Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 56

1.

Design and synthesis of potent and selective P2X₃ receptor antagonists derived from PPADS as potential pain modulators.

Cho JH, Jung KY, Jung Y, Kim MH, Ko H, Park CS, Kim YC.

Eur J Med Chem. 2013;70:811-30. doi: 10.1016/j.ejmech.2013.10.026. Epub 2013 Oct 18.

PMID:
24246730
2.

Synthesis and structure-activity relationships of carboxylic acid derivatives of pyridoxal as P2X receptor antagonists.

Jung KY, Cho JH, Lee JS, Kim HJ, Kim YC.

Bioorg Med Chem. 2013 May 1;21(9):2643-50. doi: 10.1016/j.bmc.2013.01.073. Epub 2013 Feb 22.

PMID:
23510563
3.

Allosteric modulation and accelerated resensitization of human P2X(3) receptors by cibacron blue.

Alexander K, Niforatos W, Bianchi B, Burgard EC, Lynch KJ, Kowaluk EA, Jarvis MF, van Biesen T.

J Pharmacol Exp Ther. 1999 Dec;291(3):1135-42.

4.

Structure-activity relationships of pyridoxal phosphate derivatives as potent and selective antagonists of P2X1 receptors.

Kim YC, Brown SG, Harden TK, Boyer JL, Dubyak G, King BF, Burnstock G, Jacobson KA.

J Med Chem. 2001 Feb 1;44(3):340-9.

PMID:
11462975
5.

A pyridoxine cyclic phosphate and its 6-azoaryl derivative selectively potentiate and antagonize activation of P2X1 receptors.

Jacobson KA, Kim YC, Wildman SS, Mohanram A, Harden TK, Boyer JL, King BF, Burnstock G.

J Med Chem. 1998 Jun 18;41(13):2201-6.

PMID:
9632352
6.

TNP-ATP, a potent P2X3 receptor antagonist, blocks acetic acid-induced abdominal constriction in mice: comparison with reference analgesics.

Honore P, Mikusa J, Bianchi B, McDonald H, Cartmell J, Faltynek C, Jarvis MF.

Pain. 2002 Mar;96(1-2):99-105.

PMID:
11932066
7.

P2X1 and P2X3 receptors form stable trimers: a novel structural motif of ligand-gated ion channels.

Nicke A, Bäumert HG, Rettinger J, Eichele A, Lambrecht G, Mutschler E, Schmalzing G.

EMBO J. 1998 Jun 1;17(11):3016-28.

8.

Actions of a Series of PPADS Analogs at P2X1 and P2X3 Receptors.

Brown SG, Kim YC, Kim SA, Jacobson KA, Burnstock G, King BF.

Drug Dev Res. 2001 Aug;53(4):281-291. Epub 2001 Oct 18.

9.

Synthesis of pyridoxal phosphate derivatives with antagonist activity at the P2Y13 receptor.

Kim YC, Lee JS, Sak K, Marteau F, Mamedova L, Boeynaems JM, Jacobson KA.

Biochem Pharmacol. 2005 Jul 15;70(2):266-74.

10.

NF449, a novel picomolar potency antagonist at human P2X1 receptors.

Hülsmann M, Nickel P, Kassack M, Schmalzing G, Lambrecht G, Markwardt F.

Eur J Pharmacol. 2003 May 30;470(1-2):1-7.

PMID:
12787824
11.

Evaluation of adenine as scaffold for the development of novel P2X3 receptor antagonists.

Lambertucci C, Sundukova M, Kachare DD, Panmand DS, Dal Ben D, Buccioni M, Marucci G, Marchenkova A, Thomas A, Nistri A, Cristalli G, Volpini R.

Eur J Med Chem. 2013 Jul;65:41-50. doi: 10.1016/j.ejmech.2013.04.037. Epub 2013 Apr 24.

PMID:
23688699
13.

Opposite effects of zinc on human and rat P2X2 receptors.

Tittle RK, Hume RI.

J Neurosci. 2008 Oct 29;28(44):11131-40. doi: 10.1523/JNEUROSCI.2763-08.2008.

14.

Molecular and functional characterization of human P2X(2) receptors.

Lynch KJ, Touma E, Niforatos W, Kage KL, Burgard EC, van Biesen T, Kowaluk EA, Jarvis MF.

Mol Pharmacol. 1999 Dec;56(6):1171-81.

15.
16.

Evaluation of P2-purinoceptor antagonists at two relaxation-mediating P2-purinoceptors in guinea-pig taenia coli.

Bültmann R, Dudeck O, Starke K.

Naunyn Schmiedebergs Arch Pharmacol. 1996 Mar;353(4):445-51.

PMID:
8935712
17.

Agonists and antagonists acting at P2X receptors: selectivity profiles and functional implications.

Lambrecht G.

Naunyn Schmiedebergs Arch Pharmacol. 2000 Nov;362(4-5):340-50. Review.

PMID:
11111828
18.

Structure-activity relationship studies of spinorphin as a potent and selective human P2X(3) receptor antagonist.

Jung KY, Moon HD, Lee GE, Lim HH, Park CS, Kim YC.

J Med Chem. 2007 Sep 6;50(18):4543-7. Epub 2007 Aug 3.

PMID:
17676725
19.

Suppression of ATP-induced excitability in rat small-diameter trigeminal ganglion neurons by activation of GABAB receptor.

Takeda M, Ikeda M, Takahashi M, Kanazawa T, Nasu M, Matsumoto S.

Brain Res Bull. 2013 Sep;98:155-62. doi: 10.1016/j.brainresbull.2013.08.005. Epub 2013 Sep 1.

PMID:
24004472
20.

Role of extracellular histidines in antagonist sensitivity of the rat P2X4 receptor.

Xiong K, Stewart RR, Weight FF, Li C.

Neurosci Lett. 2004 Sep 2;367(2):197-200.

PMID:
15331152

Supplemental Content

Support Center