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Items: 1 to 20 of 192

1.

AID and caspase 8 shape the germinal center response through apoptosis.

Boulianne B, Rojas OL, Haddad D, Zaheen A, Kapelnikov A, Nguyen T, Li C, Hakem R, Gommerman JL, Martin A.

J Immunol. 2013 Dec 15;191(12):5840-7. doi: 10.4049/jimmunol.1301776. Epub 2013 Nov 15.

2.

Apurinic/apyrimidinic endonuclease 2 regulates the expansion of germinal centers by protecting against activation-induced cytidine deaminase-independent DNA damage in B cells.

Guikema JE, Linehan EK, Esa N, Tsuchimoto D, Nakabeppu Y, Woodland RT, Schrader CE.

J Immunol. 2014 Jul 15;193(2):931-9. doi: 10.4049/jimmunol.1400002. Epub 2014 Jun 16.

3.

Accumulation of somatic hypermutation and antigen-driven selection in rapidly cycling surface Ig+ germinal center (GC) B cells which occupy GC at a high frequency during the primary anti-hapten response in mice.

Kimoto H, Nagaoka H, Adachi Y, Mizuochi T, Azuma T, Yagi T, Sata T, Yonehara S, Tsunetsugu-Yokota Y, Taniguchi M, Takemori T.

Eur J Immunol. 1997 Jan;27(1):268-79.

PMID:
9022029
4.

Activation-induced cytidine deaminase expression and activity in the absence of germinal centers: insights into hyper-IgM syndrome.

Kuraoka M, Liao D, Yang K, Allgood SD, Levesque MC, Kelsoe G, Ueda Y.

J Immunol. 2009 Sep 1;183(5):3237-48. doi: 10.4049/jimmunol.0901548. Epub 2009 Aug 10.

6.

Human germinal center B cells express the apoptosis-inducing genes Fas, c-myc, P53, and Bax but not the survival gene bcl-2.

Martinez-Valdez H, Guret C, de Bouteiller O, Fugier I, Banchereau J, Liu YJ.

J Exp Med. 1996 Mar 1;183(3):971-7.

7.

Inhibition of the catalytic function of activation-induced cytidine deaminase promotes apoptosis of germinal center B cells in BXD2 mice.

Hsu HC, Yang P, Wu Q, Wang JH, Job G, Guentert T, Li J, Stockard CR, Le TV, Chaplin DD, Grizzle WE, Mountz JD.

Arthritis Rheum. 2011 Jul;63(7):2038-48. doi: 10.1002/art.30257.

8.

Cutting edge: germinal centers formed in the absence of B cell-activating factor belonging to the TNF family exhibit impaired maturation and function.

Vora KA, Wang LC, Rao SP, Liu ZY, Majeau GR, Cutler AH, Hochman PS, Scott ML, Kalled SL.

J Immunol. 2003 Jul 15;171(2):547-51.

9.

Identification of murine germinal center B cell subsets defined by the expression of surface isotypes and differentiation antigens.

Shinall SM, Gonzalez-Fernandez M, Noelle RJ, Waldschmidt TJ.

J Immunol. 2000 Jun 1;164(11):5729-38.

10.

Somatic hypermutation in human B cell subsets.

Longo NS, Lipsky PE.

Springer Semin Immunopathol. 2001 Dec;23(4):367-85. Review. No abstract available.

PMID:
11826615
11.

AID-expressing germinal center B cells cluster normally within lymph node follicles in the absence of FDC-M1+ CD35+ follicular dendritic cells but dissipate prematurely.

Boulianne B, Le MX, Ward LA, Meng L, Haddad D, Li C, Martin A, Gommerman JL.

J Immunol. 2013 Nov 1;191(9):4521-30. doi: 10.4049/jimmunol.1300769. Epub 2013 Sep 25.

12.

AID constrains germinal center size by rendering B cells susceptible to apoptosis.

Zaheen A, Boulianne B, Parsa JY, Ramachandran S, Gommerman JL, Martin A.

Blood. 2009 Jul 16;114(3):547-54. doi: 10.1182/blood-2009-03-211763. Epub 2009 May 28.

13.

Human germinal center B cells differ from naive and memory B cells by their aggregated MHC class II-rich compartments lacking HLA-DO.

Chalouni C, Banchereau J, Vogt AB, Pascual V, Davoust J.

Int Immunol. 2003 Apr;15(4):457-66.

PMID:
12663675
14.

The RNase III enzyme Dicer is essential for germinal center B-cell formation.

Xu S, Guo K, Zeng Q, Huo J, Lam KP.

Blood. 2012 Jan 19;119(3):767-76. doi: 10.1182/blood-2011-05-355412. Epub 2011 Nov 23.

15.

Memory B cells without somatic hypermutation are generated from Bcl6-deficient B cells.

Toyama H, Okada S, Hatano M, Takahashi Y, Takeda N, Ichii H, Takemori T, Kuroda Y, Tokuhisa T.

Immunity. 2002 Sep;17(3):329-39.

16.

BH3-only protein Noxa regulates apoptosis in activated B cells and controls high-affinity antibody formation.

Wensveen FM, Derks IA, van Gisbergen KP, de Bruin AM, Meijers JC, Yigittop H, Nolte MA, Eldering E, van Lier RA.

Blood. 2012 Feb 9;119(6):1440-9. doi: 10.1182/blood-2011-09-378877. Epub 2011 Dec 5.

17.

High affinity IgM(+) memory B cells are generated through a germinal center-dependent pathway.

Hara Y, Tashiro Y, Murakami A, Nishimura M, Shimizu T, Kubo M, Burrows PD, Azuma T.

Mol Immunol. 2015 Dec;68(2 Pt C):617-27. doi: 10.1016/j.molimm.2015.10.003. Epub 2015 Oct 26.

PMID:
26514429
18.

Naive and memory B cells in T-cell-dependent and T-independent responses.

Zubler RH.

Springer Semin Immunopathol. 2001 Dec;23(4):405-19. Review.

PMID:
11826617
19.

Constitutive CD40L expression on B cells prematurely terminates germinal center response and leads to augmented plasma cell production in T cell areas.

Bolduc A, Long E, Stapler D, Cascalho M, Tsubata T, Koni PA, Shimoda M.

J Immunol. 2010 Jul 1;185(1):220-30. doi: 10.4049/jimmunol.0901689. Epub 2010 May 26. Erratum in: J Immunol. 2010 Aug 15;185(4):2631.

20.

Augmented antibody response with premature germinal center regression in CD40L transgenic mice.

Kishi Y, Aiba Y, Higuchi T, Furukawa K, Tokuhisa T, Takemori T, Tsubata T.

J Immunol. 2010 Jul 1;185(1):211-9. doi: 10.4049/jimmunol.0901694. Epub 2010 May 26.

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