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Items: 1 to 20 of 154

1.

Involvement of cysteinyl leukotriene receptor 1 in Aβ1-42-induced neurotoxicity in vitro and in vivo.

Tang SS, Hong H, Chen L, Mei ZL, Ji MJ, Xiang GQ, Li N, Ji H.

Neurobiol Aging. 2014 Mar;35(3):590-9. doi: 10.1016/j.neurobiolaging.2013.09.036. Epub 2013 Oct 23.

PMID:
24269024
2.

Montelukast rescues primary neurons against Aβ1-42-induced toxicity through inhibiting CysLT1R-mediated NF-κB signaling.

Lai J, Mei ZL, Wang H, Hu M, Long Y, Miao MX, Li N, Hong H.

Neurochem Int. 2014 Sep;75:26-31. doi: 10.1016/j.neuint.2014.05.006. Epub 2014 May 28.

PMID:
24879954
3.

Montelukast targeting the cysteinyl leukotriene receptor 1 ameliorates Aβ1-42-induced memory impairment and neuroinflammatory and apoptotic responses in mice.

Lai J, Hu M, Wang H, Hu M, Long Y, Miao MX, Li JC, Wang XB, Kong LY, Hong H.

Neuropharmacology. 2014 Apr;79:707-14. doi: 10.1016/j.neuropharm.2014.01.011. Epub 2014 Jan 20.

PMID:
24456746
4.

Protective effect of pranlukast on Aβ₁₋₄₂-induced cognitive deficits associated with downregulation of cysteinyl leukotriene receptor 1.

Tang SS, Ji MJ, Chen L, Hu M, Long Y, Li YQ, Miao MX, Li JC, Li N, Ji H, Chen XJ, Hong H.

Int J Neuropsychopharmacol. 2014 Apr;17(4):581-92. doi: 10.1017/S1461145713001314. Epub 2013 Nov 11.

PMID:
24229499
5.

PPARδ agonist GW0742 ameliorates Aβ1-42-induced hippocampal neurotoxicity in mice.

An YQ, Zhang CT, Du Y, Zhang M, Tang SS, Hu M, Long Y, Sun HB, Hong H.

Metab Brain Dis. 2016 Jun;31(3):663-71. doi: 10.1007/s11011-016-9800-7. Epub 2016 Feb 11.

PMID:
26864581
6.

CysLT1R downregulation reverses intracerebroventricular streptozotocin-induced memory impairment via modulation of neuroinflammation in mice.

Ghosh A, Chen F, Wu F, Tang SS, Hu M, Long Y, Sun HB, Kong LY, Hong H.

Prog Neuropsychopharmacol Biol Psychiatry. 2017 Feb 6;73:19-30. doi: 10.1016/j.pnpbp.2016.10.001. Epub 2016 Oct 6.

PMID:
27720931
7.

Hippocampal CysLT1R knockdown or blockade represses LPS-induced depressive behaviors and neuroinflammatory response in mice.

Lin JR, Fang SC, Tang SS, Hu M, Long Y, Ghosh A, Sun HB, Kong LY, Hong H.

Acta Pharmacol Sin. 2017 Apr;38(4):477-487. doi: 10.1038/aps.2016.145. Epub 2017 Jan 23.

PMID:
28112182
8.

Montelukast ameliorates streptozotocin-induced cognitive impairment and neurotoxicity in mice.

Zhang CT, Lin JR, Wu F, Ghosh A, Tang SS, Hu M, Long Y, Sun HB, Hong H.

Neurotoxicology. 2016 Dec;57:214-222. doi: 10.1016/j.neuro.2016.09.022. Epub 2016 Oct 1.

PMID:
27702591
9.

Leukotriene D4 induces cognitive impairment through enhancement of CysLT₁ R-mediated amyloid-β generation in mice.

Tang SS, Wang XY, Hong H, Long Y, Li YQ, Xiang GQ, Jiang LY, Zhang HT, Liu LP, Miao MX, Hu M, Zhang TT, Hu W, Ji H, Ye FY.

Neuropharmacology. 2013 Feb;65:182-92. doi: 10.1016/j.neuropharm.2012.08.026. Epub 2012 Sep 12.

PMID:
22982445
10.

Chotosan improves Aβ1-42-induced cognitive impairment and neuroinflammatory and apoptotic responses through the inhibition of TLR-4/NF-κB signaling in mice.

Chen L, Hu L, Zhao J, Hong H, Feng F, Qu W, Liu W.

J Ethnopharmacol. 2016 Sep 15;191:398-407. doi: 10.1016/j.jep.2016.03.038. Epub 2016 Mar 16.

PMID:
26994819
11.

Risperidone ameliorated Aβ1-42-induced cognitive and hippocampal synaptic impairments in mice.

Wu L, Feng X, Li T, Sun B, Khan MZ, He L.

Behav Brain Res. 2017 Mar 30;322(Pt A):145-156. doi: 10.1016/j.bbr.2017.01.020. Epub 2017 Jan 16.

PMID:
28093254
12.

6-Shogaol has anti-amyloidogenic activity and ameliorates Alzheimer's disease via CysLT1R-mediated inhibition of cathepsin B.

Na JY, Song K, Lee JW, Kim S, Kwon J.

Biochem Biophys Res Commun. 2016 Aug 12;477(1):96-102. doi: 10.1016/j.bbrc.2016.06.026. Epub 2016 Jun 7.

PMID:
27286707
13.

Pretreatment with antiasthmatic drug ibudilast ameliorates Aβ 1-42-induced memory impairment and neurotoxicity in mice.

Wang H, Mei Zl, Zhong KL, Hu M, Long Y, Miao MX, Li N, Yan TH, Hong H.

Pharmacol Biochem Behav. 2014 Sep;124:373-9. doi: 10.1016/j.pbb.2014.07.006. Epub 2014 Jul 17.

PMID:
25038445
14.

DL0410, a novel dual cholinesterase inhibitor, protects mouse brains against Aβ-induced neuronal damage via the Akt/JNK signaling pathway.

Zhou D, Zhou W, Song JK, Feng ZY, Yang RY, Wu S, Wang L, Liu AL, Du GH.

Acta Pharmacol Sin. 2016 Nov;37(11):1401-1412. doi: 10.1038/aps.2016.87. Epub 2016 Aug 8.

15.

Leukotriene D4 induces amyloid-β generation via CysLT(1)R-mediated NF-κB pathways in primary neurons.

Wang XY, Tang SS, Hu M, Long Y, Li YQ, Liao MX, Ji H, Hong H.

Neurochem Int. 2013 Feb;62(3):340-7. doi: 10.1016/j.neuint.2013.01.002. Epub 2013 Jan 11.

PMID:
23318673
16.

Diammonium glycyrrhizinate upregulates PGC-1α and protects against Aβ1-42-induced neurotoxicity.

Zhu X, Chen C, Ye D, Guan D, Ye L, Jin J, Zhao H, Chen Y, Wang Z, Wang X, Xu Y.

PLoS One. 2012;7(4):e35823. doi: 10.1371/journal.pone.0035823. Epub 2012 Apr 23.

17.

Collaboration of geldanamycin-activated P70S6K and Hsp70 against beta-amyloid-induced hippocampal apoptosis: an approach to long-term memory and learning.

Zare N, Motamedi F, Digaleh H, Khodagholi F, Maghsoudi N.

Cell Stress Chaperones. 2015 Mar;20(2):309-19. doi: 10.1007/s12192-014-0550-3. Epub 2015 Jan 10.

18.

Intrahippocampal injection of Aβ1-42 inhibits neurogenesis and down-regulates IFN-γ and NF-κB expression in hippocampus of adult mouse brain.

Zheng M, Liu J, Ruan Z, Tian S, Ma Y, Zhu J, Li G.

Amyloid. 2013 Mar;20(1):13-20. doi: 10.3109/13506129.2012.755122. Epub 2013 Jan 4.

PMID:
23286786
19.

Preventive effect of genetic knockdown and pharmacological blockade of CysLT1R on lipopolysaccharide (LPS)-induced memory deficit and neurotoxicity in vivo.

Chen F, Ghosh A, Wu F, Tang S, Hu M, Sun H, Kong L, Hong H.

Brain Behav Immun. 2017 Feb;60:255-269. doi: 10.1016/j.bbi.2016.10.021. Epub 2016 Nov 1.

PMID:
27810377
20.

Knockdown of hippocampal cysteinyl leukotriene receptor 1 prevents depressive behavior and neuroinflammation induced by chronic mild stress in mice.

Yu XB, Dong RR, Wang H, Lin JR, An YQ, Du Y, Tang SS, Hu M, Long Y, Sun HB, Kong LY, Hong H.

Psychopharmacology (Berl). 2016 May;233(9):1739-49. doi: 10.1007/s00213-015-4136-2. Epub 2015 Nov 7.

PMID:
26546369

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