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Items: 1 to 20 of 99


An IKKα-nucleophosmin axis utilizes inflammatory signaling to promote genome integrity.

Xia X, Liu S, Xiao Z, Zhu F, Song NY, Zhou M, Liu B, Shen J, Nagashima K, Veenstra TD, Burkett S, Datla M, Willette-Brown J, Shen H, Hu Y.

Cell Rep. 2013 Dec 12;5(5):1243-55. doi: 10.1016/j.celrep.2013.10.046. Epub 2013 Nov 27.


Temporal and spatial control of nucleophosmin by the Ran-Crm1 complex in centrosome duplication.

Wang W, Budhu A, Forgues M, Wang XW.

Nat Cell Biol. 2005 Aug;7(8):823-30. Epub 2005 Jul 24.


Cdk2 and Cdk4 regulate the centrosome cycle and are critical mediators of centrosome amplification in p53-null cells.

Adon AM, Zeng X, Harrison MK, Sannem S, Kiyokawa H, Kaldis P, Saavedra HI.

Mol Cell Biol. 2010 Feb;30(3):694-710. doi: 10.1128/MCB.00253-09. Epub 2009 Nov 23.


Interaction between ROCK II and nucleophosmin/B23 in the regulation of centrosome duplication.

Ma Z, Kanai M, Kawamura K, Kaibuchi K, Ye K, Fukasawa K.

Mol Cell Biol. 2006 Dec;26(23):9016-34. Epub 2006 Oct 2.


Critical role of IkappaB kinase alpha in embryonic skin development and skin carcinogenesis.

Zhu F, Park E, Liu B, Xia X, Fischer SM, Hu Y.

Histol Histopathol. 2009 Feb;24(2):265-71. doi: 10.14670/HH-24.265. Review.


Reduction in IkappaB kinase alpha expression promotes the development of skin papillomas and carcinomas.

Park E, Zhu F, Liu B, Xia X, Shen J, Bustos T, Fischer SM, Hu Y.

Cancer Res. 2007 Oct 1;67(19):9158-68.


IKKα promotes intestinal tumorigenesis by limiting recruitment of M1-like polarized myeloid cells.

Göktuna SI, Canli O, Bollrath J, Fingerle AA, Horst D, Diamanti MA, Pallangyo C, Bennecke M, Nebelsiek T, Mankan AK, Lang R, Artis D, Hu Y, Patzelt T, Ruland J, Kirchner T, Taketo MM, Chariot A, Arkan MC, Greten FR.

Cell Rep. 2014 Jun 26;7(6):1914-25. doi: 10.1016/j.celrep.2014.05.006. Epub 2014 May 29.


Nucleophosmin and human cancer.

Lim MJ, Wang XW.

Cancer Detect Prev. 2006;30(6):481-90. Epub 2006 Nov 17. Review.


Specific phosphorylation of nucleophosmin on Thr(199) by cyclin-dependent kinase 2-cyclin E and its role in centrosome duplication.

Tokuyama Y, Horn HF, Kawamura K, Tarapore P, Fukasawa K.

J Biol Chem. 2001 Jun 15;276(24):21529-37. Epub 2001 Feb 27.


LGR5 expression is controled by IKKα in basal cell carcinoma through activating STAT3 signaling pathway.

Jia J, Shi Y, Yan B, Xiao D, Lai W, Pan Y, Jiang Y, Chen L, Mao C, Zhou J, Xi S, Cao Y, Liu S, Tao Y.

Oncotarget. 2016 May 10;7(19):27280-94. doi: 10.18632/oncotarget.8465.


A critical role for I kappaB kinase alpha in the development of human and mouse squamous cell carcinomas.

Liu B, Park E, Zhu F, Bustos T, Liu J, Shen J, Fischer SM, Hu Y.

Proc Natl Acad Sci U S A. 2006 Nov 14;103(46):17202-7. Epub 2006 Nov 1.


Progression elevated gene-3 (PEG-3) induces pleiotropic effects on tumor progression: modulation of genomic stability and invasion.

Emdad L, Sarkar D, Su ZZ, Boukerche H, Bar-Eli M, Fisher PB.

J Cell Physiol. 2005 Jan;202(1):135-46.


Hepatitis B virus X protein induces IKKα nuclear translocation via Akt-dependent phosphorylation to promote the motility of hepatocarcinoma cells.

Huang WC, Chen WS, Chen YJ, Wang LY, Hsu SC, Chen CC, Hung MC.

J Cell Physiol. 2012 Apr;227(4):1446-54. doi: 10.1002/jcp.22860.


Role of IKKα in skin squamous cell carcinomas.

Park E, Liu B, Xia X, Zhu F, Jami WB, Hu Y.

Future Oncol. 2011 Jan;7(1):123-34. doi: 10.2217/fon.10.166. Review.


Functional relationship among PLK2, PLK4 and ROCK2 to induce centrosome amplification.

Ling H, Hanashiro K, Luong TH, Benavides L, Fukasawa K.

Cell Cycle. 2015;14(4):544-53. doi: 10.4161/15384101.2014.989121.


Nucleophosmin/B23 activates Aurora A at the centrosome through phosphorylation of serine 89.

Reboutier D, Troadec MB, Cremet JY, Fukasawa K, Prigent C.

J Cell Biol. 2012 Apr 2;197(1):19-26. doi: 10.1083/jcb.201107134. Epub 2012 Mar 26.


Nucleophosmin/B23 is a target of CDK2/cyclin E in centrosome duplication.

Okuda M, Horn HF, Tarapore P, Tokuyama Y, Smulian AG, Chan PK, Knudsen ES, Hofmann IA, Snyder JD, Bove KE, Fukasawa K.

Cell. 2000 Sep 29;103(1):127-40.


The pivotal role of IKKα in the development of spontaneous lung squamous cell carcinomas.

Xiao Z, Jiang Q, Willette-Brown J, Xi S, Zhu F, Burkett S, Back T, Song NY, Datla M, Sun Z, Goldszmid R, Lin F, Cohoon T, Pike K, Wu X, Schrump DS, Wong KK, Young HA, Trinchieri G, Wiltrout RH, Hu Y.

Cancer Cell. 2013 Apr 15;23(4):527-40. doi: 10.1016/j.ccr.2013.03.009.


The role of nucleophosmin in centrosome duplication.

Okuda M.

Oncogene. 2002 Sep 9;21(40):6170-4. Review.

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