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Items: 1 to 20 of 64


A cellular genome-wide association study reveals human variation in microtubule stability and a role in inflammatory cell death.

Salinas RE, Ogohara C, Thomas MI, Shukla KP, Miller SI, Ko DC.

Mol Biol Cell. 2014 Jan;25(1):76-86. doi: 10.1091/mbc.E13-06-0294. Epub 2013 Oct 30.


Molecular basis for class V beta-tubulin effects on microtubule assembly and paclitaxel resistance.

Bhattacharya R, Cabral F.

J Biol Chem. 2009 May 8;284(19):13023-32. doi: 10.1074/jbc.M900167200. Epub 2009 Mar 12.


β-1 tubulin R307H SNP alters microtubule dynamics and affects severity of a hereditary thrombocytopenia.

Basciano PA, Matakas J, Pecci A, Civaschi E, Cagioni C, Bompiani N, Burger P, Christos P, Snyder JP, Bussel J, Balduini CL, Giannakakou P, Noris P.

J Thromb Haemost. 2015 Apr;13(4):651-9. doi: 10.1111/jth.12824. Epub 2015 Jan 22.


Expression of recombinant alpha and beta tubulins from the yew Taxus cuspidata and analysis of the microtubule assembly in the presence of taxol.

Kudo Y, Abe A, Ito K, Cho Y, Yotsu-Yamashita M, Konoki K.

Biosci Biotechnol Biochem. 2014;78(11):1887-94. doi: 10.1080/09168451.2014.940837. Epub 2014 Jul 29.


BetaIII-tubulin induces paclitaxel resistance in association with reduced effects on microtubule dynamic instability.

Kamath K, Wilson L, Cabral F, Jordan MA.

J Biol Chem. 2005 Apr 1;280(13):12902-7. Epub 2005 Feb 6.


Microtubule dynamics, mitotic arrest, and apoptosis: drug-induced differential effects of betaIII-tubulin.

Gan PP, McCarroll JA, Po'uha ST, Kamath K, Jordan MA, Kavallaris M.

Mol Cancer Ther. 2010 May;9(5):1339-48. doi: 10.1158/1535-7163.MCT-09-0679. Epub 2010 May 4.


Modulating microtubule stability enhances the cytotoxic response of cancer cells to Paclitaxel.

Ahmed AA, Wang X, Lu Z, Goldsmith J, Le XF, Grandjean G, Bartholomeusz G, Broom B, Bast RC Jr.

Cancer Res. 2011 Sep 1;71(17):5806-17. doi: 10.1158/0008-5472.CAN-11-0025. Epub 2011 Jul 20.


Gasdermin D is an executor of pyroptosis and required for interleukin-1β secretion.

He WT, Wan H, Hu L, Chen P, Wang X, Huang Z, Yang ZH, Zhong CQ, Han J.

Cell Res. 2015 Dec;25(12):1285-98. doi: 10.1038/cr.2015.139. Epub 2015 Nov 27.


Dissecting paclitaxel-microtubule association: quantitative assessment of the 2'-OH group.

Sharma S, Lagisetti C, Poliks B, Coates RM, Kingston DG, Bane S.

Biochemistry. 2013 Apr 2;52(13):2328-36. doi: 10.1021/bi400014t. Epub 2013 Mar 19.


Amino acid substitutions at proline 220 of beta-tubulin confer resistance to paclitaxel and colcemid.

Yin S, Cabral F, Veeraraghavan S.

Mol Cancer Ther. 2007 Oct;6(10):2798-806.


Cellular studies reveal mechanistic differences between taccalonolide A and paclitaxel.

Risinger AL, Mooberry SL.

Cell Cycle. 2011 Jul 1;10(13):2162-71. Epub 2011 Jul 1.


Survivin counteracts the therapeutic effect of microtubule de-stabilizers by stabilizing tubulin polymers.

Cheung CH, Chen HH, Kuo CC, Chang CY, Coumar MS, Hsieh HP, Chang JY.

Mol Cancer. 2009 Jul 3;8:43. doi: 10.1186/1476-4598-8-43.


Highly dynamic microtubules improve the effectiveness of early stages of human influenza A/NWS/33 virus infection in LLC-MK2 cells.

De Conto F, Di Lonardo E, Arcangeletti MC, Chezzi C, Medici MC, Calderaro A.

PLoS One. 2012;7(7):e41207. doi: 10.1371/journal.pone.0041207. Epub 2012 Jul 20.


Isolation of microtubules and microtubule-associated proteins using Paclitaxel.

Sloboda RD.

Cold Spring Harb Protoc. 2015 Jan 5;2015(1):pdb.prot081190. doi: 10.1101/pdb.prot081190.


Microtubule-interacting drugs induce moderate and reversible damage to human bone marrow mesenchymal stem cells.

Polioudaki H, Kastrinaki MC, Papadaki HA, Theodoropoulos PA.

Cell Prolif. 2009 Aug;42(4):434-47. doi: 10.1111/j.1365-2184.2009.00607.x. Epub 2009 May 22.


Identification of a new microtubule-interacting protein Mip-90.

González M, Cambiazo V, Maccioni RB.

Eur J Cell Biol. 1995 Jun;67(2):158-69.


Sequestration of free tubulin molecules by the viral protein NSP2 induces microtubule depolymerization during rotavirus infection.

Martin D, Duarte M, Lepault J, Poncet D.

J Virol. 2010 Mar;84(5):2522-32. doi: 10.1128/JVI.01883-09. Epub 2009 Dec 23.

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