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Items: 1 to 20 of 188

1.

Naive and memory human B cells have distinct requirements for STAT3 activation to differentiate into antibody-secreting plasma cells.

Deenick EK, Avery DT, Chan A, Berglund LJ, Ives ML, Moens L, Stoddard JL, Bustamante J, Boisson-Dupuis S, Tsumura M, Kobayashi M, Arkwright PD, Averbuch D, Engelhard D, Roesler J, Peake J, Wong M, Adelstein S, Choo S, Smart JM, French MA, Fulcher DA, Cook MC, Picard C, Durandy A, Klein C, Holland SM, Uzel G, Casanova JL, Ma CS, Tangye SG.

J Exp Med. 2013 Nov 18;210(12):2739-53. doi: 10.1084/jem.20130323. Epub 2013 Nov 11.

2.

B cell-intrinsic signaling through IL-21 receptor and STAT3 is required for establishing long-lived antibody responses in humans.

Avery DT, Deenick EK, Ma CS, Suryani S, Simpson N, Chew GY, Chan TD, Palendira U, Bustamante J, Boisson-Dupuis S, Choo S, Bleasel KE, Peake J, King C, French MA, Engelhard D, Al-Hajjar S, Al-Muhsen S, Magdorf K, Roesler J, Arkwright PD, Hissaria P, Riminton DS, Wong M, Brink R, Fulcher DA, Casanova JL, Cook MC, Tangye SG.

J Exp Med. 2010 Jan 18;207(1):155-71. doi: 10.1084/jem.20091706. Epub 2010 Jan 4.

3.

IL-21 signalling via STAT3 primes human naive B cells to respond to IL-2 to enhance their differentiation into plasmablasts.

Berglund LJ, Avery DT, Ma CS, Moens L, Deenick EK, Bustamante J, Boisson-Dupuis S, Wong M, Adelstein S, Arkwright PD, Bacchetta R, Bezrodnik L, Dadi H, Roifman CM, Fulcher DA, Ziegler JB, Smart JM, Kobayashi M, Picard C, Durandy A, Cook MC, Casanova JL, Uzel G, Tangye SG.

Blood. 2013 Dec 5;122(24):3940-50. doi: 10.1182/blood-2013-06-506865. Epub 2013 Oct 24.

4.

Signal transducer and activator of transcription 3 (STAT3) mutations underlying autosomal dominant hyper-IgE syndrome impair human CD8(+) T-cell memory formation and function.

Ives ML, Ma CS, Palendira U, Chan A, Bustamante J, Boisson-Dupuis S, Arkwright PD, Engelhard D, Averbuch D, Magdorf K, Roesler J, Peake J, Wong M, Adelstein S, Choo S, Smart JM, French MA, Fulcher DA, Cook MC, Picard C, Durandy A, Tsumura M, Kobayashi M, Uzel G, Casanova JL, Tangye SG, Deenick EK.

J Allergy Clin Immunol. 2013 Aug;132(2):400-11.e9. doi: 10.1016/j.jaci.2013.05.029. Epub 2013 Jul 4.

5.

Functional STAT3 deficiency compromises the generation of human T follicular helper cells.

Ma CS, Avery DT, Chan A, Batten M, Bustamante J, Boisson-Dupuis S, Arkwright PD, Kreins AY, Averbuch D, Engelhard D, Magdorf K, Kilic SS, Minegishi Y, Nonoyama S, French MA, Choo S, Smart JM, Peake J, Wong M, Gray P, Cook MC, Fulcher DA, Casanova JL, Deenick EK, Tangye SG.

Blood. 2012 Apr 26;119(17):3997-4008. doi: 10.1182/blood-2011-11-392985. Epub 2012 Mar 8.

6.

B-cell memory and primary immune deficiencies: interleukin-21 related defects.

Desjardins M, Mazer BD.

Curr Opin Allergy Clin Immunol. 2013 Dec;13(6):639-45. doi: 10.1097/ACI.0000000000000009. Review.

PMID:
24126614
8.

Interleukin-21 maintains the expression of CD16 on monocytes via the production of IL-10 by human naïve CD4+ T cells.

Liu Y, Yang B, Ma J, Wang H, Huang F, Zhang J, Chen H, Wu C.

Cell Immunol. 2011;267(2):102-8. doi: 10.1016/j.cellimm.2010.12.003. Epub 2010 Dec 19.

PMID:
21227406
9.

Regulation of B-cell commitment to plasma cells or to memory B cells.

Liu YJ, Banchereau J.

Semin Immunol. 1997 Aug;9(4):235-40. Review.

PMID:
9237929
10.

IFN-alpha amplifies human naive B cell TLR-9-mediated activation and Ig production.

Giordani L, Sanchez M, Libri I, Quaranta MG, Mattioli B, Viora M.

J Leukoc Biol. 2009 Aug;86(2):261-71. doi: 10.1189/jlb.0908560. Epub 2009 Apr 28.

PMID:
19401392
11.

Essential role of IL-21 in B cell activation, expansion, and plasma cell generation during CD4+ T cell-B cell collaboration.

Kuchen S, Robbins R, Sims GP, Sheng C, Phillips TM, Lipsky PE, Ettinger R.

J Immunol. 2007 Nov 1;179(9):5886-96.

12.

Increased expression of CD27 on activated human memory B cells correlates with their commitment to the plasma cell lineage.

Avery DT, Ellyard JI, Mackay F, Corcoran LM, Hodgkin PD, Tangye SG.

J Immunol. 2005 Apr 1;174(7):4034-42. Erratum in: J Immunol. 2005 May 1;174(9):5885.

13.
14.

IL-21 and IL-10 have redundant roles but differential capacities at different stages of Plasma Cell generation from human Germinal Center B cells.

Yoon SO, Zhang X, Berner P, Choi YS.

J Leukoc Biol. 2009 Dec;86(6):1311-8. doi: 10.1189/jlb.0409268. Epub 2009 Sep 17.

PMID:
19762555
15.

STAT3-mediated up-regulation of BLIMP1 Is coordinated with BCL6 down-regulation to control human plasma cell differentiation.

Diehl SA, Schmidlin H, Nagasawa M, van Haren SD, Kwakkenbos MJ, Yasuda E, Beaumont T, Scheeren FA, Spits H.

J Immunol. 2008 Apr 1;180(7):4805-15.

16.

Autocrine IL-10 promotes human B-cell differentiation into IgM- or IgG-secreting plasmablasts.

Heine G, Drozdenko G, Grün JR, Chang HD, Radbruch A, Worm M.

Eur J Immunol. 2014 Jun;44(6):1615-21. doi: 10.1002/eji.201343822. Epub 2014 Mar 11.

17.

An interleukin-21-interleukin-10-STAT3 pathway is critical for functional maturation of memory CD8+ T cells.

Cui W, Liu Y, Weinstein JS, Craft J, Kaech SM.

Immunity. 2011 Nov 23;35(5):792-805. doi: 10.1016/j.immuni.2011.09.017.

18.

IL-21 and CD40L synergistically promote plasma cell differentiation through upregulation of Blimp-1 in human B cells.

Ding BB, Bi E, Chen H, Yu JJ, Ye BH.

J Immunol. 2013 Feb 15;190(4):1827-36. doi: 10.4049/jimmunol.1201678. Epub 2013 Jan 16.

19.

STAT-3 activation by differential cytokines is critical for human in vivo-generated plasma cell survival and Ig secretion.

Rodríguez-Bayona B, Ramos-Amaya A, López-Blanco R, Campos-Caro A, Brieva JA.

J Immunol. 2013 Nov 15;191(10):4996-5004. doi: 10.4049/jimmunol.1301559. Epub 2013 Oct 7.

20.

Decreased expression of interleukin-21 receptor on peripheral B lymphocytes in systemic lupus erythematosus.

Mitoma H, Horiuchi T, Kimoto Y, Tsukamoto H, Uchino A, Tamimoto Y, Miyagi Y, Harada M.

Int J Mol Med. 2005 Oct;16(4):609-15.

PMID:
16142394

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