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PAX3 in neuroblastoma: oncogenic potential, chemosensitivity and signalling pathways.

Fang WH, Wang Q, Li HM, Ahmed M, Kumar P, Kumar S.

J Cell Mol Med. 2014 Jan;18(1):38-48. doi: 10.1111/jcmm.12155. Epub 2013 Nov 4.


Transcriptome analyses based on genetic screens for Pax3 myogenic targets in the mouse embryo.

Lagha M, Sato T, Regnault B, Cumano A, Zuniga A, Licht J, Relaix F, Buckingham M.

BMC Genomics. 2010 Dec 8;11:696. doi: 10.1186/1471-2164-11-696.


Panobinostat synergistically enhances the cytotoxic effects of cisplatin, doxorubicin or etoposide on high-risk neuroblastoma cells.

Wang G, Edwards H, Caldwell JT, Buck SA, Qing WY, Taub JW, Ge Y, Wang Z.

PLoS One. 2013 Sep 30;8(9):e76662. doi: 10.1371/journal.pone.0076662. eCollection 2013.


Regulation of target genes of PAX3-FOXO1 in alveolar rhabdomyosarcoma.

Ahn EH.

Anticancer Res. 2013 May;33(5):2029-35.


PAX3 promotes tumor progression via CD105 signaling.

Fang WH, Ahmed M, Wang Q, Li HM, Kumar P, Kumar S.

Microvasc Res. 2013 Mar;86:42-3. doi: 10.1016/j.mvr.2012.12.005. Epub 2012 Dec 26. No abstract available.


The development of cisplatin resistance in neuroblastoma is accompanied by epithelial to mesenchymal transition in vitro.

Piskareva O, Harvey H, Nolan J, Conlon R, Alcock L, Buckley P, Dowling P, Henry M, O'Sullivan F, Bray I, Stallings RL.

Cancer Lett. 2015 Aug 10;364(2):142-55. doi: 10.1016/j.canlet.2015.05.004. Epub 2015 May 7. Erratum in: Cancer Lett. 2015 Dec 28;369(2):428. Henry, Michael [added].


GSK-3 promotes cell survival, growth, and PAX3 levels in human melanoma cells.

Kubic JD, Mascarenhas JB, Iizuka T, Wolfgeher D, Lang D.

Mol Cancer Res. 2012 Aug;10(8):1065-76. doi: 10.1158/1541-7786.MCR-11-0387. Epub 2012 Jun 7.


Reciprocal potentiation of the antitumoral activities of FK866, an inhibitor of nicotinamide phosphoribosyltransferase, and etoposide or cisplatin in neuroblastoma cells.

Travelli C, Drago V, Maldi E, Kaludercic N, Galli U, Boldorini R, Di Lisa F, Tron GC, Canonico PL, Genazzani AA.

J Pharmacol Exp Ther. 2011 Sep;338(3):829-40. doi: 10.1124/jpet.111.184630. Epub 2011 Jun 17.


PAX3 knockdown in metastatic melanoma cell lines does not reduce MITF expression.

He S, Li CG, Slobbe L, Glover A, Marshall E, Baguley BC, Eccles MR.

Melanoma Res. 2011 Feb;21(1):24-34. doi: 10.1097/CMR.0b013e328341c7e0.


[The effect of Bcl-2 gene silencing on the sensitivity of cell line A549 to chemotherapeutic drugs].

Wang JQ, Du ZW, Gao XF, Wu M, Zhang YC, Pan Y, Wang Q, Zhang GZ.

Zhonghua Jie He He Hu Xi Za Zhi. 2013 Mar;36(3):191-7. Chinese.


P-cadherin is a direct PAX3-FOXO1A target involved in alveolar rhabdomyosarcoma aggressiveness.

Thuault S, Hayashi S, Lagirand-Cantaloube J, Plutoni C, Comunale F, Delattre O, Relaix F, Gauthier-Rouvière C.

Oncogene. 2013 Apr 11;32(15):1876-87. doi: 10.1038/onc.2012.217. Epub 2012 Jun 18.


Mechanisms contributing to differential regulation of PAX3 downstream target genes in normal human epidermal melanocytes versus melanoma cells.

Bartlett D, Boyle GM, Ziman M, Medic S.

PLoS One. 2015 Apr 16;10(4):e0124154. doi: 10.1371/journal.pone.0124154. eCollection 2015.


Transfection of melanoma cells with antisense PAX3 oligonucleotides additively complements cisplatin-induced cytotoxicity.

He SJ, Stevens G, Braithwaite AW, Eccles MR.

Mol Cancer Ther. 2005 Jun;4(6):996-1003.


MDM2 mediated nuclear exclusion of p53 attenuates etoposide-induced apoptosis in neuroblastoma cells.

Rodriguez-Lopez AM, Xenaki D, Eden TO, Hickman JA, Chresta CM.

Mol Pharmacol. 2001 Jan;59(1):135-43.


Slug (SNAI2) down-regulation by RNA interference facilitates apoptosis and inhibits invasive growth in neuroblastoma preclinical models.

Vitali R, Mancini C, Cesi V, Tanno B, Mancuso M, Bossi G, Zhang Y, Martinez RV, Calabretta B, Dominici C, Raschellà G.

Clin Cancer Res. 2008 Jul 15;14(14):4622-30. doi: 10.1158/1078-0432.CCR-07-5210.


PAX3 is overexpressed in human glioblastomas and critically regulates the tumorigenicity of glioma cells.

Xia L, Huang Q, Nie D, Shi J, Gong M, Wu B, Gong P, Zhao L, Zuo H, Ju S, Chen J, Shi W.

Brain Res. 2013 Jul 12;1521:68-78. doi: 10.1016/j.brainres.2013.05.021. Epub 2013 May 20.


MicroRNA-497 increases apoptosis in MYCN amplified neuroblastoma cells by targeting the key cell cycle regulator WEE1.

Creevey L, Ryan J, Harvey H, Bray IM, Meehan M, Khan AR, Stallings RL.

Mol Cancer. 2013 Mar 26;12:23. doi: 10.1186/1476-4598-12-23.


Knockdown of astrocyte elevated gene-1 inhibits proliferation and enhancing chemo-sensitivity to cisplatin or doxorubicin in neuroblastoma cells.

Liu H, Song X, Liu C, Xie L, Wei L, Sun R.

J Exp Clin Cancer Res. 2009 Feb 15;28:19. doi: 10.1186/1756-9966-28-19.

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