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Items: 1 to 20 of 92

1.

Streptozotocin-induced diabetes increases amyloid plaque deposition in AD transgenic mice through modulating AGEs/RAGE/NF-κB pathway.

Wang X, Yu S, Hu JP, Wang CY, Wang Y, Liu HX, Liu YL.

Int J Neurosci. 2014 Aug;124(8):601-8. doi: 10.3109/00207454.2013.866110. Epub 2013 Dec 12.

PMID:
24228859
2.
3.

Trientine reduces BACE1 activity and mitigates amyloidosis via the AGE/RAGE/NF-κB pathway in a transgenic mouse model of Alzheimer's disease.

Wang CY, Xie JW, Xu Y, Wang T, Cai JH, Wang X, Zhao BL, An L, Wang ZY.

Antioxid Redox Signal. 2013 Dec 10;19(17):2024-39. doi: 10.1089/ars.2012.5158. Epub 2013 May 3.

4.

Resveratrol ameliorates vasculopathy in STZ-induced diabetic rats: role of AGE-RAGE signalling.

Jing YH, Chen KH, Yang SH, Kuo PC, Chen JK.

Diabetes Metab Res Rev. 2010 Mar;26(3):212-22. doi: 10.1002/dmrr.1076.

PMID:
20474069
5.

Advanced glycation endproducts and their receptor RAGE in Alzheimer's disease.

Srikanth V, Maczurek A, Phan T, Steele M, Westcott B, Juskiw D, Münch G.

Neurobiol Aging. 2011 May;32(5):763-77. doi: 10.1016/j.neurobiolaging.2009.04.016. Epub 2009 May 22. Review.

PMID:
19464758
6.

RAGE regulates BACE1 and Abeta generation via NFAT1 activation in Alzheimer's disease animal model.

Cho HJ, Son SM, Jin SM, Hong HS, Shin DH, Kim SJ, Huh K, Mook-Jung I.

FASEB J. 2009 Aug;23(8):2639-49. doi: 10.1096/fj.08-126383. Epub 2009 Mar 30.

PMID:
19332646
7.

PPARγ agonist pioglitazone reverses memory impairment and biochemical changes in a mouse model of type 2 diabetes mellitus.

Jiang LY, Tang SS, Wang XY, Liu LP, Long Y, Hu M, Liao MX, Ding QL, Hu W, Li JC, Hong H.

CNS Neurosci Ther. 2012 Aug;18(8):659-66. doi: 10.1111/j.1755-5949.2012.00341.x. Epub 2012 May 24.

PMID:
22620268
8.

Advanced glycation endproducts and pro-inflammatory cytokines in transgenic Tg2576 mice with amyloid plaque pathology.

Münch G, Apelt J, Rosemarie-Kientsch-Engel, Stahl P, Lüth HJ, Schliebs R.

J Neurochem. 2003 Jul;86(2):283-9.

9.

AGEs/RAGE complex upregulates BACE1 via NF-κB pathway activation.

Guglielmotto M, Aragno M, Tamagno E, Vercellinatto I, Visentin S, Medana C, Catalano MG, Smith MA, Perry G, Danni O, Boccuzzi G, Tabaton M.

Neurobiol Aging. 2012 Jan;33(1):196.e13-27. doi: 10.1016/j.neurobiolaging.2010.05.026. Epub 2010 Jul 17.

PMID:
20638753
10.

Possible involvement of advanced glycation end-products (AGEs) in the pathogenesis of Alzheimer's disease.

Takeuchi M, Yamagishi S.

Curr Pharm Des. 2008;14(10):973-8. Review.

PMID:
18473848
11.

Qifu-Yin attenuates AGEs-induced Alzheimer-like pathophysiological changes through the RAGE/NF-κB pathway.

Wang SY, Liu JP, Ji WW, Chen WJ, Fu Q, Feng L, Ma SP.

Chin J Nat Med. 2014 Dec;12(12):920-8. doi: 10.1016/S1875-5364(14)60135-7.

PMID:
25556063
12.

Diabetes-associated sustained activation of the transcription factor nuclear factor-kappaB.

Bierhaus A, Schiekofer S, Schwaninger M, Andrassy M, Humpert PM, Chen J, Hong M, Luther T, Henle T, Klöting I, Morcos M, Hofmann M, Tritschler H, Weigle B, Kasper M, Smith M, Perry G, Schmidt AM, Stern DM, Häring HU, Schleicher E, Nawroth PP.

Diabetes. 2001 Dec;50(12):2792-808.

13.

Preventing activation of receptor for advanced glycation endproducts in Alzheimer's disease.

Lue LF, Yan SD, Stern DM, Walker DG.

Curr Drug Targets CNS Neurol Disord. 2005 Jun;4(3):249-66. Review.

PMID:
15975028
14.
15.

RAGE mediates accelerated diabetic vein graft atherosclerosis induced by combined mechanical stress and AGEs via synergistic ERK activation.

Li Y, Liu S, Zhang Z, Xu Q, Xie F, Wang J, Ping S, Li C, Wang Z, Zhang M, Huang J, Chen D, Hu L, Li C.

PLoS One. 2012;7(4):e35016. doi: 10.1371/journal.pone.0035016. Epub 2012 Apr 9.

16.

Immunohistochemical analysis of human brain suggests pathological synergism of Alzheimer's disease and diabetes mellitus.

Valente T, Gella A, Fernàndez-Busquets X, Unzeta M, Durany N.

Neurobiol Dis. 2010 Jan;37(1):67-76. doi: 10.1016/j.nbd.2009.09.008. Epub 2009 Sep 22.

PMID:
19778613
17.

Attenuation of aortic injury by ursolic acid through RAGE-Nox-NFκB pathway in streptozocin-induced diabetic rats.

Xiang M, Wang J, Zhang Y, Ling J, Xu X.

Arch Pharm Res. 2012 May;35(5):877-86. doi: 10.1007/s12272-012-0513-0. Epub 2012 May 29.

PMID:
22644855
18.
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20.

RAGE modulates vascular inflammation and atherosclerosis in a murine model of type 2 diabetes.

Wendt T, Harja E, Bucciarelli L, Qu W, Lu Y, Rong LL, Jenkins DG, Stein G, Schmidt AM, Yan SF.

Atherosclerosis. 2006 Mar;185(1):70-7. Epub 2005 Aug 1.

PMID:
16076470

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