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Items: 1 to 20 of 118

1.

Increased sequence coverage through combined targeting of variant and conserved epitopes correlates with control of HIV replication.

Sunshine J, Kim M, Carlson JM, Heckerman D, Czartoski J, Migueles SA, Maenza J, McElrath MJ, Mullins JI, Frahm N.

J Virol. 2014 Jan;88(2):1354-65. doi: 10.1128/JVI.02361-13. Epub 2013 Nov 13.

2.

Fitness-Balanced Escape Determines Resolution of Dynamic Founder Virus Escape Processes in HIV-1 Infection.

Sunshine JE, Larsen BB, Maust B, Casey E, Deng W, Chen L, Westfall DH, Kim M, Zhao H, Ghorai S, Lanxon-Cookson E, Rolland M, Collier AC, Maenza J, Mullins JI, Frahm N.

J Virol. 2015 Oct;89(20):10303-18. doi: 10.1128/JVI.01876-15. Epub 2015 Jul 29.

3.

Targeting of conserved gag-epitopes in early HIV infection is associated with lower plasma viral load and slower CD4(+) T cell depletion.

Perez CL, Milush JM, Buggert M, Eriksson EM, Larsen MV, Liegler T, Hartogensis W, Bacchetti P, Lund O, Hecht FM, Nixon DF, Karlsson AC.

AIDS Res Hum Retroviruses. 2013 Mar;29(3):602-12. doi: 10.1089/AID.2012.0171. Epub 2013 Jan 8.

4.

Clinical Control of HIV-1 by Cytotoxic T Cells Specific for Multiple Conserved Epitopes.

Murakoshi H, Akahoshi T, Koyanagi M, Chikata T, Naruto T, Maruyama R, Tamura Y, Ishizuka N, Gatanaga H, Oka S, Takiguchi M.

J Virol. 2015 May;89(10):5330-9. doi: 10.1128/JVI.00020-15. Epub 2015 Mar 4.

5.

CD4 responses to conserved HIV-1 T helper epitopes show both negative and positive associations with virus load in chronically infected subjects.

Boaz MJ, Waters A, Murad S, Easterbrook PJ, D'Sousa E, van Wheeley C, Vyakarnam A.

Clin Exp Immunol. 2003 Dec;134(3):454-63.

6.

Differential escape patterns within the dominant HLA-B*57:03-restricted HIV Gag epitope reflect distinct clade-specific functional constraints.

Payne RP, Branch S, Kløverpris H, Matthews PC, Koofhethile CK, Strong T, Adland E, Leitman E, Frater J, Ndung'u T, Hunter E, Haubrich R, Mothe B, Edwards A, Riddell L, Chen F, Harrigan PR, Brumme ZL, Mallal S, John M, Jooste JP, Shapiro R, Deeks SG, Walker BD, Brander C, Landis C, Carlson JM, Prado JG, Goulder PJ.

J Virol. 2014 May;88(9):4668-78. doi: 10.1128/JVI.03303-13. Epub 2014 Feb 5.

7.

Deficiency of HIV-Gag-specific T cells in early childhood correlates with poor viral containment.

Huang S, Dunkley-Thompson J, Tang Y, Macklin EA, Steel-Duncan J, Singh-Minott I, Ryland EG, Smikle M, Walker BD, Christie CD, Feeney ME.

J Immunol. 2008 Dec 1;181(11):8103-11.

8.

Viral replication capacity as a correlate of HLA B57/B5801-associated nonprogressive HIV-1 infection.

Navis M, Schellens I, van Baarle D, Borghans J, van Swieten P, Miedema F, Kootstra N, Schuitemaker H.

J Immunol. 2007 Sep 1;179(5):3133-43.

9.

Intra- and inter-clade cross-reactivity by HIV-1 Gag specific T-cells reveals exclusive and commonly targeted regions: implications for current vaccine trials.

Zembe L, Burgers WA, Jaspan HB, Bekker LG, Bredell H, Stevens G, Gilmour J, Cox JH, Fast P, Hayes P, Vardas E, Williamson C, Gray CM.

PLoS One. 2011;6(10):e26096. doi: 10.1371/journal.pone.0026096. Epub 2011 Oct 12.

10.

Multi-layered Gag-specific immunodominant responses contribute to improved viral control in the CRF01_AE subtype of HIV-1-infected MSM subjects.

Jiang F, Han X, Zhang H, Zhao B, An M, Xu J, Chu Z, Dong T, Shang H.

BMC Immunol. 2016 Aug 30;17(1):28. doi: 10.1186/s12865-016-0166-8.

11.

Profile of T cell recognition of HIV type 1 consensus group M Gag and Nef peptides in a clade A1- and D-infected Ugandan population.

Serwanga J, Mugaba S, Pimego E, Nanteza B, Lyagoba F, Nakubulwa S, Heath L, Nsubuga RN, Ndembi N, Gotch F, Kaleebu P.

AIDS Res Hum Retroviruses. 2012 Apr;28(4):384-92. doi: 10.1089/AID.2011.0175. Epub 2011 Oct 17.

12.

Gag-protease-mediated replication capacity in HIV-1 subtype C chronic infection: associations with HLA type and clinical parameters.

Wright JK, Brumme ZL, Carlson JM, Heckerman D, Kadie CM, Brumme CJ, Wang B, Losina E, Miura T, Chonco F, van der Stok M, Mncube Z, Bishop K, Goulder PJ, Walker BD, Brockman MA, Ndung'u T.

J Virol. 2010 Oct;84(20):10820-31. doi: 10.1128/JVI.01084-10. Epub 2010 Aug 11.

13.

HIV Controllers Exhibit Enhanced Frequencies of Major Histocompatibility Complex Class II Tetramer+ Gag-Specific CD4+ T Cells in Chronic Clade C HIV-1 Infection.

Laher F, Ranasinghe S, Porichis F, Mewalal N, Pretorius K, Ismail N, Buus S, Stryhn A, Carrington M, Walker BD, Ndung'u T, Ndhlovu ZM.

J Virol. 2017 Mar 13;91(7). pii: e02477-16. doi: 10.1128/JVI.02477-16. Print 2017 Apr 1.

14.

Differential narrow focusing of immunodominant human immunodeficiency virus gag-specific cytotoxic T-lymphocyte responses in infected African and caucasoid adults and children.

Goulder PJ, Brander C, Annamalai K, Mngqundaniso N, Govender U, Tang Y, He S, Hartman KE, O'Callaghan CA, Ogg GS, Altfeld MA, Rosenberg ES, Cao H, Kalams SA, Hammond M, Bunce M, Pelton SI, Burchett SA, McIntosh K, Coovadia HM, Walker BD.

J Virol. 2000 Jun;74(12):5679-90.

15.

Characterization of HIV-specific CD4+ T cell responses against peptides selected with broad population and pathogen coverage.

Buggert M, Norström MM, Czarnecki C, Tupin E, Luo M, Gyllensten K, Sönnerborg A, Lundegaard C, Lund O, Nielsen M, Karlsson AC.

PLoS One. 2012;7(7):e39874. doi: 10.1371/journal.pone.0039874. Epub 2012 Jul 5.

16.

HLA supertypes contribute in HIV type 1 cytotoxic T lymphocyte epitope clustering in Nef and Gag proteins.

Chakraborty S, Rahman T, Chakravorty R, Kuchta A, Rabby A, Sahiuzzaman M.

AIDS Res Hum Retroviruses. 2013 Feb;29(2):270-8. doi: 10.1089/AID.2012.0160. Epub 2013 Jan 8.

PMID:
23061377
17.

Escape and compensation from early HLA-B57-mediated cytotoxic T-lymphocyte pressure on human immunodeficiency virus type 1 Gag alter capsid interactions with cyclophilin A.

Brockman MA, Schneidewind A, Lahaie M, Schmidt A, Miura T, Desouza I, Ryvkin F, Derdeyn CA, Allen S, Hunter E, Mulenga J, Goepfert PA, Walker BD, Allen TM.

J Virol. 2007 Nov;81(22):12608-18. Epub 2007 Aug 29.

18.

Viral evolution in HLA-B27-restricted CTL epitopes in human immunodeficiency virus type 1-infected individuals.

Setiawan LC, Gijsbers EF, van Nuenen AC, Kootstra NA.

J Gen Virol. 2015 Aug;96(8):2372-80. doi: 10.1099/vir.0.000148. Epub 2015 Apr 14.

PMID:
25872744
19.

Cross-reactions between the cytotoxic T-lymphocyte responses of human immunodeficiency virus-infected African and European patients.

Durali D, Morvan J, Letourneur F, Schmitt D, Guegan N, Dalod M, Saragosti S, Sicard D, Levy JP, Gomard E.

J Virol. 1998 May;72(5):3547-53.

20.

Superior control of HIV-1 replication by CD8+ T cells targeting conserved epitopes: implications for HIV vaccine design.

Kunwar P, Hawkins N, Dinges WL, Liu Y, Gabriel EE, Swan DA, Stevens CE, Maenza J, Collier AC, Mullins JI, Hertz T, Yu X, Horton H.

PLoS One. 2013 May 31;8(5):e64405. doi: 10.1371/journal.pone.0064405. Print 2013.

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