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Items: 1 to 20 of 193

1.

Metformin suppresses expression of the selenoprotein P gene via an AMP-activated kinase (AMPK)/FoxO3a pathway in H4IIEC3 hepatocytes.

Takayama H, Misu H, Iwama H, Chikamoto K, Saito Y, Murao K, Teraguchi A, Lan F, Kikuchi A, Saito R, Tajima N, Shirasaki T, Matsugo S, Miyamoto K, Kaneko S, Takamura T.

J Biol Chem. 2014 Jan 3;289(1):335-45. doi: 10.1074/jbc.M113.479386. Epub 2013 Nov 20.

2.

Eicosapentaenoic acid down-regulates expression of the selenoprotein P gene by inhibiting SREBP-1c protein independently of the AMP-activated protein kinase pathway in H4IIEC3 hepatocytes.

Tajima-Shirasaki N, Ishii KA, Takayama H, Shirasaki T, Iwama H, Chikamoto K, Saito Y, Iwasaki Y, Teraguchi A, Lan F, Kikuchi A, Takeshita Y, Murao K, Matsugo S, Kaneko S, Misu H, Takamura T.

J Biol Chem. 2017 Jun 30;292(26):10791-10800. doi: 10.1074/jbc.M116.747006. Epub 2017 May 2.

PMID:
28465347
3.

Metformin induces apoptosis and cell cycle arrest mediated by oxidative stress, AMPK and FOXO3a in MCF-7 breast cancer cells.

Queiroz EA, Puukila S, Eichler R, Sampaio SC, Forsyth HL, Lees SJ, Barbosa AM, Dekker RF, Fortes ZB, Khaper N.

PLoS One. 2014 May 23;9(5):e98207. doi: 10.1371/journal.pone.0098207. eCollection 2014.

4.

FoxO feedback control of basal IRS-2 expression in pancreatic β-cells is distinct from that in hepatocytes.

Tsunekawa S, Demozay D, Briaud I, McCuaig J, Accili D, Stein R, Rhodes CJ.

Diabetes. 2011 Nov;60(11):2883-91. doi: 10.2337/db11-0340. Epub 2011 Sep 20.

5.

Salsalate and Adiponectin Improve Palmitate-Induced Insulin Resistance via Inhibition of Selenoprotein P through the AMPK-FOXO1α Pathway.

Jung TW, Choi HY, Lee SY, Hong HC, Yang SJ, Yoo HJ, Youn BS, Baik SH, Choi KM.

PLoS One. 2013 Jun 18;8(6):e66529. doi: 10.1371/journal.pone.0066529. Print 2013.

6.

Metformin suppresses lipopolysaccharide (LPS)-induced inflammatory response in murine macrophages via activating transcription factor-3 (ATF-3) induction.

Kim J, Kwak HJ, Cha JY, Jeong YS, Rhee SD, Kim KR, Cheon HG.

J Biol Chem. 2014 Aug 15;289(33):23246-55. doi: 10.1074/jbc.M114.577908. Epub 2014 Jun 27.

7.

Metformin inhibits estrogen-dependent endometrial cancer cell growth by activating the AMPK-FOXO1 signal pathway.

Zou J, Hong L, Luo C, Li Z, Zhu Y, Huang T, Zhang Y, Yuan H, Hu Y, Wen T, Zhuang W, Cai B, Zhang X, Huang J, Cheng J.

Cancer Sci. 2016 Dec;107(12):1806-1817. doi: 10.1111/cas.13083. Epub 2016 Nov 25.

8.

Metformin enhances cisplatin cytotoxicity by suppressing signal transducer and activator of transcription-3 activity independently of the liver kinase B1-AMP-activated protein kinase pathway.

Lin CC, Yeh HH, Huang WL, Yan JJ, Lai WW, Su WP, Chen HH, Su WC.

Am J Respir Cell Mol Biol. 2013 Aug;49(2):241-50. doi: 10.1165/rcmb.2012-0244OC.

PMID:
23526220
9.

Involvement of oxygen-regulated protein 150 in AMP-activated protein kinase-mediated alleviation of lipid-induced endoplasmic reticulum stress.

Wang Y, Wu Z, Li D, Wang D, Wang X, Feng X, Xia M.

J Biol Chem. 2011 Apr 1;286(13):11119-31. doi: 10.1074/jbc.M110.203323. Epub 2011 Feb 4.

10.

Low concentrations of metformin suppress glucose production in hepatocytes through AMP-activated protein kinase (AMPK).

Cao J, Meng S, Chang E, Beckwith-Fickas K, Xiong L, Cole RN, Radovick S, Wondisford FE, He L.

J Biol Chem. 2014 Jul 25;289(30):20435-46.

11.

Selenoprotein P expression is controlled through interaction of the coactivator PGC-1alpha with FoxO1a and hepatocyte nuclear factor 4alpha transcription factors.

Speckmann B, Walter PL, Alili L, Reinehr R, Sies H, Klotz LO, Steinbrenner H.

Hepatology. 2008 Dec;48(6):1998-2006. doi: 10.1002/hep.22526.

PMID:
18972406
12.

AMPK activator-mediated inhibition of endoplasmic reticulum stress ameliorates carrageenan-induced insulin resistance through the suppression of selenoprotein P in HepG2 hepatocytes.

Jung TW, Lee SY, Hong HC, Choi HY, Yoo HJ, Baik SH, Choi KM.

Mol Cell Endocrinol. 2014 Jan 25;382(1):66-73. doi: 10.1016/j.mce.2013.09.013. Epub 2013 Sep 17.

PMID:
24055274
13.

AMP-activated protein kinase suppresses LXR-dependent sterol regulatory element-binding protein-1c transcription in rat hepatoma McA-RH7777 cells.

Yang J, Craddock L, Hong S, Liu ZM.

J Cell Biochem. 2009 Feb 15;106(3):414-26. doi: 10.1002/jcb.22024.

PMID:
19125418
14.

Regulation of Pancreatic β Cell Mass by Cross-Interaction between CCAAT Enhancer Binding Protein β Induced by Endoplasmic Reticulum Stress and AMP-Activated Protein Kinase Activity.

Matsuda T, Takahashi H, Mieda Y, Shimizu S, Kawamoto T, Matsuura Y, Takai T, Suzuki E, Kanno A, Koyanagi-Kimura M, Asahara S, Bartolome A, Yokoi N, Inoue H, Ogawa W, Seino S, Kido Y.

PLoS One. 2015 Jun 19;10(6):e0130757. doi: 10.1371/journal.pone.0130757. eCollection 2015.

15.

AMPK reverses the mesenchymal phenotype of cancer cells by targeting the Akt-MDM2-Foxo3a signaling axis.

Chou CC, Lee KH, Lai IL, Wang D, Mo X, Kulp SK, Shapiro CL, Chen CS.

Cancer Res. 2014 Sep 1;74(17):4783-95. doi: 10.1158/0008-5472.CAN-14-0135. Epub 2014 Jul 3.

16.

Selenoprotein P as a diabetes-associated hepatokine that impairs angiogenesis by inducing VEGF resistance in vascular endothelial cells.

Ishikura K, Misu H, Kumazaki M, Takayama H, Matsuzawa-Nagata N, Tajima N, Chikamoto K, Lan F, Ando H, Ota T, Sakurai M, Takeshita Y, Kato K, Fujimura A, Miyamoto K, Saito Y, Kameo S, Okamoto Y, Takuwa Y, Takahashi K, Kidoya H, Takakura N, Kaneko S, Takamura T.

Diabetologia. 2014 Sep;57(9):1968-76. doi: 10.1007/s00125-014-3306-9. Epub 2014 Jul 3.

PMID:
24989996
17.

Metformin inhibits hepatic gluconeogenesis through AMP-activated protein kinase-dependent regulation of the orphan nuclear receptor SHP.

Kim YD, Park KG, Lee YS, Park YY, Kim DK, Nedumaran B, Jang WG, Cho WJ, Ha J, Lee IK, Lee CH, Choi HS.

Diabetes. 2008 Feb;57(2):306-14. Epub 2007 Oct 1.

18.

Phosphorylation of serine 399 in LKB1 protein short form by protein kinase Cζ is required for its nucleocytoplasmic transport and consequent AMP-activated protein kinase (AMPK) activation.

Zhu H, Moriasi CM, Zhang M, Zhao Y, Zou MH.

J Biol Chem. 2013 Jun 7;288(23):16495-505. doi: 10.1074/jbc.M112.443580. Epub 2013 Apr 23.

19.
20.

Interference of selenium and selenoproteins with the insulin-regulated carbohydrate and lipid metabolism.

Steinbrenner H.

Free Radic Biol Med. 2013 Dec;65:1538-47. doi: 10.1016/j.freeradbiomed.2013.07.016. Epub 2013 Jul 18. Review.

PMID:
23872396

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