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Items: 1 to 20 of 69

1.

Staging TDP-43 pathology in Alzheimer's disease.

Josephs KA, Murray ME, Whitwell JL, Parisi JE, Petrucelli L, Jack CR, Petersen RC, Dickson DW.

Acta Neuropathol. 2014 Mar;127(3):441-50. doi: 10.1007/s00401-013-1211-9. Epub 2013 Nov 16.

2.

Updated TDP-43 in Alzheimer's disease staging scheme.

Josephs KA, Murray ME, Whitwell JL, Tosakulwong N, Weigand SD, Petrucelli L, Liesinger AM, Petersen RC, Parisi JE, Dickson DW.

Acta Neuropathol. 2016 Apr;131(4):571-85. doi: 10.1007/s00401-016-1537-1. Epub 2016 Jan 25.

PMID:
26810071
3.

TAR DNA-binding protein 43 and pathological subtype of Alzheimer's disease impact clinical features.

Josephs KA, Whitwell JL, Tosakulwong N, Weigand SD, Murray ME, Liesinger AM, Petrucelli L, Senjem ML, Ivnik RJ, Parisi JE, Petersen RC, Dickson DW.

Ann Neurol. 2015 Nov;78(5):697-709. doi: 10.1002/ana.24493. Epub 2015 Sep 16.

4.

TDP-43 is a key player in the clinical features associated with Alzheimer's disease.

Josephs KA, Whitwell JL, Weigand SD, Murray ME, Tosakulwong N, Liesinger AM, Petrucelli L, Senjem ML, Knopman DS, Boeve BF, Ivnik RJ, Smith GE, Jack CR Jr, Parisi JE, Petersen RC, Dickson DW.

Acta Neuropathol. 2014;127(6):811-24. doi: 10.1007/s00401-014-1269-z. Epub 2014 Mar 23.

5.

TDP-43 stage, mixed pathologies, and clinical Alzheimer's-type dementia.

James BD, Wilson RS, Boyle PA, Trojanowski JQ, Bennett DA, Schneider JA.

Brain. 2016 Nov 1;139(11):2983-2993. doi: 10.1093/brain/aww224.

6.

Stages of granulovacuolar degeneration: their relation to Alzheimer's disease and chronic stress response.

Thal DR, Del Tredici K, Ludolph AC, Hoozemans JJ, Rozemuller AJ, Braak H, Knippschild U.

Acta Neuropathol. 2011 Nov;122(5):577-89. doi: 10.1007/s00401-011-0871-6. Epub 2011 Sep 21.

PMID:
21935637
7.

Temporal lobar predominance of TDP-43 neuronal cytoplasmic inclusions in Alzheimer disease.

Hu WT, Josephs KA, Knopman DS, Boeve BF, Dickson DW, Petersen RC, Parisi JE.

Acta Neuropathol. 2008 Aug;116(2):215-20. doi: 10.1007/s00401-008-0400-4. Epub 2008 Jul 1.

8.

Abnormal TDP-43 immunoreactivity in AD modifies clinicopathologic and radiologic phenotype.

Josephs KA, Whitwell JL, Knopman DS, Hu WT, Stroh DA, Baker M, Rademakers R, Boeve BF, Parisi JE, Smith GE, Ivnik RJ, Petersen RC, Jack CR Jr, Dickson DW.

Neurology. 2008 May 6;70(19 Pt 2):1850-7. doi: 10.1212/01.wnl.0000304041.09418.b1. Epub 2008 Apr 9.

9.

Abnormal TDP-43 expression is identified in the neocortex in cases of dementia pugilistica, but is mainly confined to the limbic system when identified in high and moderate stages of Alzheimer's disease.

King A, Sweeney F, Bodi I, Troakes C, Maekawa S, Al-Sarraj S.

Neuropathology. 2010 Aug;30(4):408-19. doi: 10.1111/j.1440-1789.2009.01085.x. Epub 2010 Jan 19.

PMID:
20102526
10.

Rates of hippocampal atrophy and presence of post-mortem TDP-43 in patients with Alzheimer's disease: a longitudinal retrospective study.

Josephs KA, Dickson DW, Tosakulwong N, Weigand SD, Murray ME, Petrucelli L, Liesinger AM, Senjem ML, Spychalla AJ, Knopman DS, Parisi JE, Petersen RC, Jack CR Jr, Whitwell JL.

Lancet Neurol. 2017 Nov;16(11):917-924. doi: 10.1016/S1474-4422(17)30284-3. Epub 2017 Sep 11.

PMID:
28919059
11.

TDP-43 in Alzheimer's disease is not associated with clinical FTLD or Parkinsonism.

Jung Y, Dickson DW, Murray ME, Whitwell JL, Knopman DS, Boeve BF, Jack CR Jr, Parisi JE, Petersen RC, Josephs KA.

J Neurol. 2014 Jul;261(7):1344-8. doi: 10.1007/s00415-014-7352-5. Epub 2014 Apr 24.

12.

TDP-43 pathological changes in early onset familial and sporadic Alzheimer's disease, late onset Alzheimer's disease and Down's syndrome: association with age, hippocampal sclerosis and clinical phenotype.

Davidson YS, Raby S, Foulds PG, Robinson A, Thompson JC, Sikkink S, Yusuf I, Amin H, DuPlessis D, Troakes C, Al-Sarraj S, Sloan C, Esiri MM, Prasher VP, Allsop D, Neary D, Pickering-Brown SM, Snowden JS, Mann DM.

Acta Neuropathol. 2011 Dec;122(6):703-13. doi: 10.1007/s00401-011-0879-y. Epub 2011 Oct 4.

PMID:
21968532
13.

Neuroimaging correlates of pathologically defined subtypes of Alzheimer's disease: a case-control study.

Whitwell JL, Dickson DW, Murray ME, Weigand SD, Tosakulwong N, Senjem ML, Knopman DS, Boeve BF, Parisi JE, Petersen RC, Jack CR Jr, Josephs KA.

Lancet Neurol. 2012 Oct;11(10):868-77. doi: 10.1016/S1474-4422(12)70200-4. Epub 2012 Sep 3.

14.

Concomitant TAR-DNA-binding protein 43 pathology is present in Alzheimer disease and corticobasal degeneration but not in other tauopathies.

Uryu K, Nakashima-Yasuda H, Forman MS, Kwong LK, Clark CM, Grossman M, Miller BL, Kretzschmar HA, Lee VM, Trojanowski JQ, Neumann M.

J Neuropathol Exp Neurol. 2008 Jun;67(6):555-64. doi: 10.1097/NEN.0b013e31817713b5.

15.

TAR DNA-binding protein 43 pathology in Alzheimer's disease with psychosis.

Vatsavayi AV, Kofler J, Demichele-Sweet MA, Murray PS, Lopez OL, Sweet RA.

Int Psychogeriatr. 2014 Jun;26(6):987-94. doi: 10.1017/S1041610214000246. Epub 2014 Mar 4.

16.

TDP-43 pathology and memory impairment in elders without pathologic diagnoses of AD or FTLD.

Nag S, Yu L, Wilson RS, Chen EY, Bennett DA, Schneider JA.

Neurology. 2017 Feb 14;88(7):653-660. doi: 10.1212/WNL.0000000000003610. Epub 2017 Jan 13.

17.

Cryptic exon incorporation occurs in Alzheimer's brain lacking TDP-43 inclusion but exhibiting nuclear clearance of TDP-43.

Sun M, Bell W, LaClair KD, Ling JP, Han H, Kageyama Y, Pletnikova O, Troncoso JC, Wong PC, Chen LL.

Acta Neuropathol. 2017 Jun;133(6):923-931. doi: 10.1007/s00401-017-1701-2. Epub 2017 Mar 22.

PMID:
28332094
18.

Concurrence of TDP-43, tau and alpha-synuclein pathology in brains of Alzheimer's disease and dementia with Lewy bodies.

Higashi S, Iseki E, Yamamoto R, Minegishi M, Hino H, Fujisawa K, Togo T, Katsuse O, Uchikado H, Furukawa Y, Kosaka K, Arai H.

Brain Res. 2007 Dec 12;1184:284-94. Epub 2007 Oct 25.

PMID:
17963732
20.

Imaging correlates of pathology in corticobasal syndrome.

Whitwell JL, Jack CR Jr, Boeve BF, Parisi JE, Ahlskog JE, Drubach DA, Senjem ML, Knopman DS, Petersen RC, Dickson DW, Josephs KA.

Neurology. 2010 Nov 23;75(21):1879-87. doi: 10.1212/WNL.0b013e3181feb2e8.

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