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Items: 1 to 20 of 257

2.

Engineering a high-affinity anti-IL-15 antibody: crystal structure reveals an α-helix in VH CDR3 as key component of paratope.

Lowe DC, Gerhardt S, Ward A, Hargreaves D, Anderson M, Ferraro F, Pauptit RA, Pattison DV, Buchanan C, Popovic B, Finch DK, Wilkinson T, Sleeman M, Vaughan TJ, Mallinder PR.

J Mol Biol. 2011 Feb 11;406(1):160-75. doi: 10.1016/j.jmb.2010.12.017. Epub 2010 Dec 16.

PMID:
21167836
3.

Building novel binding ligands to B7.1 and B7.2 based on human antibody single variable light chain domains.

van den Beucken T, van Neer N, Sablon E, Desmet J, Celis L, Hoogenboom HR, Hufton SE.

J Mol Biol. 2001 Jul 13;310(3):591-601.

PMID:
11439026
4.

Affinity maturation of a novel antagonistic human monoclonal antibody with a long VH CDR3 targeting the Class A GPCR formyl-peptide receptor 1.

Douthwaite JA, Sridharan S, Huntington C, Hammersley J, Marwood R, Hakulinen JK, Ek M, Sjögren T, Rider D, Privezentzev C, Seaman JC, Cariuk P, Knights V, Young J, Wilkinson T, Sleeman M, Finch DK, Lowe DC, Vaughan TJ.

MAbs. 2015;7(1):152-66. doi: 10.4161/19420862.2014.985158.

5.

The specificity properties that distinguish members of a set of homologous anti-digoxin antibodies are controlled by H chain mutations.

Near RI, Bruccoleri R, Novotny J, Hudson NW, White A, Mudgett-Hunter M.

J Immunol. 1991 Jan 15;146(2):627-33.

PMID:
1898959
6.

The critical role of arginine residues in the binding of human monoclonal antibodies to cardiolipin.

Giles I, Lambrianides N, Latchman D, Chen P, Chukwuocha R, Isenberg D, Rahman A.

Arthritis Res Ther. 2005;7(1):R47-56. Epub 2004 Nov 16.

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Fundamental characteristics of the expressed immunoglobulin VH and VL repertoire in different canine breeds in comparison with those of humans and mice.

Steiniger SC, Dunkle WE, Bammert GF, Wilson TL, Krishnan A, Dunham SA, Ippolito GC, Bainbridge G.

Mol Immunol. 2014 May;59(1):71-8. doi: 10.1016/j.molimm.2014.01.010. Epub 2014 Feb 4.

PMID:
24509215
10.

Construction of an scFv library by enzymatic assembly of V(L) and V(H) genes.

Kato M, Hanyu Y.

J Immunol Methods. 2013 Oct 31;396(1-2):15-22. doi: 10.1016/j.jim.2013.07.003. Epub 2013 Jul 31.

PMID:
23916870
11.

Improvement of anti-Burkholderia mouse monoclonal antibody from various phage-displayed single-chain antibody libraries.

Kim HS, Lo SC, Wear DJ, Stojadinovic A, Weina PJ, Izadjoo MJ.

J Immunol Methods. 2011 Sep 30;372(1-2):146-61. doi: 10.1016/j.jim.2011.07.009. Epub 2011 Jul 20.

PMID:
21787781
12.

Construction and molecular characterization of mouse single-chain variable fragment antibodies against Burkholderia mallei and Burkholderia pseudomallei.

Kim HS, Tsai S, Zou N, Lo SC, Wear DJ, Izadjoo MJ.

J Immunol Methods. 2011 Feb 28;365(1-2):101-9. doi: 10.1016/j.jim.2010.12.004. Epub 2010 Dec 21.

PMID:
21172353
13.

Ligation-based assembly for constructing mouse synthetic scFv libraries by chain shuffling with in vivo-amplified VH and VL fragments.

Nishi M, Jian N, Yamamoto K, Seto H, Nishida Y, Tonoyama Y, Shimizu N, Nishi Y.

J Immunol Methods. 2014 Oct;412:53-69. doi: 10.1016/j.jim.2014.06.016. Epub 2014 Jul 8.

PMID:
25010461
14.

Functional mapping of conserved residues located at the VL and VH domain interface of a Fab.

Chatellier J, Van Regenmortel MH, Vernet T, Altschuh D.

J Mol Biol. 1996 Nov 22;264(1):1-6.

PMID:
8950262
15.

Design and Generation of Humanized Single-chain Fv Derived from Mouse Hybridoma for Potential Targeting Application.

Khantasup K, Chantima W, Sangma C, Poomputsa K, Dharakul T.

Monoclon Antib Immunodiagn Immunother. 2015 Dec;34(6):404-17. doi: 10.1089/mab.2015.0036.

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Affinity maturation of a humanized rat antibody for anti-RAGE therapy: comprehensive mutagenesis reveals a high level of mutational plasticity both inside and outside the complementarity-determining regions.

Finlay WJ, Cunningham O, Lambert MA, Darmanin-Sheehan A, Liu X, Fennell BJ, Mahon CM, Cummins E, Wade JM, O'Sullivan CM, Tan XY, Piche N, Pittman DD, Paulsen J, Tchistiakova L, Kodangattil S, Gill D, Hufton SE.

J Mol Biol. 2009 May 8;388(3):541-58. doi: 10.1016/j.jmb.2009.03.019. Epub 2009 Mar 13.

PMID:
19285987
18.

Affinity maturation of phage display antibody populations using ribosome display.

Groves M, Lane S, Douthwaite J, Lowne D, Rees DG, Edwards B, Jackson RH.

J Immunol Methods. 2006 Jun 30;313(1-2):129-39. Epub 2006 May 11.

PMID:
16730741
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