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Items: 1 to 20 of 432

1.

Flavonol isolated from ethanolic leaf extract of Thuja occidentalis arrests the cell cycle at G2-M and induces ROS-independent apoptosis in A549 cells, targeting nuclear DNA.

Mukherjee A, Sikdar S, Bishayee K, Boujedaini N, Khuda-Bukhsh AR.

Cell Prolif. 2014 Feb;47(1):56-71. doi: 10.1111/cpr.12079. Epub 2013 Nov 23.

PMID:
24267912
2.

Ethanolic extract of Thuja occidentalis blocks proliferation of A549 cells and induces apoptosis in vitro.

Mukherjee A, Sikdar S, Bishayee K, Paul A, Ghosh S, Boujedaini N, Khuda-Bukhsh AR.

Zhong Xi Yi Jie He Xue Bao. 2012 Dec;10(12):1451-9. doi: 10.3736/jcim20121218.

3.

Chamaejasmine induces apoptosis in human lung adenocarcinoma A549 cells through a Ros-mediated mitochondrial pathway.

Yu H, Zhang T, Cai L, Qu Y, Hu S, Dong G, Guan R, Xu X, Xing L.

Molecules. 2011 Sep 27;16(10):8165-80. doi: 10.3390/molecules16108165.

4.

Effects of 5,6-Dihydroxy-2,4-Dimethoxy-9,10-Dihydrophenanthrene on G2/M Cell Cycle Arrest and Apoptosis in Human Lung Carcinoma Cells.

Duangprompo W, Aree K, Itharat A, Hansakul P.

Am J Chin Med. 2016;44(7):1473-1490. Epub 2016 Oct 25.

PMID:
27776429
5.

Condurango glycoside-rich components stimulate DNA damage-induced cell cycle arrest and ROS-mediated caspase-3 dependent apoptosis through inhibition of cell-proliferation in lung cancer, in vitro and in vivo.

Sikdar S, Mukherjee A, Ghosh S, Khuda-Bukhsh AR.

Environ Toxicol Pharmacol. 2014 Jan;37(1):300-14. doi: 10.1016/j.etap.2013.12.004. Epub 2013 Dec 15.

PMID:
24384279
6.

PX-12 inhibits the growth of A549 lung cancer cells via G2/M phase arrest and ROS-dependent apoptosis.

You BR, Shin HR, Park WH.

Int J Oncol. 2014 Jan;44(1):301-8. doi: 10.3892/ijo.2013.2152. Epub 2013 Oct 29.

PMID:
24172913
7.

Reactive oxygen species-mediated mitochondrial pathway is involved in Baohuoside I-induced apoptosis in human non-small cell lung cancer.

Song J, Shu L, Zhang Z, Tan X, Sun E, Jin X, Chen Y, Jia X.

Chem Biol Interact. 2012 Jul 30;199(1):9-17. doi: 10.1016/j.cbi.2012.05.005. Epub 2012 Jun 9.

PMID:
22687635
8.

Antineoplastic effects of deoxyelephantopin, a sesquiterpene lactone from Elephantopus scaber, on lung adenocarcinoma (A549) cells.

Kabeer FA, Sreedevi GB, Nair MS, Rajalekshmi DS, Gopalakrishnan LP, Kunjuraman S, Prathapan R.

J Integr Med. 2013 Jul;11(4):269-77. doi: 10.3736/jintegrmed2013040.

PMID:
23867245
9.

Apoptosis induced by the methanol extract of Salvia miltiorrhiza Bunge in non-small cell lung cancer through PTEN-mediated inhibition of PI3K/Akt pathway.

Ye YT, Zhong W, Sun P, Wang D, Wang C, Hu LM, Qian JQ.

J Ethnopharmacol. 2017 Mar 22;200:107-116. doi: 10.1016/j.jep.2016.12.051. Epub 2017 Jan 12.

PMID:
28088493
10.

Ocimum sanctum induces apoptosis in A549 lung cancer cells and suppresses the in vivo growth of Lewis lung carcinoma cells.

Magesh V, Lee JC, Ahn KS, Lee HJ, Lee HJ, Lee EO, Shim BS, Jung HJ, Kim JS, Kim DK, Choi SH, Ahn KS, Kim SH.

Phytother Res. 2009 Oct;23(10):1385-91. doi: 10.1002/ptr.2784.

PMID:
19277950
11.

Grape proanthocyanidins induce apoptosis by loss of mitochondrial membrane potential of human non-small cell lung cancer cells in vitro and in vivo.

Singh T, Sharma SD, Katiyar SK.

PLoS One. 2011;6(11):e27444. doi: 10.1371/journal.pone.0027444. Epub 2011 Nov 8. Erratum in: PLoS One. 2012;7(6): doi/10.1371/annotation/23a8e553-4fce-4c73-9946-7a2a6a5729e9.

12.

Xanthatin induces cell cycle arrest at G2/M checkpoint and apoptosis via disrupting NF-κB pathway in A549 non-small-cell lung cancer cells.

Zhang L, Ruan J, Yan L, Li W, Wu Y, Tao L, Zhang F, Zheng S, Wang A, Lu Y.

Molecules. 2012 Mar 26;17(4):3736-50. doi: 10.3390/molecules17043736.

13.

Piper nigrum ethanolic extract rich in piperamides causes ROS overproduction, oxidative damage in DNA leading to cell cycle arrest and apoptosis in cancer cells.

de Souza Grinevicius VM, Kviecinski MR, Santos Mota NS, Ourique F, Porfirio Will Castro LS, Andreguetti RR, Gomes Correia JF, Filho DW, Pich CT, Pedrosa RC.

J Ethnopharmacol. 2016 Aug 2;189:139-47. doi: 10.1016/j.jep.2016.05.020. Epub 2016 May 10.

14.

The synthesized 2-(2-fluorophenyl)-6,7-methylenedioxyquinolin-4-one (CHM-1) promoted G2/M arrest through inhibition of CDK1 and induced apoptosis through the mitochondrial-dependent pathway in CT-26 murine colorectal adenocarcinoma cells.

Chou LC, Yang JS, Huang LJ, Wu HC, Lu CC, Chiang JH, Chen KT, Kuo SC, Chung JG.

J Gastroenterol. 2009;44(10):1055-63. doi: 10.1007/s00535-009-0111-1. Epub 2009 Aug 14.

PMID:
19688288
15.

Quercetin induces cytochrome-c release and ROS accumulation to promote apoptosis and arrest the cell cycle in G2/M, in cervical carcinoma: signal cascade and drug-DNA interaction.

Bishayee K, Ghosh S, Mukherjee A, Sadhukhan R, Mondal J, Khuda-Bukhsh AR.

Cell Prolif. 2013 Apr;46(2):153-63. doi: 10.1111/cpr.12017.

PMID:
23510470
16.

Antiproliferative effect of Toona sinensis leaf extract on non-small-cell lung cancer.

Yang CJ, Huang YJ, Wang CY, Wang PH, Hsu HK, Tsai MJ, Chen YC, Bharath Kumar V, Huang MS, Weng CF.

Transl Res. 2010 Jun;155(6):305-14. doi: 10.1016/j.trsl.2010.03.002. Epub 2010 Apr 13.

PMID:
20478545
18.

Ferruginol inhibits non-small cell lung cancer growth by inducing caspase-associated apoptosis.

Ho ST, Tung YT, Kuo YH, Lin CC, Wu JH.

Integr Cancer Ther. 2015 Jan;14(1):86-97. doi: 10.1177/1534735414555806. Epub 2014 Oct 28.

PMID:
25355727
19.

Anticancer activity of isoobtusilactone A from Cinnamomum kotoense: involvement of apoptosis, cell-cycle dysregulation, mitochondria regulation, and reactive oxygen species.

Chen CY, Chen CH, Lo YC, Wu BN, Wang HM, Lo WL, Yen CM, Lin RJ.

J Nat Prod. 2008 Jun;71(6):933-40. doi: 10.1021/np070620e. Epub 2008 May 20.

PMID:
18489163
20.

Corosolic acid induces apoptotic cell death in human lung adenocarcinoma A549 cells in vitro.

Nho KJ, Chun JM, Kim HK.

Food Chem Toxicol. 2013 Jun;56:8-17. doi: 10.1016/j.fct.2013.02.002. Epub 2013 Feb 20.

PMID:
23454206

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