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Items: 1 to 20 of 107

1.

Pharmacological characterization of a dopamine transporter ligand that functions as a cocaine antagonist.

Desai RI, Grandy DK, Lupica CR, Katz JL.

J Pharmacol Exp Ther. 2014 Jan;348(1):106-15. doi: 10.1124/jpet.113.208538. Epub 2013 Nov 5.

3.

σ Receptor Effects of N-Substituted Benztropine Analogs: Implications for Antagonism of Cocaine Self-Administration.

Hiranita T, Hong WC, Kopajtic T, Katz JL.

J Pharmacol Exp Ther. 2017 Jul;362(1):2-13. doi: 10.1124/jpet.117.241109. Epub 2017 Apr 25.

4.

Identification of a dopamine transporter ligand that blocks the stimulant effects of cocaine.

Desai RI, Kopajtic TA, Koffarnus M, Newman AH, Katz JL.

J Neurosci. 2005 Feb 23;25(8):1889-93.

5.

Dopamine transporter-dependent and -independent striatal binding of the benztropine analog JHW 007, a cocaine antagonist with low abuse liability.

Kopajtic TA, Liu Y, Surratt CK, Donovan DM, Newman AH, Katz JL.

J Pharmacol Exp Ther. 2010 Dec;335(3):703-14. doi: 10.1124/jpet.110.171629. Epub 2010 Sep 20.

6.

Dopamine transporter binding without cocaine-like behavioral effects: synthesis and evaluation of benztropine analogs alone and in combination with cocaine in rodents.

Katz JL, Agoston GE, Alling KL, Kline RH, Forster MJ, Woolverton WL, Kopajtic TA, Newman AH.

Psychopharmacology (Berl). 2001 Apr;154(4):362-74.

PMID:
11349389
7.

The dopamine uptake inhibitor 3 alpha-[bis(4'-fluorophenyl)metoxy]-tropane reduces cocaine-induced early-gene expression, locomotor activity, and conditioned reward.

Velázquez-Sánchez C, Ferragud A, Hernández-Rabaza V, Nácher A, Merino V, Cardá M, Murga J, Canales JJ.

Neuropsychopharmacology. 2009 Nov;34(12):2497-507. doi: 10.1038/npp.2009.78. Epub 2009 Jul 15.

8.

Effects of N-substituted analogs of benztropine: diminished cocaine-like effects in dopamine transporter ligands.

Katz JL, Kopajtic TA, Agoston GE, Newman AH.

J Pharmacol Exp Ther. 2004 May;309(2):650-60. Epub 2004 Jan 30.

9.

Behavioral and neurochemical effects of the dopamine transporter ligand 4-chlorobenztropine alone and in combination with cocaine in vivo.

Tolliver BK, Newman AH, Katz JL, Ho LB, Fox LM, Hsu K Jr, Berger SP.

J Pharmacol Exp Ther. 1999 Apr;289(1):110-22.

10.

Preclinical efficacy of N-substituted benztropine analogs as antagonists of methamphetamine self-administration in rats.

Hiranita T, Kohut SJ, Soto PL, Tanda G, Kopajtic TA, Katz JL.

J Pharmacol Exp Ther. 2014 Jan;348(1):174-91. doi: 10.1124/jpet.113.208264. Epub 2013 Nov 5.

11.

N-substituted benztropine analogs: selective dopamine transporter ligands with a fast onset of action and minimal cocaine-like behavioral effects.

Li SM, Kopajtic TA, O'Callaghan MJ, Agoston GE, Cao J, Newman AH, Katz JL.

J Pharmacol Exp Ther. 2011 Feb;336(2):575-85. doi: 10.1124/jpet.110.173260. Epub 2010 Nov 18.

12.

Place conditioning and locomotor effects of N-substituted, 4',4''-difluorobenztropine analogs in rats.

Li SM, Newman AH, Katz JL.

J Pharmacol Exp Ther. 2005 Jun;313(3):1223-30. Epub 2005 Mar 2.

13.

Decreases in cocaine self-administration with dual inhibition of the dopamine transporter and σ receptors.

Hiranita T, Soto PL, Kohut SJ, Kopajtic T, Cao J, Newman AH, Tanda G, Katz JL.

J Pharmacol Exp Ther. 2011 Nov;339(2):662-77. doi: 10.1124/jpet.111.185025. Epub 2011 Aug 22.

15.

2-isoxazol-3-phenyltropane derivatives of cocaine: molecular and atypical system effects at the dopamine transporter.

Hiranita T, Wilkinson DS, Hong WC, Zou MF, Kopajtic TA, Soto PL, Lupica CR, Newman AH, Katz JL.

J Pharmacol Exp Ther. 2014 May;349(2):297-309. doi: 10.1124/jpet.113.212738. Epub 2014 Feb 11. Erratum in: J Pharmacol Exp Ther. 2014 Jun 1;349(3):534.

16.

Interaction of cocaine-, benztropine-, and GBR12909-like compounds with wild-type and mutant human dopamine transporters: molecular features that differentially determine antagonist-binding properties.

Schmitt KC, Zhen J, Kharkar P, Mishra M, Chen N, Dutta AK, Reith ME.

J Neurochem. 2008 Nov;107(4):928-40. doi: 10.1111/j.1471-4159.2008.05667.x. Epub 2008 Sep 11. Erratum in: J Neurochem. 2010 Oct;115(1):296.

17.

Evidence for the involvement of dopamine transporters in behavioral stimulant effects of modafinil.

Zolkowska D, Jain R, Rothman RB, Partilla JS, Roth BL, Setola V, Prisinzano TE, Baumann MH.

J Pharmacol Exp Ther. 2009 May;329(2):738-46. doi: 10.1124/jpet.108.146142. Epub 2009 Feb 5.

18.

Novel C-1 substituted cocaine analogs unlike cocaine or benztropine.

Reith ME, Ali S, Hashim A, Sheikh IS, Theddu N, Gaddiraju NV, Mehrotra S, Schmitt KC, Murray TF, Sershen H, Unterwald EM, Davis FA.

J Pharmacol Exp Ther. 2012 Nov;343(2):413-25. doi: 10.1124/jpet.112.193771. Epub 2012 Aug 15.

19.
20.

Assessment of reinforcing effects of benztropine analogs and their effects on cocaine self-administration in rats: comparisons with monoamine uptake inhibitors.

Hiranita T, Soto PL, Newman AH, Katz JL.

J Pharmacol Exp Ther. 2009 May;329(2):677-86. doi: 10.1124/jpet.108.145813. Epub 2009 Feb 19.

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