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Items: 1 to 20 of 368

1.

Protective effect of shikonin in experimental ischemic stroke: attenuated TLR4, p-p38MAPK, NF-κB, TNF-α and MMP-9 expression, up-regulated claudin-5 expression, ameliorated BBB permeability.

Wang L, Li Z, Zhang X, Wang S, Zhu C, Miao J, Chen L, Cui L, Qiao H.

Neurochem Res. 2014 Jan;39(1):97-106. doi: 10.1007/s11064-013-1194-x. Epub 2013 Nov 19.

PMID:
24248858
2.

Luteolin downregulates TLR4, TLR5, NF-κB and p-p38MAPK expression, upregulates the p-ERK expression, and protects rat brains against focal ischemia.

Qiao H, Zhang X, Zhu C, Dong L, Wang L, Zhang X, Xing Y, Wang C, Ji Y, Cao X.

Brain Res. 2012 Apr 11;1448:71-81. doi: 10.1016/j.brainres.2012.02.003. Epub 2012 Feb 9.

PMID:
22377454
3.

Parthenolide is neuroprotective in rat experimental stroke model: downregulating NF-κB, phospho-p38MAPK, and caspase-1 and ameliorating BBB permeability.

Dong L, Qiao H, Zhang X, Zhang X, Wang C, Wang L, Cui L, Zhao J, Xing Y, Li Y, Liu Z, Zhu C.

Mediators Inflamm. 2013;2013:370804. doi: 10.1155/2013/370804. Epub 2013 Jul 11.

4.

Neuroprotective effect of bicyclol in rat ischemic stroke: down-regulates TLR4, TLR9, TRAF6, NF-κB, MMP-9 and up-regulates claudin-5 expression.

Zhang J, Fu B, Zhang X, Chen L, Zhang L, Zhao X, Bai X, Zhu C, Cui L, Wang L.

Brain Res. 2013 Aug 28;1528:80-8. doi: 10.1016/j.brainres.2013.06.032. Epub 2013 Jul 10.

PMID:
23850770
5.

Tanshinone II A down-regulates HMGB1, RAGE, TLR4, NF-kappaB expression, ameliorates BBB permeability and endothelial cell function, and protects rat brains against focal ischemia.

Wang L, Zhang X, Liu L, Cui L, Yang R, Li M, Du W.

Brain Res. 2010 Mar 19;1321:143-51. doi: 10.1016/j.brainres.2009.12.046. Epub 2010 Jan 4.

PMID:
20043889
6.

Neuroprotection of early and short-time applying atorvastatin in the acute phase of cerebral ischemia: down-regulated 12/15-LOX, p38MAPK and cPLA2 expression, ameliorated BBB permeability.

Cui L, Zhang X, Yang R, Wang L, Liu L, Li M, Du W.

Brain Res. 2010 Apr 14;1325:164-73. doi: 10.1016/j.brainres.2010.02.036. Epub 2010 Feb 16.

PMID:
20167207
7.

Protective effect of naringenin in experimental ischemic stroke: down-regulated NOD2, RIP2, NF-κB, MMP-9 and up-regulated claudin-5 expression.

Bai X, Zhang X, Chen L, Zhang J, Zhang L, Zhao X, Zhao T, Zhao Y.

Neurochem Res. 2014 Aug;39(8):1405-15. doi: 10.1007/s11064-014-1326-y. Epub 2014 May 20.

PMID:
24842554
8.

Hydrogen sulfide protects blood-brain barrier integrity following cerebral ischemia.

Wang Y, Jia J, Ao G, Hu L, Liu H, Xiao Y, Du H, Alkayed NJ, Liu CF, Cheng J.

J Neurochem. 2014 Jun;129(5):827-38. doi: 10.1111/jnc.12695. Epub 2014 Mar 27.

9.

Ruscogenin reduces cerebral ischemic injury via NF-κB-mediated inflammatory pathway in the mouse model of experimental stroke.

Guan T, Liu Q, Qian Y, Yang H, Kong J, Kou J, Yu B.

Eur J Pharmacol. 2013 Aug 15;714(1-3):303-11. doi: 10.1016/j.ejphar.2013.07.036. Epub 2013 Jul 30.

PMID:
23911884
10.

Pretreatment by evodiamine is neuroprotective in cerebral ischemia: up-regulated pAkt, pGSK3β, down-regulated NF-κB expression, and ameliorated BBB permeability.

Zhao T, Zhang X, Zhao Y, Zhang L, Bai X, Zhang J, Zhao X, Chen L, Wang L, Cui L.

Neurochem Res. 2014 Aug;39(8):1612-20. doi: 10.1007/s11064-014-1356-5. Epub 2014 Jun 12.

PMID:
24919817
11.

Progesterone and allopregnanolone attenuate blood-brain barrier dysfunction following permanent focal ischemia by regulating the expression of matrix metalloproteinases.

Ishrat T, Sayeed I, Atif F, Hua F, Stein DG.

Exp Neurol. 2010 Nov;226(1):183-90. doi: 10.1016/j.expneurol.2010.08.023. Epub 2010 Sep 15.

12.

Green tea polyphenols alleviate early BBB damage during experimental focal cerebral ischemia through regulating tight junctions and PKCalpha signaling.

Liu X, Wang Z, Wang P, Yu B, Liu Y, Xue Y.

BMC Complement Altern Med. 2013 Jul 21;13:187. doi: 10.1186/1472-6882-13-187.

13.

Nobiletin protects against cerebral ischemia via activating the p-Akt, p-CREB, BDNF and Bcl-2 pathway and ameliorating BBB permeability in rat.

Zhang L, Zhao H, Zhang X, Chen L, Zhao X, Bai X, Zhang J.

Brain Res Bull. 2013 Jul;96:45-53. doi: 10.1016/j.brainresbull.2013.04.009. Epub 2013 May 2.

PMID:
23644141
14.

The protective role of Tongxinluo on blood-brain barrier after ischemia-reperfusion brain injury.

Liu Y, Tang GH, Sun YH, Lin XJ, Wei C, Yang GY, Liu JR.

J Ethnopharmacol. 2013 Jul 9;148(2):632-9. doi: 10.1016/j.jep.2013.05.018. Epub 2013 May 23.

PMID:
23707212
15.

2-Methoxystypandrone ameliorates brain function through preserving BBB integrity and promoting neurogenesis in mice with acute ischemic stroke.

Chern CM, Wang YH, Liou KT, Hou YC, Chen CC, Shen YC.

Biochem Pharmacol. 2014 Feb 1;87(3):502-14. doi: 10.1016/j.bcp.2013.11.018. Epub 2013 Dec 14.

PMID:
24342702
16.

The protective effect of HET0016 on brain edema and blood-brain barrier dysfunction after cerebral ischemia/reperfusion.

Liu Y, Wang D, Wang H, Qu Y, Xiao X, Zhu Y.

Brain Res. 2014 Jan 28;1544:45-53. doi: 10.1016/j.brainres.2013.11.031. Epub 2013 Dec 6.

PMID:
24316243
17.

Paeonol pretreatment attenuates cerebral ischemic injury via upregulating expression of pAkt, Nrf2, HO-1 and ameliorating BBB permeability in mice.

Zhao Y, Fu B, Zhang X, Zhao T, Chen L, Zhang J, Wang X.

Brain Res Bull. 2014 Oct;109:61-7. doi: 10.1016/j.brainresbull.2014.09.008. Epub 2014 Oct 5.

PMID:
25286445
18.

Toll-like receptor 4 is involved in brain damage and inflammation after experimental stroke.

Caso JR, Pradillo JM, Hurtado O, Lorenzo P, Moro MA, Lizasoain I.

Circulation. 2007 Mar 27;115(12):1599-608. Epub 2007 Mar 19.

19.

Ligustilide ameliorates neuroinflammation and brain injury in focal cerebral ischemia/reperfusion rats: involvement of inhibition of TLR4/peroxiredoxin 6 signaling.

Kuang X, Wang LF, Yu L, Li YJ, Wang YN, He Q, Chen C, Du JR.

Free Radic Biol Med. 2014 Jun;71:165-75. doi: 10.1016/j.freeradbiomed.2014.03.028. Epub 2014 Mar 26.

PMID:
24681253
20.

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