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Items: 1 to 20 of 251

1.

Tumor necrosis factor receptor signaling in keratinocytes triggers interleukin-24-dependent psoriasis-like skin inflammation in mice.

Kumari S, Bonnet MC, Ulvmar MH, Wolk K, Karagianni N, Witte E, Uthoff-Hachenberg C, Renauld JC, Kollias G, Toftgard R, Sabat R, Pasparakis M, Haase I.

Immunity. 2013 Nov 14;39(5):899-911. doi: 10.1016/j.immuni.2013.10.009. Epub 2013 Nov 7.

2.

IL-22 and IL-20 are key mediators of the epidermal alterations in psoriasis while IL-17 and IFN-gamma are not.

Wolk K, Haugen HS, Xu W, Witte E, Waggie K, Anderson M, Vom Baur E, Witte K, Warszawska K, Philipp S, Johnson-Leger C, Volk HD, Sterry W, Sabat R.

J Mol Med (Berl). 2009 May;87(5):523-36. doi: 10.1007/s00109-009-0457-0. Epub 2009 Mar 30.

PMID:
19330474
3.

Psoriasis and other Th17-mediated skin diseases.

Tokura Y, Mori T, Hino R.

J UOEH. 2010 Dec 1;32(4):317-28. Review.

PMID:
21226422
4.

Skin lesion development in a mouse model of incontinentia pigmenti is triggered by NEMO deficiency in epidermal keratinocytes and requires TNF signaling.

Nenci A, Huth M, Funteh A, Schmidt-Supprian M, Bloch W, Metzger D, Chambon P, Rajewsky K, Krieg T, Haase I, Pasparakis M.

Hum Mol Genet. 2006 Feb 15;15(4):531-42. Epub 2006 Jan 6.

PMID:
16399796
5.

Apurinic/apyrimidinic endonuclease 1 is a key modulator of keratinocyte inflammatory responses.

Lee HM, Yuk JM, Shin DM, Yang CS, Kim KK, Choi DK, Liang ZL, Kim JM, Jeon BH, Kim CD, Lee JH, Jo EK.

J Immunol. 2009 Nov 15;183(10):6839-48. doi: 10.4049/jimmunol.0901856. Epub 2009 Oct 21.

6.

Picea mariana polyphenolic extract inhibits phlogogenic mediators produced by TNF-α-activated psoriatic keratinocytes: Impact on NF-κB pathway.

García-Pérez ME, Allaeys I, Rusu D, Pouliot R, Janezic TS, Poubelle PE.

J Ethnopharmacol. 2014;151(1):265-78. doi: 10.1016/j.jep.2013.10.034. Epub 2013 Nov 1.

PMID:
24189030
7.

IL-20: a new target for the treatment of inflammatory skin disease.

Rich BE.

Expert Opin Ther Targets. 2003 Apr;7(2):165-74. Review.

PMID:
12667095
8.

Tumor necrosis factor-alpha regulates inflammatory and mesenchymal responses via mitogen-activated protein kinase kinase, p38, and nuclear factor kappaB in human endometriotic epithelial cells.

Grund EM, Kagan D, Tran CA, Zeitvogel A, Starzinski-Powitz A, Nataraja S, Palmer SS.

Mol Pharmacol. 2008 May;73(5):1394-404. doi: 10.1124/mol.107.042176. Epub 2008 Feb 5.

9.

Avarol inhibits TNF-alpha generation and NF-kappaB activation in human cells and in animal models.

Amigó M, Payá M, Braza-Boïls A, De Rosa S, Terencio MC.

Life Sci. 2008 Jan 30;82(5-6):256-64. doi: 10.1016/j.lfs.2007.11.017. Epub 2007 Dec 5.

PMID:
18177902
10.

Interleukin 17 drives vascular inflammation, endothelial dysfunction, and arterial hypertension in psoriasis-like skin disease.

Karbach S, Croxford AL, Oelze M, Schüler R, Minwegen D, Wegner J, Koukes L, Yogev N, Nikolaev A, Reißig S, Ullmann A, Knorr M, Waldner M, Neurath MF, Li H, Wu Z, Brochhausen C, Scheller J, Rose-John S, Piotrowski C, Bechmann I, Radsak M, Wild P, Daiber A, von Stebut E, Wenzel P, Waisman A, Münzel T.

Arterioscler Thromb Vasc Biol. 2014 Dec;34(12):2658-68. doi: 10.1161/ATVBAHA.114.304108. Epub 2014 Oct 23.

11.

IL-17 and IL-22 mediate IL-20 subfamily cytokine production in cultured keratinocytes via increased IL-22 receptor expression.

Tohyama M, Hanakawa Y, Shirakata Y, Dai X, Yang L, Hirakawa S, Tokumaru S, Okazaki H, Sayama K, Hashimoto K.

Eur J Immunol. 2009 Oct;39(10):2779-88. doi: 10.1002/eji.200939473.

12.

Increased βTrCP are associated with imiquimod-induced psoriasis-like skin inflammation in mice via NF-κB signaling pathway.

Li R, Wang J, Wang X, Zhou J, Wang M, Ma H, Xiao S.

Gene. 2016 Oct 30;592(1):164-71. doi: 10.1016/j.gene.2016.07.066. Epub 2016 Jul 28.

PMID:
27476970
13.

Repression of inflammatory gene expression in human pulmonary epithelial cells by small-molecule IkappaB kinase inhibitors.

Newton R, Holden NS, Catley MC, Oyelusi W, Leigh R, Proud D, Barnes PJ.

J Pharmacol Exp Ther. 2007 May;321(2):734-42. Epub 2007 Feb 22.

14.
15.

Reactive oxygen species in tumor necrosis factor-alpha-activated primary human keratinocytes: implications for psoriasis and inflammatory skin disease.

Young CN, Koepke JI, Terlecky LJ, Borkin MS, Boyd Savoy L, Terlecky SR.

J Invest Dermatol. 2008 Nov;128(11):2606-14. doi: 10.1038/jid.2008.122. Epub 2008 May 8. Erratum in: J Invest Dermatol. 2009 Jul;129(7):1838. Boyd, Savoy L [corrected to Boyd Savoy, L].

16.

Proinflammatory cytokines, IL-1β and TNF-α, induce expression of interleukin-34 mRNA via JNK- and p44/42 MAPK-NF-κB pathway but not p38 pathway in osteoblasts.

Eda H, Shimada H, Beidler DR, Monahan JB.

Rheumatol Int. 2011 Nov;31(11):1525-30. doi: 10.1007/s00296-010-1688-7. Epub 2010 Dec 23.

PMID:
21181166
17.
18.

A role for mitogen-activated protein kinase activation by integrins in the pathogenesis of psoriasis.

Haase I, Hobbs RM, Romero MR, Broad S, Watt FM.

J Clin Invest. 2001 Aug;108(4):527-36.

19.

NF-κB and STAT3 inhibition as a therapeutic strategy in psoriasis: in vitro and in vivo effects of BTH.

Andrés RM, Montesinos MC, Navalón P, Payá M, Terencio MC.

J Invest Dermatol. 2013 Oct;133(10):2362-71. doi: 10.1038/jid.2013.182. Epub 2013 Apr 17.

20.

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