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Items: 1 to 20 of 80

1.

Integrin CD11b negatively regulates BCR signalling to maintain autoreactive B cell tolerance.

Ding C, Ma Y, Chen X, Liu M, Cai Y, Hu X, Xiang D, Nath S, Zhang HG, Ye H, Powell D, Yan J.

Nat Commun. 2013;4:2813. doi: 10.1038/ncomms3813.

PMID:
24264377
2.

Tolerance through indifference: autoreactive B cells to the nuclear antigen La show no evidence of tolerance in a transgenic model.

Aplin BD, Keech CL, de Kauwe AL, Gordon TP, Cavill D, McCluskey J.

J Immunol. 2003 Dec 1;171(11):5890-900.

3.

CD22 is a negative regulator of B-cell receptor signalling.

Nitschke L, Carsetti R, Ocker B, Köhler G, Lamers MC.

Curr Biol. 1997 Feb 1;7(2):133-43.

4.

Developmental acquisition of the Lyn-CD22-SHP-1 inhibitory pathway promotes B cell tolerance.

Gross AJ, Lyandres JR, Panigrahi AK, Prak ET, DeFranco AL.

J Immunol. 2009 May 1;182(9):5382-92. doi: 10.4049/jimmunol.0803941.

5.

Polygenic autoimmune traits: Lyn, CD22, and SHP-1 are limiting elements of a biochemical pathway regulating BCR signaling and selection.

Cornall RJ, Cyster JG, Hibbs ML, Dunn AR, Otipoby KL, Clark EA, Goodnow CC.

Immunity. 1998 Apr;8(4):497-508.

7.

Receptor cross-talk spatially restricts p-ERK during TLR4 stimulation of autoreactive B cells.

Lee SR, Rutan JA, Monteith AJ, Jones SZ, Kang SA, Krum KN, Kilmon MA, Roques JR, Wagner NJ, Clarke SH, Vilen BJ.

J Immunol. 2012 Oct 15;189(8):3859-68. doi: 10.4049/jimmunol.1200940. Epub 2012 Sep 14.

8.

Expression of B cell receptor-associated signaling molecules in human lupus.

Huck S, Le Corre R, Youinou P, Zouali M.

Autoimmunity. 2001 May;33(3):213-24.

PMID:
11683380
9.

Analysis of Lyn/CD22 double-deficient B cells in vivo demonstrates Lyn- and CD22-independent pathways affecting BCR regulation and B cell survival.

Ferry H, Crockford TL, Silver K, Rust N, Goodnow CC, Cornall RJ.

Eur J Immunol. 2005 Dec;35(12):3655-63. Erratum in: Eur J Immunol. 2005 Dec;35(12):3714. Cockford, Tanya L [corrected to Crockford, Tanya L].

11.

CD22 x Siglec-G double-deficient mice have massively increased B1 cell numbers and develop systemic autoimmunity.

Jellusova J, Wellmann U, Amann K, Winkler TH, Nitschke L.

J Immunol. 2010 Apr 1;184(7):3618-27. doi: 10.4049/jimmunol.0902711. Epub 2010 Mar 3.

12.

IL-6 modulates CD5 expression in B cells from patients with lupus by regulating DNA methylation.

Garaud S, Le Dantec C, Jousse-Joulin S, Hanrotel-Saliou C, Saraux A, Mageed RA, Youinou P, Renaudineau Y.

J Immunol. 2009 May 1;182(9):5623-32. doi: 10.4049/jimmunol.0802412.

13.

Engagement of the B cell receptor for antigen differentially affects B cell responses to Toll-like receptor-7 agonists and antagonists in BXSB mice.

Layer T, Steele A, Goeken JA, Fleenor S, Lenert P.

Clin Exp Immunol. 2011 Mar;163(3):392-403. doi: 10.1111/j.1365-2249.2010.04307.x. Epub 2011 Jan 14.

14.

DNA-like class R inhibitory oligonucleotides (INH-ODNs) preferentially block autoantigen-induced B-cell and dendritic cell activation in vitro and autoantibody production in lupus-prone MRL-Fas(lpr/lpr) mice in vivo.

Lenert P, Yasuda K, Busconi L, Nelson P, Fleenor C, Ratnabalasuriar RS, Nagy PL, Ashman RF, Rifkin IR, Marshak-Rothstein A.

Arthritis Res Ther. 2009;11(3):R79. doi: 10.1186/ar2710. Epub 2009 May 28.

15.

Defective negative regulation of antigen receptor signaling in Lyn-deficient B lymphocytes.

Chan VW, Lowell CA, DeFranco AL.

Curr Biol. 1998 May 7;8(10):545-53.

16.

Tamoxifen blocks estrogen-induced B cell maturation but not survival.

Peeva E, Venkatesh J, Diamond B.

J Immunol. 2005 Aug 1;175(3):1415-23.

17.

L chain allelic inclusion does not increase autoreactivity in lupus-prone New Zealand Black/New Zealand White mice.

Makdasi E, Eilat D.

J Immunol. 2013 Feb 15;190(4):1472-80. doi: 10.4049/jimmunol.1202331. Epub 2013 Jan 14.

18.

Sustained activation of Lyn tyrosine kinase in vivo leads to autoimmunity.

Hibbs ML, Harder KW, Armes J, Kountouri N, Quilici C, Casagranda F, Dunn AR, Tarlinton DM.

J Exp Med. 2002 Dec 16;196(12):1593-604.

20.

Regulation of MHC class II signal transduction by the B cell coreceptors CD19 and CD22.

Bobbitt KR, Justement LB.

J Immunol. 2000 Nov 15;165(10):5588-96.

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