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Items: 1 to 20 of 114

1.

Human cytomegalovirus (HCMV) US2 protein interacts with human CD1d (hCD1d) and down-regulates invariant NKT (iNKT) cell activity.

Han J, Rho SB, Lee JY, Bae J, Park SH, Lee SJ, Lee SY, Ahn C, Kim JY, Chun T.

Mol Cells. 2013 Nov;36(5):455-64. doi: 10.1007/s10059-013-0221-8. Epub 2013 Nov 8.

2.

Human CD1d molecules are resistant to human cytomegalovirus US2- and US11-mediated degradation.

Cho S, Jun Y.

Biochem Biophys Res Commun. 2011 Oct 7;413(4):616-22. doi: 10.1016/j.bbrc.2011.09.013. Epub 2011 Sep 6.

PMID:
21925141
3.

Subtle sequence variation among MHC class I locus products greatly influences sensitivity to HCMV US2- and US11-mediated degradation.

Barel MT, Pizzato N, Le Bouteiller P, Wiertz EJ, Lenfant F.

Int Immunol. 2006 Jan;18(1):173-82. Epub 2005 Dec 16.

PMID:
16361314
4.

Human cytomegalovirus-encoded US2 differentially affects surface expression of MHC class I locus products and targets membrane-bound, but not soluble HLA-G1 for degradation.

Barel MT, Ressing M, Pizzato N, van Leeuwen D, Le Bouteiller P, Lenfant F, Wiertz EJ.

J Immunol. 2003 Dec 15;171(12):6757-65.

5.

Binding of human cytomegalovirus US2 to major histocompatibility complex class I and II proteins is not sufficient for their degradation.

Chevalier MS, Daniels GM, Johnson DC.

J Virol. 2002 Aug;76(16):8265-75. Erratum in: J Virol 2002 Dec;76(24):13126.

6.

Signal peptide peptidase is required for dislocation from the endoplasmic reticulum.

Loureiro J, Lilley BN, Spooner E, Noriega V, Tortorella D, Ploegh HL.

Nature. 2006 Jun 15;441(7095):894-7. Epub 2006 May 31.

PMID:
16738546
8.
10.

Identifying the ERAD ubiquitin E3 ligases for viral and cellular targeting of MHC class I.

van den Boomen DJ, Lehner PJ.

Mol Immunol. 2015 Dec;68(2 Pt A):106-11. doi: 10.1016/j.molimm.2015.07.005. Epub 2015 Jul 22. Review.

11.

Antigen presentation and the ubiquitin-proteasome system in host-pathogen interactions.

Loureiro J, Ploegh HL.

Adv Immunol. 2006;92:225-305. Review.

PMID:
17145306
12.

Cytomegalovirus US2 destroys two components of the MHC class II pathway, preventing recognition by CD4+ T cells.

Tomazin R, Boname J, Hegde NR, Lewinsohn DM, Altschuler Y, Jones TR, Cresswell P, Nelson JA, Riddell SR, Johnson DC.

Nat Med. 1999 Sep;5(9):1039-43.

PMID:
10470081
13.
14.

NK cell activity during human cytomegalovirus infection is dominated by US2-11-mediated HLA class I down-regulation.

Falk CS, Mach M, Schendel DJ, Weiss EH, Hilgert I, Hahn G.

J Immunol. 2002 Sep 15;169(6):3257-66.

15.

A single viral protein HCMV US2 affects antigen presentation and intracellular iron homeostasis by degradation of classical HLA class I and HFE molecules.

Vahdati-Ben Arieh S, Laham N, Schechter C, Yewdell JW, Coligan JE, Ehrlich R.

Blood. 2003 Apr 1;101(7):2858-64. Epub 2002 Nov 27.

16.

Inhibition of the MHC class II antigen presentation pathway by human cytomegalovirus.

Johnson DC, Hegde NR.

Curr Top Microbiol Immunol. 2002;269:101-15. Review.

PMID:
12224504
17.

Human cytomegalovirus-encoded immune modulators partner to downregulate major histocompatibility complex class I molecules.

Noriega VM, Tortorella D.

J Virol. 2009 Feb;83(3):1359-67. doi: 10.1128/JVI.01324-08. Epub 2008 Nov 12.

18.

Human cytomegalovirus gene products US2 and US11 differ in their ability to attack major histocompatibility class I heavy chains in dendritic cells.

Rehm A, Engelsberg A, Tortorella D, Körner IJ, Lehmann I, Ploegh HL, Höpken UE.

J Virol. 2002 May;76(10):5043-50.

19.

Antigen presentation subverted: Structure of the human cytomegalovirus protein US2 bound to the class I molecule HLA-A2.

Gewurz BE, Gaudet R, Tortorella D, Wang EW, Ploegh HL, Wiley DC.

Proc Natl Acad Sci U S A. 2001 Jun 5;98(12):6794-9.

20.

Rhesus cytomegalovirus contains functional homologues of US2, US3, US6, and US11.

Pande NT, Powers C, Ahn K, Früh K.

J Virol. 2005 May;79(9):5786-98.

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