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Items: 1 to 20 of 113

1.

Activation of the FGFR-STAT3 pathway in breast cancer cells induces a hyaluronan-rich microenvironment that licenses tumor formation.

Bohrer LR, Chuntova P, Bade LK, Beadnell TC, Leon RP, Brady NJ, Ryu Y, Goldberg JE, Schmechel SC, Koopmeiners JS, McCarthy JB, Schwertfeger KL.

Cancer Res. 2014 Jan 1;74(1):374-86. doi: 10.1158/0008-5472.CAN-13-2469. Epub 2013 Nov 6.

2.

Macrophages promote fibroblast growth factor receptor-driven tumor cell migration and invasion in a CXCR2-dependent manner.

Bohrer LR, Schwertfeger KL.

Mol Cancer Res. 2012 Oct;10(10):1294-305. doi: 10.1158/1541-7786.MCR-12-0275. Epub 2012 Aug 14.

3.

Inhibition of FGFR signaling by PD173074 improves antitumor immunity and impairs breast cancer metastasis.

Ye T, Wei X, Yin T, Xia Y, Li D, Shao B, Song X, He S, Luo M, Gao X, He Z, Luo C, Xiong Y, Wang N, Zeng J, Zhao L, Shen G, Xie Y, Yu L, Wei Y.

Breast Cancer Res Treat. 2014 Feb;143(3):435-46. doi: 10.1007/s10549-013-2829-y. Epub 2014 Jan 8.

PMID:
24398778
4.

FGFR signaling promotes the growth of triple-negative and basal-like breast cancer cell lines both in vitro and in vivo.

Sharpe R, Pearson A, Herrera-Abreu MT, Johnson D, Mackay A, Welti JC, Natrajan R, Reynolds AR, Reis-Filho JS, Ashworth A, Turner NC.

Clin Cancer Res. 2011 Aug 15;17(16):5275-86. doi: 10.1158/1078-0432.CCR-10-2727. Epub 2011 Jun 28.

5.

C-X-C motif chemokine 12/C-X-C chemokine receptor type 7 signaling regulates breast cancer growth and metastasis by modulating the tumor microenvironment.

Wani N, Nasser MW, Ahirwar DK, Zhao H, Miao Z, Shilo K, Ganju RK.

Breast Cancer Res. 2014 May 29;16(3):R54. doi: 10.1186/bcr3665.

6.

Embryonic stem cell preconditioned microenvironment suppresses tumorigenic properties in breast cancer.

He N, Feng G, Li Y, Xu Y, Xie X, Wang H, Wang Y, Ou L, Pei X, Liu N, Li Z.

Stem Cell Res Ther. 2016 Jul 27;7(1):95. doi: 10.1186/s13287-016-0360-x.

7.

Targeting fibroblast growth factor receptors blocks PI3K/AKT signaling, induces apoptosis, and impairs mammary tumor outgrowth and metastasis.

Dey JH, Bianchi F, Voshol J, Bonenfant D, Oakeley EJ, Hynes NE.

Cancer Res. 2010 May 15;70(10):4151-62. doi: 10.1158/0008-5472.CAN-09-4479. Epub 2010 May 11.

8.

Hyaluronan synthase 2 overexpression is correlated with the tumorigenesis and metastasis of human breast cancer.

Li P, Xiang T, Li H, Li Q, Yang B, Huang J, Zhang X, Shi Y, Tan J, Ren G.

Int J Clin Exp Pathol. 2015 Oct 1;8(10):12101-14. eCollection 2015.

9.
10.

Progesterone receptor induces ErbB-2 nuclear translocation to promote breast cancer growth via a novel transcriptional effect: ErbB-2 function as a coactivator of Stat3.

Béguelin W, Díaz Flaqué MC, Proietti CJ, Cayrol F, Rivas MA, Tkach M, Rosemblit C, Tocci JM, Charreau EH, Schillaci R, Elizalde PV.

Mol Cell Biol. 2010 Dec;30(23):5456-72. doi: 10.1128/MCB.00012-10. Epub 2010 Sep 27.

11.

Rationale for targeting fibroblast growth factor receptor signaling in breast cancer.

André F, Cortés J.

Breast Cancer Res Treat. 2015 Feb;150(1):1-8. doi: 10.1007/s10549-015-3301-y. Epub 2015 Feb 13. Review.

12.

Fibroblast growth factor receptor splice variants are stable markers of oncogenic transforming growth factor β1 signaling in metastatic breast cancers.

Wendt MK, Taylor MA, Schiemann BJ, Sossey-Alaoui K, Schiemann WP.

Breast Cancer Res. 2014 Mar 11;16(2):R24. doi: 10.1186/bcr3623.

13.

CD44 attenuates metastatic invasion during breast cancer progression.

Lopez JI, Camenisch TD, Stevens MV, Sands BJ, McDonald J, Schroeder JA.

Cancer Res. 2005 Aug 1;65(15):6755-63.

14.

Regulator of G protein signaling 6 is a novel suppressor of breast tumor initiation and progression.

Maity B, Stewart A, O'Malley Y, Askeland RW, Sugg SL, Fisher RA.

Carcinogenesis. 2013 Aug;34(8):1747-55. doi: 10.1093/carcin/bgt128. Epub 2013 Apr 18.

15.

Targeting FGFR with dovitinib (TKI258): preclinical and clinical data in breast cancer.

André F, Bachelot T, Campone M, Dalenc F, Perez-Garcia JM, Hurvitz SA, Turner N, Rugo H, Smith JW, Deudon S, Shi M, Zhang Y, Kay A, Porta DG, Yovine A, Baselga J.

Clin Cancer Res. 2013 Jul 1;19(13):3693-702. doi: 10.1158/1078-0432.CCR-13-0190. Epub 2013 May 8.

16.

Antisense-mediated suppression of hyaluronan synthase 2 inhibits the tumorigenesis and progression of breast cancer.

Udabage L, Brownlee GR, Waltham M, Blick T, Walker EC, Heldin P, Nilsson SK, Thompson EW, Brown TJ.

Cancer Res. 2005 Jul 15;65(14):6139-50.

17.
18.

Mammary gland specific expression of Brk/PTK6 promotes delayed involution and tumor formation associated with activation of p38 MAPK.

Lofgren KA, Ostrander JH, Housa D, Hubbard GK, Locatelli A, Bliss RL, Schwertfeger KL, Lange CA.

Breast Cancer Res. 2011 Sep 17;13(5):R89. doi: 10.1186/bcr2946.

19.

Activation of JAK2/STAT3 signaling by osteopontin promotes tumor growth in human breast cancer cells.

Behera R, Kumar V, Lohite K, Karnik S, Kundu GC.

Carcinogenesis. 2010 Feb;31(2):192-200. doi: 10.1093/carcin/bgp289. Epub 2009 Nov 19.

PMID:
19926637
20.

Interleukin-33/ST2 axis promotes epithelial cell transformation and breast tumorigenesis via upregulation of COT activity.

Kim JY, Lim SC, Kim G, Yun HJ, Ahn SG, Choi HS.

Oncogene. 2015 Sep 17;34(38):4928-38. doi: 10.1038/onc.2014.418. Epub 2014 Dec 22.

PMID:
25531326

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