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Items: 1 to 20 of 117

1.

P21-PARP-1 pathway is involved in cigarette smoke-induced lung DNA damage and cellular senescence.

Yao H, Sundar IK, Gorbunova V, Rahman I.

PLoS One. 2013 Nov 11;8(11):e80007. doi: 10.1371/journal.pone.0080007. eCollection 2013.

2.

PARP-1 and Ku compete for repair of DNA double strand breaks by distinct NHEJ pathways.

Wang M, Wu W, Wu W, Rosidi B, Zhang L, Wang H, Iliakis G.

Nucleic Acids Res. 2006;34(21):6170-82. Epub 2006 Nov 6.

3.

Ku70 and poly(ADP-ribose) polymerase-1 competitively regulate beta-catenin and T-cell factor-4-mediated gene transactivation: possible linkage of DNA damage recognition and Wnt signaling.

Idogawa M, Masutani M, Shitashige M, Honda K, Tokino T, Shinomura Y, Imai K, Hirohashi S, Yamada T.

Cancer Res. 2007 Feb 1;67(3):911-8.

4.

Down-regulation of PARP-1, but not of Ku80 or DNA-PKcs', results in higher gene targeting efficiency.

Domínguez-Bendala J, Masutani M, McWhir J.

Cell Biol Int. 2006 Apr;30(4):389-93. Epub 2006 Feb 28.

PMID:
16504547
5.

Hyperactivation of PARP triggers nonhomologous end-joining in repair-deficient mouse fibroblasts.

Gassman NR, Stefanick DF, Kedar PS, Horton JK, Wilson SH.

PLoS One. 2012;7(11):e49301. doi: 10.1371/journal.pone.0049301. Epub 2012 Nov 7.

6.
7.

Down-regulation of Ku autoantigen, DNA-dependent protein kinase, and poly(ADP-ribose) polymerase during cellular senescence.

Salminen A, Helenius M, Lahtinen T, Korhonen P, Tapiola T, Soininen H, Solovyan V.

Biochem Biophys Res Commun. 1997 Sep 29;238(3):712-6.

PMID:
9325154
8.

DNA damage response factors from diverse pathways, including DNA crosslink repair, mediate alternative end joining.

Howard SM, Yanez DA, Stark JM.

PLoS Genet. 2015 Jan 28;11(1):e1004943. doi: 10.1371/journal.pgen.1004943. eCollection 2015 Jan.

9.

Lethality in PARP-1/Ku80 double mutant mice reveals physiological synergy during early embryogenesis.

Henrie MS, Kurimasa A, Burma S, Ménissier-de Murcia J, de Murcia G, Li GC, Chen DJ.

DNA Repair (Amst). 2003 Feb 3;2(2):151-8.

PMID:
12531386
10.
11.

Ku counteracts mobilization of PARP1 and MRN in chromatin damaged with DNA double-strand breaks.

Cheng Q, Barboule N, Frit P, Gomez D, Bombarde O, Couderc B, Ren GS, Salles B, Calsou P.

Nucleic Acids Res. 2011 Dec;39(22):9605-19. doi: 10.1093/nar/gkr656. Epub 2011 Aug 31.

12.

Enhanced susceptibility of ovaries from obese mice to 7,12-dimethylbenz[a]anthracene-induced DNA damage.

Ganesan S, Nteeba J, Keating AF.

Toxicol Appl Pharmacol. 2014 Dec 1;281(2):203-10. doi: 10.1016/j.taap.2014.10.004. Epub 2014 Oct 22.

13.

Identification and biochemical characterization of a Werner's syndrome protein complex with Ku70/80 and poly(ADP-ribose) polymerase-1.

Li B, Navarro S, Kasahara N, Comai L.

J Biol Chem. 2004 Apr 2;279(14):13659-67. Epub 2004 Jan 20.

14.

Cellular senescence and organismal ageing in the absence of p21(CIP1/WAF1) in ku80(-/-) mice.

Zhao B, Benson EK, Qiao R, Wang X, Kim S, Manfredi JJ, Lee SW, Aaronson SA.

EMBO Rep. 2009 Jan;10(1):71-8. doi: 10.1038/embor.2008.220. Epub 2008 Dec 12. Erratum in: EMBO Rep. 2011 Mar;12(3):283.

15.

Topoisomerase IIβ associates with Ku70 and PARP-1 during double strand break repair of DNA in neurons.

Mandraju R, Chekuri A, Bhaskar C, Duning K, Kremerskothen J, Kondapi AK.

Arch Biochem Biophys. 2011 Dec 15;516(2):128-37. doi: 10.1016/j.abb.2011.09.017. Epub 2011 Oct 10.

PMID:
22019940
16.

Targeting of β1 integrins impairs DNA repair for radiosensitization of head and neck cancer cells.

Dickreuter E, Eke I, Krause M, Borgmann K, van Vugt MA, Cordes N.

Oncogene. 2016 Mar 17;35(11):1353-62. doi: 10.1038/onc.2015.212. Epub 2015 Jun 15.

PMID:
26073085
17.

Cigarette smoke-induced autophagy is regulated by SIRT1-PARP-1-dependent mechanism: implication in pathogenesis of COPD.

Hwang JW, Chung S, Sundar IK, Yao H, Arunachalam G, McBurney MW, Rahman I.

Arch Biochem Biophys. 2010 Aug 15;500(2):203-9. doi: 10.1016/j.abb.2010.05.013. Epub 2010 May 20.

18.

Poly(ADP-ribose) Polymerase 1 Interacts with Nuclear Respiratory Factor 1 (NRF-1) and Plays a Role in NRF-1 Transcriptional Regulation.

Hossain MB, Ji P, Anish R, Jacobson RH, Takada S.

J Biol Chem. 2009 Mar 27;284(13):8621-32. doi: 10.1074/jbc.M807198200. Epub 2009 Jan 30.

19.

PARP regulates nonhomologous end joining through retention of Ku at double-strand breaks.

Couto CA, Wang HY, Green JC, Kiely R, Siddaway R, Borer C, Pears CJ, Lakin ND.

J Cell Biol. 2011 Aug 8;194(3):367-75. doi: 10.1083/jcb.201012132. Epub 2011 Aug 1.

20.

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