Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 139

1.

Genome-wide regulatory analysis reveals that T-bet controls Th17 lineage differentiation through direct suppression of IRF4.

Gökmen MR, Dong R, Kanhere A, Powell N, Perucha E, Jackson I, Howard JK, Hernandez-Fuentes M, Jenner RG, Lord GM.

J Immunol. 2013 Dec 15;191(12):5925-32. doi: 10.4049/jimmunol.1202254. Epub 2013 Nov 18.

2.

T-bet and eomesodermin play critical roles in directing T cell differentiation to Th1 versus Th17.

Yang Y, Xu J, Niu Y, Bromberg JS, Ding Y.

J Immunol. 2008 Dec 15;181(12):8700-10.

3.

The transcription factor T-bet regulates mucosal T cell activation in experimental colitis and Crohn's disease.

Neurath MF, Weigmann B, Finotto S, Glickman J, Nieuwenhuis E, Iijima H, Mizoguchi A, Mizoguchi E, Mudter J, Galle PR, Bhan A, Autschbach F, Sullivan BM, Szabo SJ, Glimcher LH, Blumberg RS.

J Exp Med. 2002 May 6;195(9):1129-43. Erratum in: J Exp Med 2002 Jun 3;195(11):1513.

4.

T-bet over-expression regulates aryl hydrocarbon receptor-mediated T helper type 17 differentiation through an interferon (IFN)γ-independent pathway.

Yokosawa M, Kondo Y, Tahara M, Iizuka-Koga M, Segawa S, Kaneko S, Tsuboi H, Yoh K, Takahashi S, Matsumoto I, Sumida T.

Clin Exp Immunol. 2017 Apr;188(1):22-35. doi: 10.1111/cei.12912. Epub 2017 Jan 31.

PMID:
27936495
5.

Stat4 is critical for the balance between Th17 cells and regulatory T cells in colitis.

Xu J, Yang Y, Qiu G, Lal G, Yin N, Wu Z, Bromberg JS, Ding Y.

J Immunol. 2011 Jun 1;186(11):6597-606. doi: 10.4049/jimmunol.1004074. Epub 2011 Apr 27.

6.

T-bet inhibits the in vivo differentiation of parasite-specific CD4+ Th17 cells in a T cell-intrinsic manner.

Guo S, Cobb D, Smeltz RB.

J Immunol. 2009 May 15;182(10):6179-86. doi: 10.4049/jimmunol.0803821.

7.

NK cells inhibit T-bet-deficient, autoreactive Th17 cells.

Wu W, Shi S, Ljunggren HG, Cava AL, Van Kaer L, Shi FD, Liu R.

Scand J Immunol. 2012 Dec;76(6):559-66. doi: 10.1111/j.1365-3083.2012.02773.x.

8.

The transcription factor IFN regulatory factor-4 controls experimental colitis in mice via T cell-derived IL-6.

Mudter J, Amoussina L, Schenk M, Yu J, Brüstle A, Weigmann B, Atreya R, Wirtz S, Becker C, Hoffman A, Atreya I, Biesterfeld S, Galle PR, Lehr HA, Rose-John S, Mueller C, Lohoff M, Neurath MF.

J Clin Invest. 2008 Jul;118(7):2415-26. doi: 10.1172/JCI33227.

9.

T-bet is critical for the development of acute graft-versus-host disease through controlling T cell differentiation and function.

Fu J, Wang D, Yu Y, Heinrichs J, Wu Y, Schutt S, Kaosaard K, Liu C, Haarberg K, Bastian D, McDonald DG, Anasetti C, Yu XZ.

J Immunol. 2015 Jan 1;194(1):388-97. doi: 10.4049/jimmunol.1401618. Epub 2014 Nov 17.

10.

T-bet is essential for Th1-mediated, but not Th17-mediated, CNS autoimmune disease.

O'Connor RA, Cambrook H, Huettner K, Anderton SM.

Eur J Immunol. 2013 Nov;43(11):2818-23. doi: 10.1002/eji.201343689. Epub 2013 Aug 21.

11.

CD4 T cell-intrinsic IL-2 signaling differentially affects Th1 and Th17 development.

Fujimura K, Oyamada A, Iwamoto Y, Yoshikai Y, Yamada H.

J Leukoc Biol. 2013 Aug;94(2):271-9. doi: 10.1189/jlb.1112581. Epub 2013 May 28.

12.

STAT1-activating cytokines limit Th17 responses through both T-bet-dependent and -independent mechanisms.

Villarino AV, Gallo E, Abbas AK.

J Immunol. 2010 Dec 1;185(11):6461-71. doi: 10.4049/jimmunol.1001343. Epub 2010 Oct 25.

13.

Eomesodermin Expression in CD4+ T Cells Restricts Peripheral Foxp3 Induction.

Lupar E, Brack M, Garnier L, Laffont S, Rauch KS, Schachtrup K, Arnold SJ, Guéry JC, Izcue A.

J Immunol. 2015 Nov 15;195(10):4742-52. doi: 10.4049/jimmunol.1501159. Epub 2015 Oct 9.

14.

The transcription factors T-bet and Runx are required for the ontogeny of pathogenic interferon-γ-producing T helper 17 cells.

Wang Y, Godec J, Ben-Aissa K, Cui K, Zhao K, Pucsek AB, Lee YK, Weaver CT, Yagi R, Lazarevic V.

Immunity. 2014 Mar 20;40(3):355-66. doi: 10.1016/j.immuni.2014.01.002. Epub 2014 Feb 13.

15.

T-bet regulates the fate of Th1 and Th17 lymphocytes in autoimmunity.

Gocke AR, Cravens PD, Ben LH, Hussain RZ, Northrop SC, Racke MK, Lovett-Racke AE.

J Immunol. 2007 Feb 1;178(3):1341-8.

16.

T-bet-independent effects of IL-12 family cytokines on regulation of Th17 responses to experimental T. cruzi infection.

Cobb D, Hambright D, Smeltz RB.

J Leukoc Biol. 2010 Nov;88(5):965-71. doi: 10.1189/jlb.0410238. Epub 2010 Aug 31.

PMID:
20807701
17.
18.

Highly polarized Th17 cells induce EAE via a T-bet independent mechanism.

Grifka-Walk HM, Lalor SJ, Segal BM.

Eur J Immunol. 2013 Nov;43(11):2824-31. doi: 10.1002/eji.201343723. Epub 2013 Aug 23.

19.

T-bet protects against exacerbation of schistosome egg-induced immunopathology by regulating Th17-mediated inflammation.

Rutitzky LI, Smith PM, Stadecker MJ.

Eur J Immunol. 2009 Sep;39(9):2470-81. doi: 10.1002/eji.200939325.

20.

T-bet and GATA3 orchestrate Th1 and Th2 differentiation through lineage-specific targeting of distal regulatory elements.

Kanhere A, Hertweck A, Bhatia U, Gökmen MR, Perucha E, Jackson I, Lord GM, Jenner RG.

Nat Commun. 2012;3:1268. doi: 10.1038/ncomms2260.

Supplemental Content

Support Center