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Items: 1 to 20 of 221

1.

A novel Pex14 protein-interacting site of human Pex5 is critical for matrix protein import into peroxisomes.

Neuhaus A, Kooshapur H, Wolf J, Meyer NH, Madl T, Saidowsky J, Hambruch E, Lazam A, Jung M, Sattler M, Schliebs W, Erdmann R.

J Biol Chem. 2014 Jan 3;289(1):437-48. doi: 10.1074/jbc.M113.499707. Epub 2013 Nov 14.

2.

Structural basis for competitive interactions of Pex14 with the import receptors Pex5 and Pex19.

Neufeld C, Filipp FV, Simon B, Neuhaus A, Schüller N, David C, Kooshapur H, Madl T, Erdmann R, Schliebs W, Wilmanns M, Sattler M.

EMBO J. 2009 Mar 18;28(6):745-54. doi: 10.1038/emboj.2009.7. Epub 2009 Feb 5.

3.

PEX5 protein binds monomeric catalase blocking its tetramerization and releases it upon binding the N-terminal domain of PEX14.

Freitas MO, Francisco T, Rodrigues TA, Alencastre IS, Pinto MP, Grou CP, Carvalho AF, Fransen M, Sá-Miranda C, Azevedo JE.

J Biol Chem. 2011 Nov 25;286(47):40509-19. doi: 10.1074/jbc.M111.287201. Epub 2011 Oct 5.

4.

Identification of a novel, intraperoxisomal pex14-binding site in pex13: association of pex13 with the docking complex is essential for peroxisomal matrix protein import.

Schell-Steven A, Stein K, Amoros M, Landgraf C, Volkmer-Engert R, Rottensteiner H, Erdmann R.

Mol Cell Biol. 2005 Apr;25(8):3007-18.

5.

Analysis of the sequence motifs responsible for the interactions of peroxins 14 and 5, which are involved in glycosome biogenesis in Trypanosoma brucei.

Choe J, Moyersoen J, Roach C, Carter TL, Fan E, Michels PA, Hol WG.

Biochemistry. 2003 Sep 23;42(37):10915-22.

PMID:
12974625
7.

The di-aromatic pentapeptide repeats of the human peroxisome import receptor PEX5 are separate high affinity binding sites for the peroxisomal membrane protein PEX14.

Saidowsky J, Dodt G, Kirchberg K, Wegner A, Nastainczyk W, Kunau WH, Schliebs W.

J Biol Chem. 2001 Sep 14;276(37):34524-9. Epub 2001 Jul 3.

8.

Recombinant human peroxisomal targeting signal receptor PEX5. Structural basis for interaction of PEX5 with PEX14.

Schliebs W, Saidowsky J, Agianian B, Dodt G, Herberg FW, Kunau WH.

J Biol Chem. 1999 Feb 26;274(9):5666-73.

9.

PEX5, the shuttling import receptor for peroxisomal matrix proteins, is a redox-sensitive protein.

Apanasets O, Grou CP, Van Veldhoven PP, Brees C, Wang B, Nordgren M, Dodt G, Azevedo JE, Fransen M.

Traffic. 2014 Jan;15(1):94-103. doi: 10.1111/tra.12129. Epub 2013 Oct 31.

10.

Redox-regulated cargo binding and release by the peroxisomal targeting signal receptor, Pex5.

Ma C, Hagstrom D, Polley SG, Subramani S.

J Biol Chem. 2013 Sep 20;288(38):27220-31. doi: 10.1074/jbc.M113.492694. Epub 2013 Jul 31.

11.

Peroxisomal targeting signal-1 recognition by the TPR domains of human PEX5.

Gatto GJ Jr, Geisbrecht BV, Gould SJ, Berg JM.

Nat Struct Biol. 2000 Dec;7(12):1091-5. Erratum in: Nat Struct Biol 2002 Oct;9(10):788.

PMID:
11101887
12.

Ligand-induced compaction of the PEX5 receptor-binding cavity impacts protein import efficiency into peroxisomes.

Fodor K, Wolf J, Reglinski K, Passon DM, Lou Y, Schliebs W, Erdmann R, Wilmanns M.

Traffic. 2015 Jan;16(1):85-98. doi: 10.1111/tra.12238. Epub 2014 Dec 2.

13.

PEX14 binding to Arabidopsis PEX5 has differential effects on PTS1 and PTS2 cargo occupancy of the receptor.

Lanyon-Hogg T, Hooper J, Gunn S, Warriner SL, Baker A.

FEBS Lett. 2014 Jun 27;588(14):2223-9. doi: 10.1016/j.febslet.2014.05.038. Epub 2014 May 28.

15.
16.

A cargo-centered perspective on the PEX5 receptor-mediated peroxisomal protein import pathway.

Francisco T, Rodrigues TA, Freitas MO, Grou CP, Carvalho AF, Sá-Miranda C, Pinto MP, Azevedo JE.

J Biol Chem. 2013 Oct 4;288(40):29151-9. doi: 10.1074/jbc.M113.487140. Epub 2013 Aug 20.

17.

Covalent Label Transfer between Peroxisomal Importomer Components Reveals Export-driven Import Interactions.

Bhogal MS, Lanyon-Hogg T, Johnston KA, Warriner SL, Baker A.

J Biol Chem. 2016 Jan 29;291(5):2460-8. doi: 10.1074/jbc.M115.686501. Epub 2015 Nov 13.

18.

Distinct Pores for Peroxisomal Import of PTS1 and PTS2 Proteins.

Montilla-Martinez M, Beck S, Klümper J, Meinecke M, Schliebs W, Wagner R, Erdmann R.

Cell Rep. 2015 Dec 15;13(10):2126-34. doi: 10.1016/j.celrep.2015.11.016. Epub 2015 Dec 7.

19.

PEX12 interacts with PEX5 and PEX10 and acts downstream of receptor docking in peroxisomal matrix protein import.

Chang CC, Warren DS, Sacksteder KA, Gould SJ.

J Cell Biol. 1999 Nov 15;147(4):761-74.

20.

PEX14 is required for microtubule-based peroxisome motility in human cells.

Bharti P, Schliebs W, Schievelbusch T, Neuhaus A, David C, Kock K, Herrmann C, Meyer HE, Wiese S, Warscheid B, Theiss C, Erdmann R.

J Cell Sci. 2011 May 15;124(Pt 10):1759-68. doi: 10.1242/jcs.079368. Epub 2011 Apr 26.

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