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Hearing loss in a mouse model of 22q11.2 Deletion Syndrome.

Fuchs JC, Zinnamon FA, Taylor RR, Ivins S, Scambler PJ, Forge A, Tucker AS, Linden JF.

PLoS One. 2013 Nov 14;8(11):e80104. doi: 10.1371/journal.pone.0080104. eCollection 2013.


Otitis media in a mouse model for Down syndrome.

Han F, Yu H, Zhang J, Tian C, Schmidt C, Nava C, Davisson MT, Zheng QY.

Int J Exp Pathol. 2009 Oct;90(5):480-8. doi: 10.1111/j.1365-2613.2009.00677.x.


Ectopic Mineralization and Conductive Hearing Loss in Enpp1asj Mutant Mice, a New Model for Otitis Media and Tympanosclerosis.

Tian C, Harris BS, Johnson KR.

PLoS One. 2016 Dec 13;11(12):e0168159. doi: 10.1371/journal.pone.0168159. eCollection 2016.


Ectopic mineralization in the middle ear and chronic otitis media with effusion caused by RPL38 deficiency in the Tail-short (Ts) mouse.

Noben-Trauth K, Latoche JR.

J Biol Chem. 2011 Jan 28;286(4):3079-93. doi: 10.1074/jbc.M110.184598. Epub 2010 Nov 9.


Thalamic miR-338-3p mediates auditory thalamocortical disruption and its late onset in models of 22q11.2 microdeletion.

Chun S, Du F, Westmoreland JJ, Han SB, Wang YD, Eddins D, Bayazitov IT, Devaraju P, Yu J, Mellado Lagarde MM, Anderson K, Zakharenko SS.

Nat Med. 2017 Jan;23(1):39-48. doi: 10.1038/nm.4240. Epub 2016 Nov 28.


Altered expression of hippocampal dentate granule neuron genes in a mouse model of human 22q11 deletion syndrome.

Jurata LW, Gallagher P, Lemire AL, Charles V, Brockman JA, Illingworth EL, Altar CA.

Schizophr Res. 2006 Dec;88(1-3):251-9. Epub 2006 Sep 26.


High frequency hearing loss associated with otitis media.

Hunter LL, Margolis RH, Rykken JR, Le CT, Daly KA, Giebink GS.

Ear Hear. 1996 Feb;17(1):1-11.


Association of Gel-Forming Mucins and Aquaporin Gene Expression With Hearing Loss, Effusion Viscosity, and Inflammation in Otitis Media With Effusion.

Samuels TL, Yan JC, Khampang P, Dettmar PW, MacKinnon A, Hong W, Johnston N, Papsin BC, Chun RH, McCormick ME, Kerschner JE.

JAMA Otolaryngol Head Neck Surg. 2017 Aug 1;143(8):810-817. doi: 10.1001/jamaoto.2017.0386.


A novel model of spontaneous otitis media with effusion (OME) in the Oxgr1 knock-out mouse.

Kerschner JE, Hong W, Taylor SR, Kerschner JA, Khampang P, Wrege KC, North PE.

Int J Pediatr Otorhinolaryngol. 2013 Jan;77(1):79-84. doi: 10.1016/j.ijporl.2012.09.037. Epub 2012 Nov 30.


Effect of middle ear fluid on sound transmission and auditory brainstem response in guinea pigs.

Guan X, Gan RZ.

Hear Res. 2011 Jul;277(1-2):96-106. doi: 10.1016/j.heares.2011.03.003. Epub 2011 Mar 21.


Tbx1 haploinsufficiency is linked to behavioral disorders in mice and humans: implications for 22q11 deletion syndrome.

Paylor R, Glaser B, Mupo A, Ataliotis P, Spencer C, Sobotka A, Sparks C, Choi CH, Oghalai J, Curran S, Murphy KC, Monks S, Williams N, O'Donovan MC, Owen MJ, Scambler PJ, Lindsay E.

Proc Natl Acad Sci U S A. 2006 May 16;103(20):7729-34. Epub 2006 May 9.


HIF-VEGF pathways are critical for chronic otitis media in Junbo and Jeff mouse mutants.

Cheeseman MT, Tyrer HE, Williams D, Hough TA, Pathak P, Romero MR, Hilton H, Bali S, Parker A, Vizor L, Purnell T, Vowell K, Wells S, Bhutta MF, Potter PK, Brown SD.

PLoS Genet. 2011 Oct;7(10):e1002336. doi: 10.1371/journal.pgen.1002336. Epub 2011 Oct 20.


Microarray analysis of the Df1 mouse model of the 22q11 deletion syndrome.

Prescott K, Ivins S, Hubank M, Lindsay E, Baldini A, Scambler P.

Hum Genet. 2005 May;116(6):486-96. Epub 2005 Mar 19.


Otitis media in the Tgif knockout mouse implicates TGFβ signalling in chronic middle ear inflammatory disease.

Tateossian H, Morse S, Parker A, Mburu P, Warr N, Acevedo-Arozena A, Cheeseman M, Wells S, Brown SD.

Hum Mol Genet. 2013 Jul 1;22(13):2553-65. doi: 10.1093/hmg/ddt103. Epub 2013 Mar 3.


Early otitis media with effusion, hearing loss, and auditory processes at school age.

Gravel JS, Roberts JE, Roush J, Grose J, Besing J, Burchinal M, Neebe E, Wallace IF, Zeisel S.

Ear Hear. 2006 Aug;27(4):353-68.


Selective overexpression of Comt in prefrontal cortex rescues schizophrenia-like phenotypes in a mouse model of 22q11 deletion syndrome.

Kimoto S, Muraki K, Toritsuka M, Mugikura S, Kajiwara K, Kishimoto T, Illingworth E, Tanigaki K.

Transl Psychiatry. 2012 Aug 7;2:e146. doi: 10.1038/tp.2012.70.


Mature middle and inner ears express Chd7 and exhibit distinctive pathologies in a mouse model of CHARGE syndrome.

Hurd EA, Adams ME, Layman WS, Swiderski DL, Beyer LA, Halsey KE, Benson JM, Gong TW, Dolan DF, Raphael Y, Martin DM.

Hear Res. 2011 Dec;282(1-2):184-95. doi: 10.1016/j.heares.2011.08.005. Epub 2011 Aug 23.


Quantitative experimental assessment of the factors contributing to hearing loss in serous otitis media.

Jeselsohn Y, Freeman S, Segal N, Sohmer H.

Otol Neurotol. 2005 Sep;26(5):1011-5.


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