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Items: 1 to 20 of 133

1.

Ganoderiol A-enriched extract suppresses migration and adhesion of MDA-MB-231 cells by inhibiting FAK-SRC-paxillin cascade pathway.

Wu GS, Song YL, Yin ZQ, Guo JJ, Wang SP, Zhao WW, Chen XP, Zhang QW, Lu JJ, Wang YT.

PLoS One. 2013 Oct 29;8(10):e76620. doi: 10.1371/journal.pone.0076620. eCollection 2013.

2.

Paxillin, a novel controller in the signaling of estrogen to FAK/N-WASP/Arp2/3 complex in breast cancer cells.

Shortrede JE, Uzair ID, Neira FJ, Flamini MI, Sanchez AM.

Mol Cell Endocrinol. 2016 Jul 15;430:56-67. doi: 10.1016/j.mce.2016.04.007. Epub 2016 Apr 16.

PMID:
27095481
3.

Inhibition of Src activation with cardiotoxin III blocks migration and invasion of MDA-MB-231 cells.

Tsai PC, Chu CL, Chiu CC, Chang LS, Lin SR.

Toxicon. 2013 Nov;74:56-67. doi: 10.1016/j.toxicon.2013.07.021. Epub 2013 Aug 7.

PMID:
23933586
4.

Retinoic acid induces nuclear FAK translocation and reduces breast cancer cell adhesion through Moesin, FAK, and Paxillin.

Sanchez AM, Shortrede JE, Vargas-Roig LM, Flamini MI.

Mol Cell Endocrinol. 2016 Jul 15;430:1-11. doi: 10.1016/j.mce.2016.04.021. Epub 2016 Apr 26.

PMID:
27130522
5.

Enterolactone alters FAK-Src signaling and suppresses migration and invasion of lung cancer cell lines.

Chikara S, Lindsey K, Borowicz P, Christofidou-Solomidou M, Reindl KM.

BMC Complement Altern Med. 2017 Jan 9;17(1):30. doi: 10.1186/s12906-016-1512-3.

6.

Human breast cancer cell metastasis is attenuated by lysyl oxidase inhibitors through down-regulation of focal adhesion kinase and the paxillin-signaling pathway.

Chen LC, Tu SH, Huang CS, Chen CS, Ho CT, Lin HW, Lee CH, Chang HW, Chang CH, Wu CH, Lee WS, Ho YS.

Breast Cancer Res Treat. 2012 Aug;134(3):989-1004. doi: 10.1007/s10549-012-1986-8. Epub 2012 Mar 21.

PMID:
22434522
7.

Arachidonic acid promotes FAK activation and migration in MDA-MB-231 breast cancer cells.

Navarro-Tito N, Robledo T, Salazar EP.

Exp Cell Res. 2008 Nov 1;314(18):3340-55. doi: 10.1016/j.yexcr.2008.08.018. Epub 2008 Sep 9.

PMID:
18804105
8.

Altering FAK-paxillin interactions reduces adhesion, migration and invasion processes.

Deramaudt TB, Dujardin D, Noulet F, Martin S, Vauchelles R, Takeda K, Rondé P.

PLoS One. 2014 Mar 18;9(3):e92059. doi: 10.1371/journal.pone.0092059. eCollection 2014.

9.
10.

Novel Small Molecule JP-153 Targets the Src-FAK-Paxillin Signaling Complex to Inhibit VEGF-Induced Retinal Angiogenesis.

Toutounchian JJ, Pagadala J, Miller DD, Baudry J, Park F, Chaum E, Yates CR.

Mol Pharmacol. 2017 Jan;91(1):1-13. Epub 2016 Nov 9. Erratum in: Mol Pharmacol. 2017 Dec;92 (6):627.

PMID:
27913654
11.
12.
13.

Estrogen stimulation of cell migration involves multiple signaling pathway interactions.

Li Y, Wang JP, Santen RJ, Kim TH, Park H, Fan P, Yue W.

Endocrinology. 2010 Nov;151(11):5146-56. doi: 10.1210/en.2009-1506. Epub 2010 Sep 22.

14.

Targeting the Metastasis Suppressor, N-Myc Downstream Regulated Gene-1, with Novel Di-2-Pyridylketone Thiosemicarbazones: Suppression of Tumor Cell Migration and Cell-Collagen Adhesion by Inhibiting Focal Adhesion Kinase/Paxillin Signaling.

Wangpu X, Lu J, Xi R, Yue F, Sahni S, Park KC, Menezes S, Huang ML, Zheng M, Kovacevic Z, Richardson DR.

Mol Pharmacol. 2016 May;89(5):521-40. doi: 10.1124/mol.115.103044. Epub 2016 Feb 19.

15.

Estrogen receptor-alpha promotes breast cancer cell motility and invasion via focal adhesion kinase and N-WASP.

Sanchez AM, Flamini MI, Baldacci C, Goglia L, Genazzani AR, Simoncini T.

Mol Endocrinol. 2010 Nov;24(11):2114-25. doi: 10.1210/me.2010-0252. Epub 2010 Sep 29.

16.

3-Hydroxyflavone inhibits human osteosarcoma U2OS and 143B cells metastasis by affecting EMT and repressing u-PA/MMP-2 via FAK-Src to MEK/ERK and RhoA/MLC2 pathways and reduces 143B tumor growth in vivo.

Lu KH, Chen PN, Hsieh YH, Lin CY, Cheng FY, Chiu PC, Chu SC, Hsieh YS.

Food Chem Toxicol. 2016 Nov;97:177-186. doi: 10.1016/j.fct.2016.09.006. Epub 2016 Sep 4.

PMID:
27600294
17.

CD151 mediates netrin-1-induced angiogenesis through the Src-FAK-Paxillin pathway.

Yang X, Li S, Zhong J, Zhang W, Hua X, Li B, Sun H.

J Cell Mol Med. 2017 Jan;21(1):72-80. doi: 10.1111/jcmm.12939. Epub 2016 Aug 25.

18.

ARF1 regulates adhesion of MDA-MB-231 invasive breast cancer cells through formation of focal adhesions.

Schlienger S, Ramirez RA, Claing A.

Cell Signal. 2015 Mar;27(3):403-15. doi: 10.1016/j.cellsig.2014.11.032. Epub 2014 Dec 19.

PMID:
25530216
19.

Glabridin inhibits migration, invasion, and angiogenesis of human non-small cell lung cancer A549 cells by inhibiting the FAK/rho signaling pathway.

Tsai YM, Yang CJ, Hsu YL, Wu LY, Tsai YC, Hung JY, Lien CT, Huang MS, Kuo PL.

Integr Cancer Ther. 2011 Dec;10(4):341-9. doi: 10.1177/1534735410384860. Epub 2010 Nov 8.

PMID:
21059620
20.

FAK alters invadopodia and focal adhesion composition and dynamics to regulate breast cancer invasion.

Chan KT, Cortesio CL, Huttenlocher A.

J Cell Biol. 2009 Apr 20;185(2):357-70. doi: 10.1083/jcb.200809110. Epub 2009 Apr 13.

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