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Items: 1 to 20 of 107

1.

Receptor protein-tyrosine phosphatase α regulates focal adhesion kinase phosphorylation and ErbB2 oncoprotein-mediated mammary epithelial cell motility.

Boivin B, Chaudhary F, Dickinson BC, Haque A, Pero SC, Chang CJ, Tonks NK.

J Biol Chem. 2013 Dec 27;288(52):36926-35. doi: 10.1074/jbc.M113.527564. Epub 2013 Nov 11.

2.

Grb2 promotes integrin-induced focal adhesion kinase (FAK) autophosphorylation and directs the phosphorylation of protein tyrosine phosphatase α by the Src-FAK kinase complex.

Cheng SY, Sun G, Schlaepfer DD, Pallen CJ.

Mol Cell Biol. 2014 Feb;34(3):348-61. doi: 10.1128/MCB.00825-13. Epub 2013 Nov 18.

3.

Protein tyrosine phosphatase-alpha complexes with the IGF-I receptor and undergoes IGF-I-stimulated tyrosine phosphorylation that mediates cell migration.

Chen SC, Khanna RS, Bessette DC, Samayawardhena LA, Pallen CJ.

Am J Physiol Cell Physiol. 2009 Jul;297(1):C133-9. doi: 10.1152/ajpcell.00110.2009. Epub 2009 May 6.

4.
6.

The Ste20-like kinase SLK is required for ErbB2-driven breast cancer cell motility.

Roovers K, Wagner S, Storbeck CJ, O'Reilly P, Lo V, Northey JJ, Chmielecki J, Muller WJ, Siegel PM, Sabourin LA.

Oncogene. 2009 Aug 6;28(31):2839-48. doi: 10.1038/onc.2009.146. Epub 2009 Jun 15.

PMID:
19525980
7.

Protein tyrosine phosphatase α phosphotyrosyl-789 binds BCAR3 to position Cas for activation at integrin-mediated focal adhesions.

Sun G, Cheng SY, Chen M, Lim CJ, Pallen CJ.

Mol Cell Biol. 2012 Sep;32(18):3776-89. doi: 10.1128/MCB.00214-12. Epub 2012 Jul 16.

8.

Protein-tyrosine phosphatase alpha acts as an upstream regulator of Fyn signaling to promote oligodendrocyte differentiation and myelination.

Wang PS, Wang J, Xiao ZC, Pallen CJ.

J Biol Chem. 2009 Nov 27;284(48):33692-702. doi: 10.1074/jbc.M109.061770. Epub 2009 Oct 6.

9.

Interactions of the protein-tyrosine phosphatase-α with the focal adhesion targeting domain of focal adhesion kinase are involved in interleukin-1 signaling in fibroblasts.

Wang Q, Wang Y, Fritz D, Rajshankar D, Downey GP, McCulloch CA.

J Biol Chem. 2014 Jun 27;289(26):18427-41. doi: 10.1074/jbc.M113.540294. Epub 2014 May 12.

10.

Focal adhesion kinase regulates the phosphorylation protein tyrosine phosphatase-α at Tyr789 in breast cancer cells.

Fang XQ, Liu XF, Yao L, Chen CQ, Lin JF, Gu ZD, Ni PH, Zheng XM, Fan QS.

Mol Med Rep. 2015 Jun;11(6):4303-8. doi: 10.3892/mmr.2015.3262. Epub 2015 Jan 27.

PMID:
25625869
11.

Protein-tyrosine phosphatase alpha regulates Src family kinases and alters cell-substratum adhesion.

Harder KW, Moller NP, Peacock JW, Jirik FR.

J Biol Chem. 1998 Nov 27;273(48):31890-900.

12.
13.

ErbB2 requires integrin alpha5 for anoikis resistance via Src regulation of receptor activity in human mammary epithelial cells.

Haenssen KK, Caldwell SA, Shahriari KS, Jackson SR, Whelan KA, Klein-Szanto AJ, Reginato MJ.

J Cell Sci. 2010 Apr 15;123(Pt 8):1373-82. doi: 10.1242/jcs.050906. Epub 2010 Mar 23.

14.

Expression profiling during mammary epithelial cell three-dimensional morphogenesis identifies PTPRO as a novel regulator of morphogenesis and ErbB2-mediated transformation.

Yu M, Lin G, Arshadi N, Kalatskaya I, Xue B, Haider S, Nguyen F, Boutros PC, Elson A, Muthuswamy LB, Tonks NK, Muthuswamy SK.

Mol Cell Biol. 2012 Oct;32(19):3913-24. doi: 10.1128/MCB.00068-12. Epub 2012 Jul 30.

15.

Tyrosine phosphatase PTPα contributes to HER2-evoked breast tumor initiation and maintenance.

Meyer DS, Aceto N, Sausgruber N, Brinkhaus H, Müller U, Pallen CJ, Bentires-Alj M.

Oncogene. 2014 Jan 16;33(3):398-402. doi: 10.1038/onc.2012.585. Epub 2013 Jan 14.

PMID:
23318421
16.

β1,6 GlcNAc branches-modified protein tyrosine phosphatase alpha enhances its stability and promotes focal adhesion formation in MCF-7 cells.

Xiao J, Gao Y, Yang F, Wang C, Xu Y, Chang R, Zha X, Wang L.

Biochem Biophys Res Commun. 2017 Jan 22;482(4):1455-1461. doi: 10.1016/j.bbrc.2016.12.057. Epub 2016 Dec 10.

PMID:
27965091
17.

Integrin-associated CD151 drives ErbB2-evoked mammary tumor onset and metastasis.

Deng X, Li Q, Hoff J, Novak M, Yang H, Jin H, Erfani SF, Sharma C, Zhou P, Rabinovitz I, Sonnenberg A, Yi Y, Zhou P, Stipp CS, Kaetzel DM, Hemler ME, Yang XH.

Neoplasia. 2012 Aug;14(8):678-89.

18.

A ternary complex comprising FAK, PTPα and IP3 receptor 1 functionally engages focal adhesions and the endoplasmic reticulum to mediate IL-1-induced Ca2+ signalling in fibroblasts.

Wang Q, Wang Y, Downey GP, Plotnikov S, McCulloch CA.

Biochem J. 2016 Feb 15;473(4):397-410. doi: 10.1042/BJ20150907. Epub 2015 Nov 26.

PMID:
26611753
19.

Identification of PTPN23 as a novel regulator of cell invasion in mammary epithelial cells from a loss-of-function screen of the 'PTP-ome'.

Lin G, Aranda V, Muthuswamy SK, Tonks NK.

Genes Dev. 2011 Jul 1;25(13):1412-25. doi: 10.1101/gad.2018911.

20.

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