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Items: 1 to 20 of 84

1.

Binding potential of (E)-[¹¹C]ABP688 to metabotropic glutamate receptor subtype 5 is decreased by the inclusion of its ¹¹C-labelled Z-isomer.

Kawamura K, Yamasaki T, Kumata K, Furutsuka K, Takei M, Wakizaka H, Fujinaga M, Kariya K, Yui J, Hatori A, Xie L, Shimoda Y, Hashimoto H, Hayashi K, Zhang MR.

Nucl Med Biol. 2014 Jan;41(1):17-23. doi: 10.1016/j.nucmedbio.2013.09.008. Epub 2013 Oct 8.

PMID:
24183615
2.

N-acetylcysteine- and MK-801-induced changes in glutamate levels do not affect in vivo binding of metabotropic glutamate 5 receptor radioligand 11C-ABP688 in rat brain.

Wyckhuys T, Verhaeghe J, Wyffels L, Langlois X, Schmidt M, Stroobants S, Staelens S.

J Nucl Med. 2013 Nov;54(11):1954-61. doi: 10.2967/jnumed.113.121608. Epub 2013 Sep 19.

3.

Synthesis, radiolabeling, in vitro and in vivo evaluation of [18F]-FPECMO as a positron emission tomography radioligand for imaging the metabotropic glutamate receptor subtype 5.

Lucatelli C, Honer M, Salazar JF, Ross TL, Schubiger PA, Ametamey SM.

Nucl Med Biol. 2009 Aug;36(6):613-22. doi: 10.1016/j.nucmedbio.2009.03.005.

PMID:
19647167
5.

Radiosynthesis and preclinical evaluation of 11C-ABP688 as a probe for imaging the metabotropic glutamate receptor subtype 5.

Ametamey SM, Kessler LJ, Honer M, Wyss MT, Buck A, Hintermann S, Auberson YP, Gasparini F, Schubiger PA.

J Nucl Med. 2006 Apr;47(4):698-705.

6.

Human PET studies of metabotropic glutamate receptor subtype 5 with 11C-ABP688.

Ametamey SM, Treyer V, Streffer J, Wyss MT, Schmidt M, Blagoev M, Hintermann S, Auberson Y, Gasparini F, Fischer UC, Buck A.

J Nucl Med. 2007 Feb;48(2):247-52.

7.

In vitro and in vivo evaluation of [18F]-FDEGPECO as a PET tracer for imaging the metabotropic glutamate receptor subtype 5 (mGluR5).

Wanger-Baumann CA, Mu L, Honer M, Belli S, Alf MF, Schubiger PA, Krämer SD, Ametamey SM.

Neuroimage. 2011 Jun 1;56(3):984-91. doi: 10.1016/j.neuroimage.2011.03.024. Epub 2011 Mar 21.

PMID:
21406237
8.

Synthesis and evaluation of novel α-fluorinated (E)-3-((6-methylpyridin-2-yl)ethynyl)cyclohex-2-enone-O-methyl oxime (ABP688) derivatives as metabotropic glutamate receptor subtype 5 PET radiotracers.

Milicevic Sephton S, Mu L, Schweizer WB, Schibli R, Krämer SD, Ametamey SM.

J Med Chem. 2012 Aug 23;55(16):7154-62. doi: 10.1021/jm300648b. Epub 2012 Aug 9.

PMID:
22822714
9.

Characterization of age/sex and the regional distribution of mGluR5 availability in the healthy human brain measured by high-resolution [(11)C]ABP688 PET.

DuBois JM, Rousset OG, Rowley J, Porras-Betancourt M, Reader AJ, Labbe A, Massarweh G, Soucy JP, Rosa-Neto P, Kobayashi E.

Eur J Nucl Med Mol Imaging. 2016 Jan;43(1):152-62. doi: 10.1007/s00259-015-3167-6. Epub 2015 Aug 21.

PMID:
26290423
10.

In vivo ketamine-induced changes in [¹¹C]ABP688 binding to metabotropic glutamate receptor subtype 5.

DeLorenzo C, DellaGioia N, Bloch M, Sanacora G, Nabulsi N, Abdallah C, Yang J, Wen R, Mann JJ, Krystal JH, Parsey RV, Carson RE, Esterlis I.

Biol Psychiatry. 2015 Feb 1;77(3):266-75. doi: 10.1016/j.biopsych.2014.06.024. Epub 2014 Jul 10.

11.

Quantitative evaluation of 11C-ABP688 as PET ligand for the measurement of the metabotropic glutamate receptor subtype 5 using autoradiographic studies and a beta-scintillator.

Wyss MT, Ametamey SM, Treyer V, Bettio A, Blagoev M, Kessler LJ, Burger C, Weber B, Schmidt M, Gasparini F, Buck A.

Neuroimage. 2007 Apr 15;35(3):1086-92. Epub 2007 Jan 24.

PMID:
17320417
12.

Radiolabeling and in vitro and in vivo evaluation of [18F]-FE-DABP688 as a PET radioligand for the metabotropic glutamate receptor subtype 5.

Honer M, Stoffel A, Kessler LJ, Schubiger PA, Ametamey SM.

Nucl Med Biol. 2007 Nov;34(8):973-80. Epub 2007 Sep 19.

PMID:
17998101
13.

Preclinical evaluation and test-retest studies of [(18)F]PSS232, a novel radioligand for targeting metabotropic glutamate receptor 5 (mGlu5).

Sephton SM, Herde AM, Mu L, Keller C, Rüdisühli S, Auberson Y, Schibli R, Krämer SD, Ametamey SM.

Eur J Nucl Med Mol Imaging. 2015 Jan;42(1):128-37. doi: 10.1007/s00259-014-2883-7. Epub 2014 Aug 20.

PMID:
25139517
14.

In vivo variation in metabotropic glutamate receptor subtype 5 binding using positron emission tomography and [11C]ABP688.

DeLorenzo C, Kumar JS, Mann JJ, Parsey RV.

J Cereb Blood Flow Metab. 2011 Nov;31(11):2169-80. doi: 10.1038/jcbfm.2011.105. Epub 2011 Jul 27.

15.

In vivo and in vitro validation of reference tissue models for the mGluR(5) ligand [(11)C]ABP688.

Elmenhorst D, Minuzzi L, Aliaga A, Rowley J, Massarweh G, Diksic M, Bauer A, Rosa-Neto P.

J Cereb Blood Flow Metab. 2010 Aug;30(8):1538-49. doi: 10.1038/jcbfm.2010.65. Epub 2010 Jun 9.

16.

In vivo positron emission tomography imaging with [¹¹C]ABP688: binding variability and specificity for the metabotropic glutamate receptor subtype 5 in baboons.

DeLorenzo C, Milak MS, Brennan KG, Kumar JS, Mann JJ, Parsey RV.

Eur J Nucl Med Mol Imaging. 2011 Jun;38(6):1083-94. doi: 10.1007/s00259-010-1723-7. Epub 2011 Jan 29.

17.

Imaging glutamate homeostasis in cocaine addiction with the metabotropic glutamate receptor 5 positron emission tomography radiotracer [(11)C]ABP688 and magnetic resonance spectroscopy.

Martinez D, Slifstein M, Nabulsi N, Grassetti A, Urban NB, Perez A, Liu F, Lin SF, Ropchan J, Mao X, Kegeles LS, Shungu DC, Carson RE, Huang Y.

Biol Psychiatry. 2014 Jan 15;75(2):165-71. doi: 10.1016/j.biopsych.2013.06.026. Epub 2013 Sep 12.

18.

In vitro and in vivo evaluation of [11C]MPEPy as a potential PET ligand for mGlu5 receptors.

Severance AJ, Parsey RV, Kumar JS, Underwood MD, Arango V, Majo VJ, Prabhakaran J, Simpson NR, Van Heertum RL, Mann JJ.

Nucl Med Biol. 2006 Nov;33(8):1021-7.

PMID:
17127176
19.

Development of [(18)F]-PSS223 as a PET tracer for imaging of metabotropic glutamate receptor subtype 5 (mGluR5).

Sephton SM, Dennler P, Leutwiler DS, Mu L, Schibli R, Krämer SD, Ametamey SM.

Chimia (Aarau). 2012;66(4):201-4. doi: 10.2533/chimia.2012.201.

PMID:
22613149
20.

In vivo imaging of mGluR5 changes during epileptogenesis using [11C]ABP688 PET in pilocarpine-induced epilepsy rat model.

Choi H, Kim YK, Oh SW, Im HJ, Hwang DW, Kang H, Lee B, Lee YS, Jeong JM, Kim EE, Chung JK, Lee DS.

PLoS One. 2014 Mar 24;9(3):e92765. doi: 10.1371/journal.pone.0092765. eCollection 2014.

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