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Items: 1 to 20 of 172

1.

Akt2 deficiency protects from acute lung injury via alternative macrophage activation and miR-146a induction in mice.

Vergadi E, Vaporidi K, Theodorakis EE, Doxaki C, Lagoudaki E, Ieronymaki E, Alexaki VI, Helms M, Kondili E, Soennichsen B, Stathopoulos EN, Margioris AN, Georgopoulos D, Tsatsanis C.

J Immunol. 2014 Jan 1;192(1):394-406. doi: 10.4049/jimmunol.1300959. Epub 2013 Nov 25.

2.

Akt2 deficiency as a therapeutic strategy protects against acute lung injury.

Gauna AE, Cha S.

Immunotherapy. 2014;6(4):377-80. doi: 10.2217/imt.14.5.

3.

MiR-127 modulates macrophage polarization and promotes lung inflammation and injury by activating the JNK pathway.

Ying H, Kang Y, Zhang H, Zhao D, Xia J, Lu Z, Wang H, Xu F, Shi L.

J Immunol. 2015 Feb 1;194(3):1239-51. doi: 10.4049/jimmunol.1402088. Epub 2014 Dec 17.

4.

miR-125a-5p regulates differential activation of macrophages and inflammation.

Banerjee S, Cui H, Xie N, Tan Z, Yang S, Icyuz M, Thannickal VJ, Abraham E, Liu G.

J Biol Chem. 2013 Dec 6;288(49):35428-36. doi: 10.1074/jbc.M112.426866. Epub 2013 Oct 22.

5.

MiR-146a modulates macrophage polarization by inhibiting Notch1 pathway in RAW264.7 macrophages.

Huang C, Liu XJ, QunZhou, Xie J, Ma TT, Meng XM, Li J.

Int Immunopharmacol. 2016 Mar;32:46-54. doi: 10.1016/j.intimp.2016.01.009. Epub 2016 Jan 19.

PMID:
26800097
6.

Upregulation of miR-146a contributes to the suppression of inflammatory responses in LPS-induced acute lung injury.

Zeng Z, Gong H, Li Y, Jie K, Ding C, Shao Q, Liu F, Zhan Y, Nie C, Zhu W, Qian K.

Exp Lung Res. 2013 Sep;39(7):275-82. doi: 10.3109/01902148.2013.808285. Epub 2013 Jul 12.

PMID:
23848342
7.

Akt1 and Akt2 protein kinases differentially contribute to macrophage polarization.

Arranz A, Doxaki C, Vergadi E, Martinez de la Torre Y, Vaporidi K, Lagoudaki ED, Ieronymaki E, Androulidaki A, Venihaki M, Margioris AN, Stathopoulos EN, Tsichlis PN, Tsatsanis C.

Proc Natl Acad Sci U S A. 2012 Jun 12;109(24):9517-22. doi: 10.1073/pnas.1119038109. Epub 2012 May 30.

8.

Enforced expression of miR-125b attenuates LPS-induced acute lung injury.

Guo Z, Gu Y, Wang C, Zhang J, Shan S, Gu X, Wang K, Han Y, Ren T.

Immunol Lett. 2014 Nov;162(1 Pt A):18-26. doi: 10.1016/j.imlet.2014.06.008. Epub 2014 Jul 6.

PMID:
25004393
9.

IRF5 regulates lung macrophages M2 polarization during severe acute pancreatitis in vitro.

Sun K, He SB, Qu JG, Dang SC, Chen JX, Gong AH, Xie R, Zhang JX.

World J Gastroenterol. 2016 Nov 14;22(42):9368-9377.

10.

Myocardial injury after ischemia-reperfusion in mice deficient in Akt2 is associated with increased cardiac macrophage density.

Li X, Mikhalkova D, Gao E, Zhang J, Myers V, Zincarelli C, Lei Y, Song J, Koch WJ, Peppel K, Cheung JY, Feldman AM, Chan TO.

Am J Physiol Heart Circ Physiol. 2011 Nov;301(5):H1932-40. doi: 10.1152/ajpheart.00755.2010. Epub 2011 Sep 2.

11.

Macrophage A2A adenosinergic receptor modulates oxygen-induced augmentation of murine lung injury.

Aggarwal NR, D'Alessio FR, Eto Y, Chau E, Avalos C, Waickman AT, Garibaldi BT, Mock JR, Files DC, Sidhaye V, Polotsky VY, Powell J, Horton M, King LS.

Am J Respir Cell Mol Biol. 2013 May;48(5):635-46. doi: 10.1165/rcmb.2012-0351OC.

12.

MiR-146a modulates macrophage polarization in systemic juvenile idiopathic arthritis by targeting INHBA.

Li D, Duan M, Feng Y, Geng L, Li X, Zhang W.

Mol Immunol. 2016 Sep;77:205-12. doi: 10.1016/j.molimm.2016.08.007. Epub 2016 Aug 16.

PMID:
27541693
13.

Induction of IL-4Rα-dependent microRNAs identifies PI3K/Akt signaling as essential for IL-4-driven murine macrophage proliferation in vivo.

Rückerl D, Jenkins SJ, Laqtom NN, Gallagher IJ, Sutherland TE, Duncan S, Buck AH, Allen JE.

Blood. 2012 Sep 13;120(11):2307-16. doi: 10.1182/blood-2012-02-408252. Epub 2012 Aug 1.

14.

Stem cell conditioned medium improves acute lung injury in mice: in vivo evidence for stem cell paracrine action.

Ionescu L, Byrne RN, van Haaften T, Vadivel A, Alphonse RS, Rey-Parra GJ, Weissmann G, Hall A, Eaton F, Thébaud B.

Am J Physiol Lung Cell Mol Physiol. 2012 Dec 1;303(11):L967-77. doi: 10.1152/ajplung.00144.2011. Epub 2012 Sep 28.

15.

[The protective effects of transfected microRNA-146a on mice with sepsis-induced acute lung injury in vivo].

Zhang J, Ding C, Shao Q, Liu F, Zeng Z, Nie C, Qian K.

Zhonghua Wei Zhong Bing Ji Jiu Yi Xue. 2015 Jul;27(7):591-4. doi: 10.3760/cma.j.issn.2095-4352.2015.07.010. Chinese.

16.

Macrophage deficiency of Akt2 reduces atherosclerosis in Ldlr null mice.

Babaev VR, Hebron KE, Wiese CB, Toth CL, Ding L, Zhang Y, May JM, Fazio S, Vickers KC, Linton MF.

J Lipid Res. 2014 Nov;55(11):2296-308. doi: 10.1194/jlr.M050633. Epub 2014 Sep 19.

17.

Macrophage micro-RNA-155 promotes lipopolysaccharide-induced acute lung injury in mice and rats.

Wang W, Liu Z, Su J, Chen WS, Wang XW, Bai SX, Zhang JZ, Yu SQ.

Am J Physiol Lung Cell Mol Physiol. 2016 Aug 1;311(2):L494-506. doi: 10.1152/ajplung.00001.2016. Epub 2016 Jul 1.

PMID:
27371731
18.

Induction of M2 regulatory macrophages through the β2-adrenergic receptor with protection during endotoxemia and acute lung injury.

Grailer JJ, Haggadone MD, Sarma JV, Zetoune FS, Ward PA.

J Innate Immun. 2014;6(5):607-18. doi: 10.1159/000358524. Epub 2014 Mar 14.

19.

MicroRNA 21 is a homeostatic regulator of macrophage polarization and prevents prostaglandin E2-mediated M2 generation.

Wang Z, Brandt S, Medeiros A, Wang S, Wu H, Dent A, Serezani CH.

PLoS One. 2015 Feb 23;10(2):e0115855. doi: 10.1371/journal.pone.0115855. eCollection 2015.

20.

MicroR-146 blocks the activation of M1 macrophage by targeting signal transducer and activator of transcription 1 in hepatic schistosomiasis.

He X, Tang R, Sun Y, Wang YG, Zhen KY, Zhang DM, Pan WQ.

EBioMedicine. 2016 Nov;13:339-347. doi: 10.1016/j.ebiom.2016.10.024. Epub 2016 Oct 19.

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