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Items: 1 to 20 of 175

1.

Identification of a neuronal transcription factor network involved in medulloblastoma development.

Lastowska M, Al-Afghani H, Al-Balool HH, Sheth H, Mercer E, Coxhead JM, Redfern CP, Peters H, Burt AD, Santibanez-Koref M, Bacon CM, Chesler L, Rust AG, Adams DJ, Williamson D, Clifford SC, Jackson MS.

Acta Neuropathol Commun. 2013 Jul 11;1:35. doi: 10.1186/2051-5960-1-35.

2.

Serpine2/PN-1 Is Required for Proliferative Expansion of Pre-Neoplastic Lesions and Malignant Progression to Medulloblastoma.

Vaillant C, Valdivieso P, Nuciforo S, Kool M, Schwarzentruber-Schauerte A, Méreau H, Cabuy E, Lobrinus JA, Pfister S, Zuniga A, Frank S, Zeller R.

PLoS One. 2015 Apr 22;10(4):e0124870. doi: 10.1371/journal.pone.0124870. eCollection 2015.

3.

Developmental and oncogenic effects of insulin-like growth factor-I in Ptc1+/- mouse cerebellum.

Tanori M, Santone M, Mancuso M, Pasquali E, Leonardi S, Di Majo V, Rebessi S, Saran A, Pazzaglia S.

Mol Cancer. 2010 Mar 9;9:53. doi: 10.1186/1476-4598-9-53.

4.
5.

Genomic and transcriptomic analyses match medulloblastoma mouse models to their human counterparts.

Pöschl J, Stark S, Neumann P, Gröbner S, Kawauchi D, Jones DT, Northcott PA, Lichter P, Pfister SM, Kool M, Schüller U.

Acta Neuropathol. 2014 Jul;128(1):123-36. doi: 10.1007/s00401-014-1297-8. Epub 2014 May 29.

PMID:
24871706
6.

Dissecting the genomic complexity underlying medulloblastoma.

Jones DT, Jäger N, Kool M, Zichner T, Hutter B, Sultan M, Cho YJ, Pugh TJ, Hovestadt V, Stütz AM, Rausch T, Warnatz HJ, Ryzhova M, Bender S, Sturm D, Pleier S, Cin H, Pfaff E, Sieber L, Wittmann A, Remke M, Witt H, Hutter S, Tzaridis T, Weischenfeldt J, Raeder B, Avci M, Amstislavskiy V, Zapatka M, Weber UD, Wang Q, Lasitschka B, Bartholomae CC, Schmidt M, von Kalle C, Ast V, Lawerenz C, Eils J, Kabbe R, Benes V, van Sluis P, Koster J, Volckmann R, Shih D, Betts MJ, Russell RB, Coco S, Tonini GP, Schüller U, Hans V, Graf N, Kim YJ, Monoranu C, Roggendorf W, Unterberg A, Herold-Mende C, Milde T, Kulozik AE, von Deimling A, Witt O, Maass E, Rössler J, Ebinger M, Schuhmann MU, Frühwald MC, Hasselblatt M, Jabado N, Rutkowski S, von Bueren AO, Williamson D, Clifford SC, McCabe MG, Collins VP, Wolf S, Wiemann S, Lehrach H, Brors B, Scheurlen W, Felsberg J, Reifenberger G, Northcott PA, Taylor MD, Meyerson M, Pomeroy SL, Yaspo ML, Korbel JO, Korshunov A, Eils R, Pfister SM, Lichter P.

Nature. 2012 Aug 2;488(7409):100-5. doi: 10.1038/nature11284.

7.

Insulin-like growth factor 2 is required for progression to advanced medulloblastoma in patched1 heterozygous mice.

Corcoran RB, Bachar Raveh T, Barakat MT, Lee EY, Scott MP.

Cancer Res. 2008 Nov 1;68(21):8788-95. doi: 10.1158/0008-5472.CAN-08-2135.

8.

Sleeping Beauty mutagenesis in a mouse medulloblastoma model defines networks that discriminate between human molecular subgroups.

Genovesi LA, Ng CG, Davis MJ, Remke M, Taylor MD, Adams DJ, Rust AG, Ward JM, Ban KH, Jenkins NA, Copeland NG, Wainwright BJ.

Proc Natl Acad Sci U S A. 2013 Nov 12;110(46):E4325-34. doi: 10.1073/pnas.1318639110. Epub 2013 Oct 28.

9.
10.

Atoh1 inhibits neuronal differentiation and collaborates with Gli1 to generate medulloblastoma-initiating cells.

Ayrault O, Zhao H, Zindy F, Qu C, Sherr CJ, Roussel MF.

Cancer Res. 2010 Jul 1;70(13):5618-27. doi: 10.1158/0008-5472.CAN-09-3740. Epub 2010 Jun 1.

11.

Null mutation of DNA strand break-binding molecule poly(ADP-ribose) polymerase causes medulloblastomas in p53(-/-) mice.

Tong WM, Ohgaki H, Huang H, Granier C, Kleihues P, Wang ZQ.

Am J Pathol. 2003 Jan;162(1):343-52.

12.

Expression of Sonic hedgehog during cell proliferation in the human cerebellum.

Haldipur P, Bharti U, Govindan S, Sarkar C, Iyengar S, Gressens P, Mani S.

Stem Cells Dev. 2012 May 1;21(7):1059-68. doi: 10.1089/scd.2011.0206. Epub 2011 Aug 24.

PMID:
21732818
13.

Preponderance of sonic hedgehog pathway activation characterizes adult medulloblastoma.

Al-Halabi H, Nantel A, Klekner A, Guiot MC, Albrecht S, Hauser P, Garami M, Bognar L, Kavan P, Gerges N, Shirinian M, Roberge D, Muanza T, Jabado N.

Acta Neuropathol. 2011 Feb;121(2):229-39. doi: 10.1007/s00401-010-0780-0. Epub 2010 Nov 24.

PMID:
21107850
14.

Rapid diagnosis of medulloblastoma molecular subgroups.

Schwalbe EC, Lindsey JC, Straughton D, Hogg TL, Cole M, Megahed H, Ryan SL, Lusher ME, Taylor MD, Gilbertson RJ, Ellison DW, Bailey S, Clifford SC.

Clin Cancer Res. 2011 Apr 1;17(7):1883-94. doi: 10.1158/1078-0432.CCR-10-2210. Epub 2011 Feb 16.

15.

Patched1 deletion increases N-Myc protein stability as a mechanism of medulloblastoma initiation and progression.

Thomas WD, Chen J, Gao YR, Cheung B, Koach J, Sekyere E, Norris MD, Haber M, Ellis T, Wainwright B, Marshall GM.

Oncogene. 2009 Apr 2;28(13):1605-15. doi: 10.1038/onc.2009.3. Epub 2009 Feb 23.

PMID:
19234491
16.

Nos2 inactivation promotes the development of medulloblastoma in Ptch1(+/-) mice by deregulation of Gap43-dependent granule cell precursor migration.

Haag D, Zipper P, Westrich V, Karra D, Pfleger K, Toedt G, Blond F, Delhomme N, Hahn M, Reifenberger J, Reifenberger G, Lichter P.

PLoS Genet. 2012;8(3):e1002572. doi: 10.1371/journal.pgen.1002572. Epub 2012 Mar 15.

17.

Regulation of sonic hedgehog-GLI1 downstream target genes PTCH1, Cyclin D2, Plakoglobin, PAX6 and NKX2.2 and their epigenetic status in medulloblastoma and astrocytoma.

Shahi MH, Afzal M, Sinha S, Eberhart CG, Rey JA, Fan X, Castresana JS.

BMC Cancer. 2010 Nov 8;10:614. doi: 10.1186/1471-2407-10-614.

18.

Transcriptional up-regulation of Gadd45a in Patched-associated medulloblastoma.

Kappler R, Hess I, Schlegel J, Hahn H.

Int J Oncol. 2004 Jul;25(1):113-20.

PMID:
15201996
19.

Transcriptional profiling of the Sonic hedgehog response: a critical role for N-myc in proliferation of neuronal precursors.

Oliver TG, Grasfeder LL, Carroll AL, Kaiser C, Gillingham CL, Lin SM, Wickramasinghe R, Scott MP, Wechsler-Reya RJ.

Proc Natl Acad Sci U S A. 2003 Jun 10;100(12):7331-6. Epub 2003 May 30.

20.

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