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SC35 promotes splicing of the C5-V6-C6 isoform of CD44 pre-mRNA.

Loh TJ, Moon H, Cho S, Jung DW, Hong SE, Kim DH, Green MR, Zheng X, Zhou J, Shen H.

Oncol Rep. 2014 Jan;31(1):273-9. doi: 10.3892/or.2013.2812.


SR proteins regulate V6 exon splicing of CD44 pre-mRNA.

Loh TJ, Moon H, Jang HN, Liu Y, Choi N, Shen S, Williams DR, Jung DW, Zheng X, Shen H.

BMB Rep. 2016 Nov;49(11):612-616.


CD44 alternative splicing and hnRNP A1 expression are associated with the metastasis of breast cancer.

Loh TJ, Moon H, Cho S, Jang H, Liu YC, Tai H, Jung DW, Williams DR, Kim HR, Shin MG, Liao DJ, Zhou J, Shi W, Zheng X, Shen H.

Oncol Rep. 2015 Sep;34(3):1231-8. doi: 10.3892/or.2015.4110.


Vitamin A metabolite, all-trans-retinoic acid, mediates alternative splicing of protein kinase C deltaVIII (PKCdeltaVIII) isoform via splicing factor SC35.

Apostolatos H, Apostolatos A, Vickers T, Watson JE, Song S, Vale F, Cooper DR, Sanchez-Ramos J, Patel NA.

J Biol Chem. 2010 Aug 20;285(34):25987-95. doi: 10.1074/jbc.M110.100735.


Nuclear Speckle-related Protein 70 Binds to Serine/Arginine-rich Splicing Factors 1 and 2 via an Arginine/Serine-like Region and Counteracts Their Alternative Splicing Activity.

Kim CH, Kim YD, Choi EK, Kim HR, Na BR, Im SH, Jun CD.

J Biol Chem. 2016 Mar 18;291(12):6169-81. doi: 10.1074/jbc.M115.689414.


Oxidative stress-induced alternative splicing of transformer 2beta (SFRS10) and CD44 pre-mRNAs in gastric epithelial cells.

Takeo K, Kawai T, Nishida K, Masuda K, Teshima-Kondo S, Tanahashi T, Rokutan K.

Am J Physiol Cell Physiol. 2009 Aug;297(2):C330-8. doi: 10.1152/ajpcell.00009.2009.


SC35 autoregulates its expression by promoting splicing events that destabilize its mRNAs.

Sureau A, Gattoni R, Dooghe Y, Stévenin J, Soret J.

EMBO J. 2001 Apr 2;20(7):1785-96.


Regulation of the alternative splicing of tau exon 10 by SC35 and Dyrk1A.

Qian W, Liang H, Shi J, Jin N, Grundke-Iqbal I, Iqbal K, Gong CX, Liu F.

Nucleic Acids Res. 2011 Aug;39(14):6161-71. doi: 10.1093/nar/gkr195.


Downregulation of splicing factor SRSF3 induces p53β, an alternatively spliced isoform of p53 that promotes cellular senescence.

Tang Y, Horikawa I, Ajiro M, Robles AI, Fujita K, Mondal AM, Stauffer JK, Zheng ZM, Harris CC.

Oncogene. 2013 May 30;32(22):2792-8. doi: 10.1038/onc.2012.288.


Splicing factor Tra2-beta1 is specifically induced in breast cancer and regulates alternative splicing of the CD44 gene.

Watermann DO, Tang Y, Zur Hausen A, Jäger M, Stamm S, Stickeler E.

Cancer Res. 2006 May 1;66(9):4774-80.


hnRNP L inhibits CD44 V10 exon splicing through interacting with its upstream intron.

Loh TJ, Cho S, Moon H, Jang HN, Williams DR, Jung DW, Kim IC, Ghigna C, Biamonti G, Zheng X, Shen H.

Biochim Biophys Acta. 2015 Jun;1849(6):743-50. doi: 10.1016/j.bbagrm.2015.01.004.


Expression of antisense CD44 variant 6 inhibits colorectal tumor metastasis and tumor growth in a wound environment.

Reeder JA, Gotley DC, Walsh MD, Fawcett J, Antalis TM.

Cancer Res. 1998 Aug 15;58(16):3719-26.


CD44 splicing pattern is associated with disease progression in pulmonary adenocarcinoma.

Lee LN, Kuo SH, Lee YC, Chang YL, Chang HC, Jan IS, Yang PC.

J Formos Med Assoc. 2005 Aug;104(8):541-8.


Splicing factor SC35 promotes tau expression through stabilization of its mRNA.

Qian W, Iqbal K, Grundke-Iqbal I, Gong CX, Liu F.

FEBS Lett. 2011 Mar 23;585(6):875-80. doi: 10.1016/j.febslet.2011.02.017.


Expression of exon v6-containing CD44 isoforms is related to poor prognosis of acute myelocytic leukemia.

Yokota A, Ishii G, Sugaya Y, Nishimura M, Saito Y, Harigaya K.

Hematol Oncol. 1998 Dec;16(4):131-41.


The role of alternative splicing of the adhesion molecule, CD44, in lymphoid malignancy.

Irving JA, Cain G, Howard M, Angus B, Taylor PR, Cattan AR.

J Clin Pathol. 1998 Oct;51(10):776-80.


De novo expression of CD44 variants in sporadic and hereditary gastric cancer.

da Cunha CB, Oliveira C, Wen X, Gomes B, Sousa S, Suriano G, Grellier M, Huntsman DG, Carneiro F, Granja PL, Seruca R.

Lab Invest. 2010 Nov;90(11):1604-14. doi: 10.1038/labinvest.2010.155.


Distinct CD44 splice variants differentially affect collateral artery growth.

Bot PT, Grundmann S, van Royen N, Joosten SP, Schirmer SH, de Kleijn DP, Pals ST, Pasterkamp G, Piek JJ, Hoefer IE.

Curr Vasc Pharmacol. 2013 Jan;11(1):13-20.


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