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Items: 1 to 20 of 84

1.

A map of the PPARα transcription regulatory network for primary human hepatocytes.

McMullen PD, Bhattacharya S, Woods CG, Sun B, Yarborough K, Ross SM, Miller ME, McBride MT, LeCluyse EL, Clewell RA, Andersen ME.

Chem Biol Interact. 2014 Feb 25;209:14-24. doi: 10.1016/j.cbi.2013.11.006. Epub 2013 Nov 22.

2.

Direct transcriptional regulation of human hepatic cytochrome P450 3A4 (CYP3A4) by peroxisome proliferator-activated receptor alpha (PPARα).

Thomas M, Burk O, Klumpp B, Kandel BA, Damm G, Weiss TS, Klein K, Schwab M, Zanger UM.

Mol Pharmacol. 2013 Mar;83(3):709-18. doi: 10.1124/mol.112.082503. Epub 2013 Jan 7.

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Transcription coactivator PBP, the peroxisome proliferator-activated receptor (PPAR)-binding protein, is required for PPARalpha-regulated gene expression in liver.

Jia Y, Qi C, Kashireddi P, Surapureddi S, Zhu YJ, Rao MS, Le Roith D, Chambon P, Gonzalez FJ, Reddy JK.

J Biol Chem. 2004 Jun 4;279(23):24427-34. Epub 2004 Mar 29.

6.

Differential gene expression in mouse primary hepatocytes exposed to the peroxisome proliferator-activated receptor alpha agonists.

Guo L, Fang H, Collins J, Fan XH, Dial S, Wong A, Mehta K, Blann E, Shi L, Tong W, Dragan YP.

BMC Bioinformatics. 2006 Sep 6;7 Suppl 2:S18.

7.

Hepatocyte nuclear factor 4alpha coordinates a transcription factor network regulating hepatic fatty acid metabolism.

Martinez-Jimenez CP, Kyrmizi I, Cardot P, Gonzalez FJ, Talianidis I.

Mol Cell Biol. 2010 Feb;30(3):565-77. doi: 10.1128/MCB.00927-09. Epub 2009 Nov 23.

8.

Phytol directly activates peroxisome proliferator-activated receptor alpha (PPARalpha) and regulates gene expression involved in lipid metabolism in PPARalpha-expressing HepG2 hepatocytes.

Goto T, Takahashi N, Kato S, Egawa K, Ebisu S, Moriyama T, Fushiki T, Kawada T.

Biochem Biophys Res Commun. 2005 Nov 18;337(2):440-5. Epub 2005 Sep 21.

PMID:
16202384
9.

Peroxisome-proliferator-activated receptors as physiological sensors of fatty acid metabolism: molecular regulation in peroxisomes.

Latruffe N, Cherkaoui Malki M, Nicolas-Frances V, Jannin B, Clemencet MC, Hansmannel F, Passilly-Degrace P, Berlot JP.

Biochem Soc Trans. 2001 May;29(Pt 2):305-9.

PMID:
11356172
10.

Profiling of promoter occupancy by PPARalpha in human hepatoma cells via ChIP-chip analysis.

van der Meer DL, Degenhardt T, Väisänen S, de Groot PJ, Heinäniemi M, de Vries SC, Müller M, Carlberg C, Kersten S.

Nucleic Acids Res. 2010 May;38(9):2839-50. doi: 10.1093/nar/gkq012. Epub 2010 Jan 27.

11.

The role and regulation of the peroxisome proliferator activated receptor alpha in human liver.

Kersten S, Stienstra R.

Biochimie. 2017 May;136:75-84. doi: 10.1016/j.biochi.2016.12.019. Epub 2017 Jan 8. Review.

PMID:
28077274
12.

The ribosomal protein rpL11 associates with and inhibits the transcriptional activity of peroxisome proliferator-activated receptor-alpha.

Gray JP, Davis JW 2nd, Gopinathan L, Leas TL, Nugent CA, Vanden Heuvel JP.

Toxicol Sci. 2006 Feb;89(2):535-46. Epub 2005 Nov 9.

PMID:
16280383
13.

Transcriptomic signatures of peroxisome proliferator-activated receptor α (PPARα) in different mouse liver models identify novel aspects of its biology.

Szalowska E, Tesfay HA, van Hijum SA, Kersten S.

BMC Genomics. 2014 Dec 15;15:1106. doi: 10.1186/1471-2164-15-1106.

14.

Perfluorooctanoic acid (PFOA) affects distinct molecular signalling pathways in human primary hepatocytes.

Buhrke T, Krüger E, Pevny S, Rößler M, Bitter K, Lampen A.

Toxicology. 2015 Jul 3;333:53-62. doi: 10.1016/j.tox.2015.04.004. Epub 2015 Apr 11.

PMID:
25868421
15.

Hydrogen peroxide generation in peroxisome proliferator-induced oncogenesis.

Yeldandi AV, Rao MS, Reddy JK.

Mutat Res. 2000 Mar 17;448(2):159-77. Review.

PMID:
10725470
17.

MEK1 inhibits cardiac PPARα activity by direct interaction and prevents its nuclear localization.

el Azzouzi H, Leptidis S, Bourajjaj M, van Bilsen M, da Costa Martins PA, De Windt LJ.

PLoS One. 2012;7(6):e36799. doi: 10.1371/journal.pone.0036799. Epub 2012 Jun 19.

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Mouse OCTN2 is directly regulated by peroxisome proliferator-activated receptor alpha (PPARalpha) via a PPRE located in the first intron.

Wen G, Ringseis R, Eder K.

Biochem Pharmacol. 2010 Mar 1;79(5):768-76. doi: 10.1016/j.bcp.2009.10.002. Epub 2009 Oct 9.

PMID:
19819229
20.

Analysis of PPARalpha-dependent and PPARalpha-independent transcript regulation following fenofibrate treatment of human endothelial cells.

Araki H, Tamada Y, Imoto S, Dunmore B, Sanders D, Humphrey S, Nagasaki M, Doi A, Nakanishi Y, Yasuda K, Tomiyasu Y, Tashiro K, Print C, Charnock-Jones DS, Kuhara S, Miyano S.

Angiogenesis. 2009;12(3):221-9. doi: 10.1007/s10456-009-9142-8. Epub 2009 Apr 9.

PMID:
19357976

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