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Items: 1 to 20 of 235

1.

Evidence for a regulatory role of Cullin-RING E3 ubiquitin ligase 7 in insulin signaling.

Scheufele F, Wolf B, Kruse M, Hartmann T, Lempart J, Muehlich S, Pfeiffer AF, Field LJ, Charron MJ, Pan ZQ, Engelhardt S, Sarikas A.

Cell Signal. 2014 Feb;26(2):233-9. doi: 10.1016/j.cellsig.2013.11.005. Epub 2013 Nov 9.

2.

The CUL7 E3 ubiquitin ligase targets insulin receptor substrate 1 for ubiquitin-dependent degradation.

Xu X, Sarikas A, Dias-Santagata DC, Dolios G, Lafontant PJ, Tsai SC, Zhu W, Nakajima H, Nakajima HO, Field LJ, Wang R, Pan ZQ.

Mol Cell. 2008 May 23;30(4):403-14. doi: 10.1016/j.molcel.2008.03.009.

3.

Inhibition of Cullin-RING E3 ubiquitin ligase 7 by simian virus 40 large T antigen.

Hartmann T, Xu X, Kronast M, Muehlich S, Meyer K, Zimmermann W, Hurwitz J, Pan ZQ, Engelhardt S, Sarikas A.

Proc Natl Acad Sci U S A. 2014 Mar 4;111(9):3371-6. doi: 10.1073/pnas.1401556111. Epub 2014 Feb 18.

4.

The CUL7/F-box and WD repeat domain containing 8 (CUL7/Fbxw8) ubiquitin ligase promotes degradation of hematopoietic progenitor kinase 1.

Wang H, Chen Y, Lin P, Li L, Zhou G, Liu G, Logsdon C, Jin J, Abbruzzese JL, Tan TH, Wang H.

J Biol Chem. 2014 Feb 14;289(7):4009-17. doi: 10.1074/jbc.M113.520106. Epub 2013 Dec 20.

5.

Characterization of the Cullin7 E3 ubiquitin ligase--heterodimerization of cullin substrate receptors as a novel mechanism to regulate cullin E3 ligase activity.

Ponyeam W, Hagen T.

Cell Signal. 2012 Jan;24(1):290-5. doi: 10.1016/j.cellsig.2011.08.020. Epub 2011 Sep 16.

PMID:
21946088
6.

Identification of the degradation determinants of insulin receptor substrate 1 for signaling cullin-RING E3 ubiquitin ligase 7-mediated ubiquitination.

Xu X, Keshwani M, Meyer K, Sarikas A, Taylor S, Pan ZQ.

J Biol Chem. 2012 Nov 23;287(48):40758-66. doi: 10.1074/jbc.M112.405209. Epub 2012 Oct 8.

7.

Myostatin reduces Akt/TORC1/p70S6K signaling, inhibiting myoblast differentiation and myotube size.

Trendelenburg AU, Meyer A, Rohner D, Boyle J, Hatakeyama S, Glass DJ.

Am J Physiol Cell Physiol. 2009 Jun;296(6):C1258-70. doi: 10.1152/ajpcell.00105.2009. Epub 2009 Apr 8.

8.

The cullin7 E3 ubiquitin ligase: a novel player in growth control.

Sarikas A, Xu X, Field LJ, Pan ZQ.

Cell Cycle. 2008 Oct;7(20):3154-61. Epub 2008 Oct 4. Review.

9.

Serine 302 Phosphorylation of Mouse Insulin Receptor Substrate 1 (IRS1) Is Dispensable for Normal Insulin Signaling and Feedback Regulation by Hepatic S6 Kinase.

Copps KD, Hançer NJ, Qiu W, White MF.

J Biol Chem. 2016 Apr 15;291(16):8602-17. doi: 10.1074/jbc.M116.714915. Epub 2016 Feb 4.

10.

A Cullin1-based SCF E3 ubiquitin ligase targets the InR/PI3K/TOR pathway to regulate neuronal pruning.

Wong JJ, Li S, Lim EK, Wang Y, Wang C, Zhang H, Kirilly D, Wu C, Liou YC, Wang H, Yu F.

PLoS Biol. 2013 Sep;11(9):e1001657. doi: 10.1371/journal.pbio.1001657. Epub 2013 Sep 17.

11.

Ataxia telangiectasia mutated impacts insulin-like growth factor 1 signalling in skeletal muscle.

Ching JK, Luebbert SH, Collins RL 4th, Zhang Z, Marupudi N, Banerjee S, Hurd RD, Ralston L, Fisher JS.

Exp Physiol. 2013 Feb;98(2):526-35. doi: 10.1113/expphysiol.2012.066357. Epub 2012 Aug 31.

12.

mTOR complex 2 regulates proper turnover of insulin receptor substrate-1 via the ubiquitin ligase subunit Fbw8.

Kim SJ, DeStefano MA, Oh WJ, Wu CC, Vega-Cotto NM, Finlan M, Liu D, Su B, Jacinto E.

Mol Cell. 2012 Dec 28;48(6):875-87. doi: 10.1016/j.molcel.2012.09.029. Epub 2012 Nov 8.

13.
14.

Cardiac PI3K-Akt impairs insulin-stimulated glucose uptake independent of mTORC1 and GLUT4 translocation.

Zhu Y, Pereira RO, O'Neill BT, Riehle C, Ilkun O, Wende AR, Rawlings TA, Zhang YC, Zhang Q, Klip A, Shiojima I, Walsh K, Abel ED.

Mol Endocrinol. 2013 Jan;27(1):172-84. doi: 10.1210/me.2012-1210. Epub 2012 Nov 30.

15.

AMPD1 regulates mTORC1-p70 S6 kinase axis in the control of insulin sensitivity in skeletal muscle.

Tandelilin AA, Hirase T, Hudoyo AW, Cheng J, Toyama K, Morisaki H, Morisaki T.

BMC Endocr Disord. 2015 Mar 27;15:11. doi: 10.1186/s12902-015-0010-9. Erratum in: BMC Endocr Disord. 2015;15:80.

16.

PARC and CUL7 form atypical cullin RING ligase complexes.

Skaar JR, Florens L, Tsutsumi T, Arai T, Tron A, Swanson SK, Washburn MP, DeCaprio JA.

Cancer Res. 2007 Mar 1;67(5):2006-14.

17.

Chronic inhibition of the mTORC1/S6K1 pathway increases insulin-induced PI3K activity but inhibits Akt2 and glucose transport stimulation in 3T3-L1 adipocytes.

Veilleux A, Houde VP, Bellmann K, Marette A.

Mol Endocrinol. 2010 Apr;24(4):766-78. doi: 10.1210/me.2009-0328. Epub 2010 Mar 4.

18.

Genetically engineered mouse models for functional studies of SKP1-CUL1-F-box-protein (SCF) E3 ubiquitin ligases.

Zhou W, Wei W, Sun Y.

Cell Res. 2013 May;23(5):599-619. doi: 10.1038/cr.2013.44. Epub 2013 Mar 26. Review.

19.

Skeletal muscle protein balance in mTOR heterozygous mice in response to inflammation and leucine.

Lang CH, Frost RA, Bronson SK, Lynch CJ, Vary TC.

Am J Physiol Endocrinol Metab. 2010 Jun;298(6):E1283-94. doi: 10.1152/ajpendo.00676.2009. Epub 2010 Apr 13.

20.

β-Adrenergic receptor-PI3K signaling crosstalk in mouse heart: elucidation of immediate downstream signaling cascades.

Zhang W, Yano N, Deng M, Mao Q, Shaw SK, Tseng YT.

PLoS One. 2011;6(10):e26581. doi: 10.1371/journal.pone.0026581. Epub 2011 Oct 19.

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