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Items: 1 to 20 of 94

1.

Desmoglein-1 regulates esophageal epithelial barrier function and immune responses in eosinophilic esophagitis.

Sherrill JD, Kc K, Wu D, Djukic Z, Caldwell JM, Stucke EM, Kemme KA, Costello MS, Mingler MK, Blanchard C, Collins MH, Abonia JP, Putnam PE, Dellon ES, Orlando RC, Hogan SP, Rothenberg ME.

Mucosal Immunol. 2014 May;7(3):718-29. doi: 10.1038/mi.2013.90. Epub 2013 Nov 13.

2.

Altered esophageal histamine receptor expression in Eosinophilic Esophagitis (EoE): implications on disease pathogenesis.

Merves J, Chandramouleeswaran PM, Benitez AJ, Muir AB, Lee AJ, Lim DM, Dods K, Mehta I, Ruchelli ED, Nakagawa H, Spergel JM, Wang ML.

PLoS One. 2015 Feb 27;10(2):e0114831. doi: 10.1371/journal.pone.0114831. eCollection 2015.

3.

In vitro model for studying esophageal epithelial differentiation and allergic inflammatory responses identifies keratin involvement in eosinophilic esophagitis.

Kc K, Rothenberg ME, Sherrill JD.

PLoS One. 2015 Jun 3;10(6):e0127755. doi: 10.1371/journal.pone.0127755. eCollection 2015.

4.

Elevated IL-33 expression is associated with pediatric eosinophilic esophagitis, and exogenous IL-33 promotes eosinophilic esophagitis development in mice.

Judd LM, Heine RG, Menheniott TR, Buzzelli J, O'Brien-Simpson N, Pavlic D, O'Connor L, Al Gazali K, Hamilton O, Scurr M, Collison AM, Mattes J, Allen KJ, Giraud AS.

Am J Physiol Gastrointest Liver Physiol. 2016 Jan 1;310(1):G13-25. doi: 10.1152/ajpgi.00290.2015. Epub 2015 Oct 29.

5.

Antigen presentation and MHC class II expression by human esophageal epithelial cells: role in eosinophilic esophagitis.

Mulder DJ, Pooni A, Mak N, Hurlbut DJ, Basta S, Justinich CJ.

Am J Pathol. 2011 Feb;178(2):744-53. doi: 10.1016/j.ajpath.2010.10.027.

6.

Preferential Secretion of Thymic Stromal Lymphopoietin (TSLP) by Terminally Differentiated Esophageal Epithelial Cells: Relevance to Eosinophilic Esophagitis (EoE).

Chandramouleeswaran PM, Shen D, Lee AJ, Benitez A, Dods K, Gambanga F, Wilkins BJ, Merves J, Noah Y, Toltzis S, Yearley JH, Spergel JM, Nakagawa H, Malefyt Rd, Muir AB, Wang ML.

PLoS One. 2016 Mar 18;11(3):e0150968. doi: 10.1371/journal.pone.0150968. eCollection 2016.

7.

MicroRNA profiling in mucosal biopsies of eosinophilic esophagitis patients pre and post treatment with steroids and relationship with mRNA targets.

Lu S, Mukkada VA, Mangray S, Cleveland K, Shillingford N, Schorl C, Brodsky AS, Resnick MB.

PLoS One. 2012;7(7):e40676. doi: 10.1371/journal.pone.0040676. Epub 2012 Jul 16.

8.

T-helper 2 cytokines, transforming growth factor β1, and eosinophil products induce fibrogenesis and alter muscle motility in patients with eosinophilic esophagitis.

Rieder F, Nonevski I, Ma J, Ouyang Z, West G, Protheroe C, DePetris G, Schirbel A, Lapinski J, Goldblum J, Bonfield T, Lopez R, Harnett K, Lee J, Hirano I, Falk G, Biancani P, Fiocchi C.

Gastroenterology. 2014 May;146(5):1266-77.e1-9. doi: 10.1053/j.gastro.2014.01.051. Epub 2014 Jan 28.

9.

Analysis and expansion of the eosinophilic esophagitis transcriptome by RNA sequencing.

Sherrill JD, Kiran KC, Blanchard C, Stucke EM, Kemme KA, Collins MH, Abonia JP, Putnam PE, Mukkada VA, Kaul A, Kocoshis SA, Kushner JP, Plassard AJ, Karns RA, Dexheimer PJ, Aronow BJ, Rothenberg ME.

Genes Immun. 2014 Sep;15(6):361-9. doi: 10.1038/gene.2014.27. Epub 2014 Jun 12.

10.

Active eosinophilic esophagitis is characterized by epithelial barrier defects and eosinophil extracellular trap formation.

Simon D, Radonjic-Hösli S, Straumann A, Yousefi S, Simon HU.

Allergy. 2015 Apr;70(4):443-52. doi: 10.1111/all.12570. Epub 2015 Jan 26.

11.

Intravenous anti-IL-13 mAb QAX576 for the treatment of eosinophilic esophagitis.

Rothenberg ME, Wen T, Greenberg A, Alpan O, Enav B, Hirano I, Nadeau K, Kaiser S, Peters T, Perez A, Jones I, Arm JP, Strieter RM, Sabo R, Gunawardena KA.

J Allergy Clin Immunol. 2015 Feb;135(2):500-7. doi: 10.1016/j.jaci.2014.07.049. Epub 2014 Sep 13.

PMID:
25226850
12.

Plakoglobin rescues adhesive defects induced by ectodomain truncation of the desmosomal cadherin desmoglein 1: implications for exfoliative toxin-mediated skin blistering.

Simpson CL, Kojima S, Cooper-Whitehair V, Getsios S, Green KJ.

Am J Pathol. 2010 Dec;177(6):2921-37. doi: 10.2353/ajpath.2010.100397. Epub 2010 Nov 12.

13.

Transcriptome analysis of proton pump inhibitor-responsive esophageal eosinophilia reveals proton pump inhibitor-reversible allergic inflammation.

Wen T, Dellon ES, Moawad FJ, Furuta GT, Aceves SS, Rothenberg ME.

J Allergy Clin Immunol. 2015 Jan;135(1):187-97. doi: 10.1016/j.jaci.2014.08.043. Epub 2014 Oct 19.

14.

Neurotrophic tyrosine kinase receptor 1 is a direct transcriptional and epigenetic target of IL-13 involved in allergic inflammation.

Rochman M, Kartashov AV, Caldwell JM, Collins MH, Stucke EM, Kc K, Sherrill JD, Herren J, Barski A, Rothenberg ME.

Mucosal Immunol. 2015 Jul;8(4):785-98. doi: 10.1038/mi.2014.109. Epub 2014 Nov 12.

15.

MiR-375 is downregulated in epithelial cells after IL-13 stimulation and regulates an IL-13-induced epithelial transcriptome.

Lu TX, Lim EJ, Wen T, Plassard AJ, Hogan SP, Martin LJ, Aronow BJ, Rothenberg ME.

Mucosal Immunol. 2012 Jul;5(4):388-96. doi: 10.1038/mi.2012.16. Epub 2012 Mar 28.

16.

Desmoglein-1/Erbin interaction suppresses ERK activation to support epidermal differentiation.

Harmon RM, Simpson CL, Johnson JL, Koetsier JL, Dubash AD, Najor NA, Sarig O, Sprecher E, Green KJ.

J Clin Invest. 2013 Apr;123(4):1556-70. doi: 10.1172/JCI65220. Epub 2013 Mar 25.

17.

Proton pump inhibitors partially restore mucosal integrity in patients with proton pump inhibitor-responsive esophageal eosinophilia but not eosinophilic esophagitis.

van Rhijn BD, Weijenborg PW, Verheij J, van den Bergh Weerman MA, Verseijden C, van den Wijngaard RM, de Jonge WJ, Smout AJ, Bredenoord AJ.

Clin Gastroenterol Hepatol. 2014 Nov;12(11):1815-23.e2. doi: 10.1016/j.cgh.2014.02.037. Epub 2014 Mar 19.

PMID:
24657840
18.

MicroRNA signature in patients with eosinophilic esophagitis, reversibility with glucocorticoids, and assessment as disease biomarkers.

Lu TX, Sherrill JD, Wen T, Plassard AJ, Besse JA, Abonia JP, Franciosi JP, Putnam PE, Eby M, Martin LJ, Aronow BJ, Rothenberg ME.

J Allergy Clin Immunol. 2012 Apr;129(4):1064-75.e9. doi: 10.1016/j.jaci.2012.01.060. Epub 2012 Mar 3.

19.

Transient PPI responsive esophageal eosinophilia may be a clinical sub-phenotype of pediatric eosinophilic esophagitis.

Dohil R, Newbury RO, Aceves S.

Dig Dis Sci. 2012 May;57(5):1413-9. doi: 10.1007/s10620-011-1991-5. Epub 2011 Dec 2.

PMID:
22134787
20.

Allergen-induced resistin-like molecule-α promotes esophageal epithelial cell hyperplasia in eosinophilic esophagitis.

Mavi P, Niranjan R, Dutt P, Zaidi A, Shukla JS, Korfhagen T, Mishra A.

Am J Physiol Gastrointest Liver Physiol. 2014 Sep 1;307(5):G499-507. doi: 10.1152/ajpgi.00141.2014. Epub 2014 Jul 3. Erratum in: Am J Physiol Gastrointest Liver Physiol. 2015 Aug 15;309(4):G281.

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