, Klimstra DS, Goggins MG, Maitra A, Hruban RH.

Appl Immunohistochem Mol Morphol. 2011 Oct;19(5):444-9. doi: 10.1097/PAI.0b013e318206d958.

10.

Reprogramming of pancreatic exocrine cells towards a beta (β) cell character using Pdx1, Ngn3 and MafA.

Akinci E, Banga A, Greder LV, Dutton JR, Slack JM.

Biochem J. 2012 Mar 15;442(3):539-50. doi: 10.1042/BJ20111678.

11.

Reprogramming liver-stem WB cells into functional insulin-producing cells by persistent expression of Pdx1- and Pdx1-VP16 mediated by lentiviral vectors.

Tang DQ, Lu S, Sun YP, Rodrigues E, Chou W, Yang C, Cao LZ, Chang LJ, Yang LJ.

Lab Invest. 2006 Jan;86(1):83-93.

12.

Maturation of adult beta-cells revealed using a Pdx1/insulin dual-reporter lentivirus.

Szabat M, Luciani DS, Piret JM, Johnson JD.

Endocrinology. 2009 Apr;150(4):1627-35. doi: 10.1210/en.2008-1224. Epub 2008 Dec 18.

PMID:
19095744
13.

MafA and MafB regulate Pdx1 transcription through the Area II control region in pancreatic beta cells.

Vanhoose AM, Samaras S, Artner I, Henderson E, Hang Y, Stein R.

J Biol Chem. 2008 Aug 15;283(33):22612-9. doi: 10.1074/jbc.M802902200. Epub 2008 Jun 3.

14.

PDX1- and NGN3-mediated in vitro reprogramming of human bone marrow-derived mesenchymal stromal cells into pancreatic endocrine lineages.

Limbert C, Päth G, Ebert R, Rothhammer V, Kassem M, Jakob F, Seufert J.

Cytotherapy. 2011 Aug;13(7):802-13. doi: 10.3109/14653249.2011.571248. Epub 2011 Apr 21.

PMID:
21506889
15.

Pdx1 regulates pancreas tubulogenesis and E-cadherin expression.

Marty-Santos L, Cleaver O.

Development. 2016 Jan 1;143(1):101-12. doi: 10.1242/dev.126755. Epub 2015 Dec 10. Erratum in: Development. 2016 Mar 15;143(6):1056.

16.

Bile duct expression of pancreatic and duodenal homeobox 1 in perihilar cholangiocarcinogenesis.

Igarashi S, Matsubara T, Harada K, Ikeda H, Sato Y, Sasaki M, Matsui O, Nakanuma Y.

Histopathology. 2012 Aug;61(2):266-76. doi: 10.1111/j.1365-2559.2012.04218.x. Epub 2012 May 17.

PMID:
22594685
17.

Insulin but not glucagon gene is silenced in human pancreas-derived mesenchymal stem cells.

Wilson LM, Wong SH, Yu N, Geras-Raaka E, Raaka BM, Gershengorn MC.

Stem Cells. 2009 Nov;27(11):2703-11. doi: 10.1002/stem.229.

18.

Programming of human umbilical cord mesenchymal stem cells in vitro to promote pancreatic gene expression.

Wang H, Yang Y, Ho G, Lin X, Wu W, Li W, Lin L, Feng X, Huo X, Jiang J, Liu X, Huang T, Wei C, Ma L.

Mol Med Rep. 2013 Sep;8(3):769-74. doi: 10.3892/mmr.2013.1598. Epub 2013 Jul 23.

PMID:
23900717
19.

PDX1, a cellular homeoprotein, binds to and regulates the activity of human cytomegalovirus immediate early promoter.

Chao SH, Harada JN, Hyndman F, Gao X, Nelson CG, Chanda SK, Caldwell JS.

J Biol Chem. 2004 Apr 16;279(16):16111-20. Epub 2004 Feb 5.

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