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Items: 1 to 20 of 93

1.

Genetic amplification of PPME1 in gastric and lung cancer and its potential as a novel therapeutic target.

Li J, Han S, Qian Z, Su X, Fan S, Fu J, Liu Y, Yin X, Gao Z, Zhang J, Yu DH, Ji Q.

Cancer Biol Ther. 2014 Jan;15(1):128-34. doi: 10.4161/cbt.27146. Epub 2013 Nov 19.

2.

FGFR2 gene amplification in gastric cancer predicts sensitivity to the selective FGFR inhibitor AZD4547.

Xie L, Su X, Zhang L, Yin X, Tang L, Zhang X, Xu Y, Gao Z, Liu K, Zhou M, Gao B, Shen D, Zhang L, Ji J, Gavine PR, Zhang J, Kilgour E, Zhang X, Ji Q.

Clin Cancer Res. 2013 May 1;19(9):2572-83. doi: 10.1158/1078-0432.CCR-12-3898. Epub 2013 Mar 14.

3.

Protein phosphatase methylesterase-1 (PME-1) expression predicts a favorable clinical outcome in colorectal cancer.

Kaur A, Elzagheid A, Birkman EM, Avoranta T, Kytölä V, Korkeila E, Syrjänen K, Westermarck J, Sundström J.

Cancer Med. 2015 Dec;4(12):1798-808. doi: 10.1002/cam4.541. Epub 2015 Sep 17.

4.

IMP1 promotes choriocarcinoma cell migration and invasion through the novel effectors RSK2 and PPME1.

Hsieh YT, Chou MM, Chen HC, Tseng JJ.

Gynecol Oncol. 2013 Oct;131(1):182-90. doi: 10.1016/j.ygyno.2013.07.106. Epub 2013 Aug 1.

PMID:
23911878
5.

The CRKL gene encoding an adaptor protein is amplified, overexpressed, and a possible therapeutic target in gastric cancer.

Natsume H, Shinmura K, Tao H, Igarashi H, Suzuki M, Nagura K, Goto M, Yamada H, Maeda M, Konno H, Nakamura S, Sugimura H.

J Transl Med. 2012 Jul 3;10:97. doi: 10.1186/1479-5876-10-97.

6.

Frequent amplification of PTP1B is associated with poor survival of gastric cancer patients.

Wang N, She J, Liu W, Shi J, Yang Q, Shi B, Hou P.

Cell Cycle. 2015;14(5):732-43. doi: 10.1080/15384101.2014.998047.

7.

Integrative genomics identifies RAB23 as an invasion mediator gene in diffuse-type gastric cancer.

Hou Q, Wu YH, Grabsch H, Zhu Y, Leong SH, Ganesan K, Cross D, Tan LK, Tao J, Gopalakrishnan V, Tang BL, Kon OL, Tan P.

Cancer Res. 2008 Jun 15;68(12):4623-30. doi: 10.1158/0008-5472.CAN-07-5870.

8.

A novel method, digital genome scanning detects KRAS gene amplification in gastric cancers: involvement of overexpressed wild-type KRAS in downstream signaling and cancer cell growth.

Mita H, Toyota M, Aoki F, Akashi H, Maruyama R, Sasaki Y, Suzuki H, Idogawa M, Kashima L, Yanagihara K, Fujita M, Hosokawa M, Kusano M, Sabau SV, Tatsumi H, Imai K, Shinomura Y, Tokino T.

BMC Cancer. 2009 Jun 23;9:198. doi: 10.1186/1471-2407-9-198.

9.

TP53 genomic status regulates sensitivity of gastric cancer cells to the histone methylation inhibitor 3-deazaneplanocin A (DZNep).

Cheng LL, Itahana Y, Lei ZD, Chia NY, Wu Y, Yu Y, Zhang SL, Thike AA, Pandey A, Rozen S, Voorhoeve PM, Yu Q, Tan PH, Bay BH, Itahana K, Tan P.

Clin Cancer Res. 2012 Aug 1;18(15):4201-12. doi: 10.1158/1078-0432.CCR-12-0036. Epub 2012 Jun 6.

10.

Expression of livin in gastric cancer and induction of apoptosis in SGC-7901 cells by shRNA-mediated silencing of livin gene.

Wang TS, Ding QQ, Guo RH, Shen H, Sun J, Lu KH, You SH, Ge HM, Shu YQ, Liu P.

Biomed Pharmacother. 2010 May;64(5):333-8. doi: 10.1016/j.biopha.2009.06.002. Epub 2009 Oct 21.

PMID:
19914791
11.

MET amplification as a potential therapeutic target in gastric cancer.

Kawakami H, Okamoto I, Arao T, Okamoto W, Matsumoto K, Taniguchi H, Kuwata K, Yamaguchi H, Nishio K, Nakagawa K, Yamada Y.

Oncotarget. 2013 Jan;4(1):9-17.

12.

Krüppel-like factor 12 plays a significant role in poorly differentiated gastric cancer progression.

Nakamura Y, Migita T, Hosoda F, Okada N, Gotoh M, Arai Y, Fukushima M, Ohki M, Miyata S, Takeuchi K, Imoto I, Katai H, Yamaguchi T, Inazawa J, Hirohashi S, Ishikawa Y, Shibata T.

Int J Cancer. 2009 Oct 15;125(8):1859-67. doi: 10.1002/ijc.24538.

13.

Epigenetic inactivation of paired box gene 5, a novel tumor suppressor gene, through direct upregulation of p53 is associated with prognosis in gastric cancer patients.

Li X, Cheung KF, Ma X, Tian L, Zhao J, Go MY, Shen B, Cheng AS, Ying J, Tao Q, Sung JJ, Kung HF, Yu J.

Oncogene. 2012 Jul 19;31(29):3419-30. doi: 10.1038/onc.2011.511. Epub 2011 Nov 21. Erratum in: Oncogene. 2012 Jul 19;31(29):3482.

PMID:
22105368
14.

BTG1 expression correlates with pathogenesis, aggressive behaviors and prognosis of gastric cancer: a potential target for gene therapy.

Zheng HC, Li J, Shen DF, Yang XF, Zhao S, Wu YZ, Takano Y, Sun HZ, Su RJ, Luo JS, Gou WF.

Oncotarget. 2015 Aug 14;6(23):19685-705.

15.

Epidermal growth factor-like domain-containing protein 7 (EGFL7) enhances EGF receptor-AKT signaling, epithelial-mesenchymal transition, and metastasis of gastric cancer cells.

Luo BH, Xiong F, Wang JP, Li JH, Zhong M, Liu QL, Luo GQ, Yang XJ, Xiao N, Xie B, Xiao H, Liu RJ, Dong CS, Wang KS, Wen JF.

PLoS One. 2014 Jun 19;9(6):e99922. doi: 10.1371/journal.pone.0099922. eCollection 2014.

16.

Targeting cadherin-17 inactivates Ras/Raf/MEK/ERK signaling and inhibits cell proliferation in gastric cancer.

Lin Z, Zhang C, Zhang M, Xu D, Fang Y, Zhou Z, Chen X, Qin N, Zhang X.

PLoS One. 2014 Jan 20;9(1):e85296. doi: 10.1371/journal.pone.0085296. eCollection 2014.

17.

SMAD6 contributes to patient survival in non-small cell lung cancer and its knockdown reestablishes TGF-beta homeostasis in lung cancer cells.

Jeon HS, Dracheva T, Yang SH, Meerzaman D, Fukuoka J, Shakoori A, Shilo K, Travis WD, Jen J.

Cancer Res. 2008 Dec 1;68(23):9686-92. doi: 10.1158/0008-5472.CAN-08-1083.

18.

Fibroblast Growth Factor Receptor 1 and Related Ligands in Small-Cell Lung Cancer.

Zhang L, Yu H, Badzio A, Boyle TA, Schildhaus HU, Lu X, Dziadziuszko R, Jassem J, Varella-Garcia M, Heasley LE, Kowalewski AA, Ellison K, Chen G, Zhou C, Hirsch FR.

J Thorac Oncol. 2015 Jul;10(7):1083-90. doi: 10.1097/JTO.0000000000000562.

19.

Integrated genomic and functional analyses reveal glyoxalase I as a novel metabolic oncogene in human gastric cancer.

Hosoda F, Arai Y, Okada N, Shimizu H, Miyamoto M, Kitagawa N, Katai H, Taniguchi H, Yanagihara K, Imoto I, Inazawa J, Ohki M, Shibata T.

Oncogene. 2015 Feb 26;34(9):1196-206. doi: 10.1038/onc.2014.57. Epub 2014 Mar 24.

PMID:
24662817
20.

Long non-coding RNA metastasis-associated lung adenocarcinoma transcript 1 regulates the expression of Gli2 by miR-202 to strengthen gastric cancer progression.

Zhang Y, Chen Z, Li MJ, Guo HY, Jing NC.

Biomed Pharmacother. 2017 Jan;85:264-271. doi: 10.1016/j.biopha.2016.11.014. Epub 2016 Nov 22.

PMID:
27887846

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