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Genome-wide significant localization for working and spatial memory: Identifying genes for psychosis using models of cognition.

Knowles EE, Carless MA, de Almeida MA, Curran JE, McKay DR, Sprooten E, Dyer TD, Göring HH, Olvera R, Fox P, Almasy L, Duggirala R, Kent JW Jr, Blangero J, Glahn DC.

Am J Med Genet B Neuropsychiatr Genet. 2014 Jan;165B(1):84-95. doi: 10.1002/ajmg.b.32211. Epub 2013 Nov 14.


Variability in working memory performance explained by epistasis vs polygenic scores in the ZNF804A pathway.

Nicodemus KK, Hargreaves A, Morris D, Anney R, Gill M, Corvin A, Donohoe G; Schizophrenia Psychiatric Genome-wide Association Study (GWAS) Consortium; Wellcome Trust Case Control Consortium 2.

JAMA Psychiatry. 2014 Jul 1;71(7):778-85. doi: 10.1001/jamapsychiatry.2014.528.


High dimensional endophenotype ranking in the search for major depression risk genes.

Glahn DC, Curran JE, Winkler AM, Carless MA, Kent JW Jr, Charlesworth JC, Johnson MP, Göring HH, Cole SA, Dyer TD, Moses EK, Olvera RL, Kochunov P, Duggirala R, Fox PT, Almasy L, Blangero J.

Biol Psychiatry. 2012 Jan 1;71(1):6-14. doi: 10.1016/j.biopsych.2011.08.022. Epub 2011 Oct 7.


Discovering schizophrenia endophenotypes in randomly ascertained pedigrees.

Glahn DC, Williams JT, McKay DR, Knowles EE, Sprooten E, Mathias SR, Curran JE, Kent JW Jr, Carless MA, Göring HH, Dyer TD, Woolsey MD, Winkler AM, Olvera RL, Kochunov P, Fox PT, Duggirala R, Almasy L, Blangero J.

Biol Psychiatry. 2015 Jan 1;77(1):75-83. doi: 10.1016/j.biopsych.2014.06.027. Epub 2014 Jul 21.


Neurophysiologic effect of GWAS derived schizophrenia and bipolar risk variants.

Hall MH, Levy DL, Salisbury DF, Haddad S, Gallagher P, Lohan M, Cohen B, Ongür D, Smoller JW.

Am J Med Genet B Neuropsychiatr Genet. 2014 Jan;165B(1):9-18. doi: 10.1002/ajmg.b.32212. Epub 2013 Nov 8.


Common genetic variation and schizophrenia polygenic risk influence neurocognitive performance in young adulthood.

Hatzimanolis A, Bhatnagar P, Moes A, Wang R, Roussos P, Bitsios P, Stefanis CN, Pulver AE, Arking DE, Smyrnis N, Stefanis NC, Avramopoulos D.

Am J Med Genet B Neuropsychiatr Genet. 2015 Jul;168B(5):392-401. doi: 10.1002/ajmg.b.32323. Epub 2015 May 12.


The one and the many: effects of the cell adhesion molecule pathway on neuropsychological function in psychosis.

Hargreaves A, Anney R, O'Dushlaine C, Nicodemus KK; Schizophrenia Psychiatric Genome-Wide Association Study Consortium (PGC-SCZ); Wellcome Trust Case Control Consortium 2, Gill M, Corvin A, Morris D, Donohoe G.

Psychol Med. 2014 Jul;44(10):2177-87. doi: 10.1017/S0033291713002663. Epub 2013 Nov 28.


A schizophrenia gene locus on chromosome 17q21 in a new set of families of Mexican and central american ancestry: evidence from the NIMH Genetics of schizophrenia in latino populations study.

Escamilla M, Hare E, Dassori AM, Peralta JM, Ontiveros A, Nicolini H, Raventós H, Medina R, Mendoza R, Jerez A, Muñoz R, Almasy L.

Am J Psychiatry. 2009 Apr;166(4):442-9. doi: 10.1176/appi.ajp.2008.08040612. Epub 2009 Feb 2.


Psychosis susceptibility gene ZNF804A and cognitive performance in schizophrenia.

Walters JT, Corvin A, Owen MJ, Williams H, Dragovic M, Quinn EM, Judge R, Smith DJ, Norton N, Giegling I, Hartmann AM, Möller HJ, Muglia P, Moskvina V, Dwyer S, O'Donoghue T, Morar B, Cooper M, Chandler D, Jablensky A, Gill M, Kaladjieva L, Morris DW, O'Donovan MC, Rujescu D, Donohoe G.

Arch Gen Psychiatry. 2010 Jul;67(7):692-700. doi: 10.1001/archgenpsychiatry.2010.81.


Cognitive intermediate phenotype and genetic risk for psychosis.

Mark W, Toulopoulou T.

Curr Opin Neurobiol. 2016 Feb;36:23-30. doi: 10.1016/j.conb.2015.08.008. Epub 2015 Sep 9. Review.


Genetic variants on 3q21 and in the Sp8 transcription factor gene (SP8) as susceptibility loci for psychotic disorders: a genetic association study.

Kondo K, Ikeda M, Kajio Y, Saito T, Iwayama Y, Aleksic B, Yamada K, Toyota T, Hattori E, Ujike H, Inada T, Kunugi H, Kato T, Yoshikawa T, Ozaki N, Iwata N.

PLoS One. 2013 Aug 13;8(8):e70964. doi: 10.1371/journal.pone.0070964. eCollection 2013.


Influence of NOS1 on verbal intelligence and working memory in both patients with schizophrenia and healthy control subjects.

Donohoe G, Walters J, Morris DW, Quinn EM, Judge R, Norton N, Giegling I, Hartmann AM, Möller HJ, Muglia P, Williams H, Moskvina V, Peel R, O'Donoghue T, Owen MJ, O'Donovan MC, Gill M, Rujescu D, Corvin A.

Arch Gen Psychiatry. 2009 Oct;66(10):1045-54. doi: 10.1001/archgenpsychiatry.2009.139.


Effects of COMT genotype on cognitive ability and functional capacity in individuals with schizophrenia.

Twamley EW, Hua JP, Burton CZ, Vella L, Chinh K, Bilder RM, Kelsoe JR.

Schizophr Res. 2014 Oct;159(1):114-7. doi: 10.1016/j.schres.2014.07.041. Epub 2014 Aug 16.


Genome-wide significant linkage of schizophrenia-related neuroanatomical trait to 12q24.

Sprooten E, Gupta CN, Knowles EE, McKay DR, Mathias SR, Curran JE, Kent JW Jr, Carless MA, Almeida MA, Dyer TD, Göring HH, Olvera RL, Kochunov P, Fox PT, Duggirala R, Almasy L, Calhoun VD, Blangero J, Turner JA, Glahn DC.

Am J Med Genet B Neuropsychiatr Genet. 2015 Dec;168(8):678-86. doi: 10.1002/ajmg.b.32360. Epub 2015 Oct 5.


The role of the major histocompatibility complex region in cognition and brain structure: a schizophrenia GWAS follow-up.

Walters JT, Rujescu D, Franke B, Giegling I, Vásquez AA, Hargreaves A, Russo G, Morris DW, Hoogman M, Da Costa A, Moskvina V, Fernández G, Gill M, Corvin A, O'Donovan MC, Donohoe G, Owen MJ.

Am J Psychiatry. 2013 Aug;170(8):877-85. doi: 10.1176/appi.ajp.2013.12020226.


A promoter variant of SHANK1 affects auditory working memory in schizophrenia patients and in subjects clinically at risk for psychosis.

Lennertz L, Wagner M, Wölwer W, Schuhmacher A, Frommann I, Berning J, Schulze-Rauschenbach S, Landsberg MW, Steinbrecher A, Alexander M, Franke PE, Pukrop R, Ruhrmann S, Bechdolf A, Gaebel W, Klosterkötter J, Häfner H, Maier W, Mössner R.

Eur Arch Psychiatry Clin Neurosci. 2012 Mar;262(2):117-24. doi: 10.1007/s00406-011-0233-3. Epub 2011 Sep 7.


The CSMD1 genome-wide associated schizophrenia risk variant rs10503253 affects general cognitive ability and executive function in healthy males.

Koiliari E, Roussos P, Pasparakis E, Lencz T, Malhotra A, Siever LJ, Giakoumaki SG, Bitsios P.

Schizophr Res. 2014 Apr;154(1-3):42-7. doi: 10.1016/j.schres.2014.02.017. Epub 2014 Mar 11.


Neuropsychological profiles in different at-risk states of psychosis: executive control impairment in the early--and additional memory dysfunction in the late--prodromal state.

Frommann I, Pukrop R, Brinkmeyer J, Bechdolf A, Ruhrmann S, Berning J, Decker P, Riedel M, Möller HJ, Wölwer W, Gaebel W, Klosterkötter J, Maier W, Wagner M.

Schizophr Bull. 2011 Jul;37(4):861-73. doi: 10.1093/schbul/sbp155. Epub 2010 Jan 6.


Cognitive state and connectivity effects of the genome-wide significant psychosis variant in ZNF804A.

Esslinger C, Kirsch P, Haddad L, Mier D, Sauer C, Erk S, Schnell K, Arnold C, Witt SH, Rietschel M, Cichon S, Walter H, Meyer-Lindenberg A.

Neuroimage. 2011 Feb 1;54(3):2514-23. doi: 10.1016/j.neuroimage.2010.10.012. Epub 2010 Oct 12.


Cannabis and cognitive performance in psychosis: a cross-sectional study in patients with non-affective psychotic illness and their unaffected siblings.

Meijer JH, Dekker N, Koeter MW, Quee PJ, van Beveren NJ, Meijer CJ; Genetic Risk and Outcome of Psychosis (GROUP) Investigators.

Psychol Med. 2012 Apr;42(4):705-16. doi: 10.1017/S0033291711001656. Epub 2011 Sep 7.


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