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Items: 1 to 20 of 110

1.

Quantifying rare, deleterious variation in 12 human cytochrome P450 drug-metabolism genes in a large-scale exome dataset.

Gordon AS, Tabor HK, Johnson AD, Snively BM, Assimes TL, Auer PL, Ioannidis JP, Peters U, Robinson JG, Sucheston LE, Wang D, Sotoodehnia N, Rotter JI, Psaty BM, Jackson RD, Herrington DM, O'Donnell CJ, Reiner AP, Rich SS, Rieder MJ, Bamshad MJ, Nickerson DA; NHLBI GO Exome Sequencing Project.

Hum Mol Genet. 2014 Apr 15;23(8):1957-63. doi: 10.1093/hmg/ddt588. Epub 2013 Nov 26.

2.

Polymorphism of human cytochrome P450 enzymes and its clinical impact.

Zhou SF, Liu JP, Chowbay B.

Drug Metab Rev. 2009;41(2):89-295. doi: 10.1080/03602530902843483. Review.

PMID:
19514967
3.

Genetic variation in eleven phase I drug metabolism genes in an ethnically diverse population.

Solus JF, Arietta BJ, Harris JR, Sexton DP, Steward JQ, McMunn C, Ihrie P, Mehall JM, Edwards TL, Dawson EP.

Pharmacogenomics. 2004 Oct;5(7):895-931.

PMID:
15469410
4.

Worldwide Distribution of Cytochrome P450 Alleles: A Meta-analysis of Population-scale Sequencing Projects.

Zhou Y, Ingelman-Sundberg M, Lauschke VM.

Clin Pharmacol Ther. 2017 Oct;102(4):688-700. doi: 10.1002/cpt.690. Epub 2017 May 26.

5.

Allele frequency differences of cytochrome P450 polymorphisms in a sample of New Zealand Māori.

Lea RA, Roberts RL, Green MR, Kennedy MA, Chambers GK.

N Z Med J. 2008 Apr 18;121(1272):33-7.

PMID:
18425152
6.

Global pharmacogenetics: genetic substructure of Eurasian populations and its effect on variants of drug-metabolizing enzymes.

Makeeva O, Stepanov V, Puzyrev V, Goldstein DB, Grossman I.

Pharmacogenomics. 2008 Jul;9(7):847-68. doi: 10.2217/14622416.9.7.847.

PMID:
18597650
7.
8.
9.

Pharmacogenetics of the cytochromes P450.

Daly AK.

Curr Top Med Chem. 2004;4(16):1733-44. Review.

PMID:
15579105
11.

African Genetic Diversity: Implications for Cytochrome P450-mediated Drug Metabolism and Drug Development.

Rajman I, Knapp L, Morgan T, Masimirembwa C.

EBioMedicine. 2017 Mar;17:67-74. doi: 10.1016/j.ebiom.2017.02.017. Epub 2017 Feb 20.

12.

Identifying drugs needing pharmacogenetic monitoring in a Korean hospital.

Kim YM, Yoo SH, Kang RY, Kim MJ, Bae YY, Lee YK, Jeon SJ, Chon KJ, Shin SM, Kim SG, Park KH, Son IJ.

Am J Health Syst Pharm. 2007 Jan 15;64(2):166-75.

PMID:
17215467
13.

Pharmacogenetics.

Wolf CR, Smith G.

Br Med Bull. 1999;55(2):366-86. Review.

PMID:
10723863
14.

Pharmacogenetics of cytochrome P450 (CYP) in the elderly.

Seripa D, Pilotto A, Panza F, Matera MG, Pilotto A.

Ageing Res Rev. 2010 Oct;9(4):457-74. doi: 10.1016/j.arr.2010.06.001. Epub 2010 Jun 20. Review.

PMID:
20601196
15.

Pharmacogenetics of drug-metabolizing enzymes in Italian populations.

Serpe L, Canaparo R, Scordo MG, Spina E.

Drug Metab Pers Ther. 2015 Jun;30(2):107-20. doi: 10.1515/dmdi-2014-0028. Review.

16.

Characteristics of neutral and deleterious protein-coding variation among individuals and populations.

Fu W, Gittelman RM, Bamshad MJ, Akey JM.

Am J Hum Genet. 2014 Oct 2;95(4):421-36. doi: 10.1016/j.ajhg.2014.09.006.

17.

Influence of cytochrome P450 polymorphisms on drug therapies: pharmacogenetic, pharmacoepigenetic and clinical aspects.

Ingelman-Sundberg M, Sim SC, Gomez A, Rodriguez-Antona C.

Pharmacol Ther. 2007 Dec;116(3):496-526. Epub 2007 Oct 9. Review.

PMID:
18001838
18.

P450 oxidoreductase: genetic polymorphisms and implications for drug metabolism and toxicity.

Hart SN, Zhong XB.

Expert Opin Drug Metab Toxicol. 2008 Apr;4(4):439-52. doi: 10.1517/17425255.4.4.439 . Review.

PMID:
18433346
19.

Genetic polymorphism and toxicology--with emphasis on cytochrome p450.

Johansson I, Ingelman-Sundberg M.

Toxicol Sci. 2011 Mar;120(1):1-13. doi: 10.1093/toxsci/kfq374. Epub 2010 Dec 13. Review.

PMID:
21149643
20.

Considerations for rare variants in drug metabolism genes and the clinical implications.

Drögemöller BI, Wright GE, Warnich L.

Expert Opin Drug Metab Toxicol. 2014 Jun;10(6):873-84. doi: 10.1517/17425255.2014.903239. Epub 2014 Mar 28. Review.

PMID:
24673405

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