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Items: 1 to 20 of 81

1.

Effective utilization and appropriate selection of genetically engineered mouse models for translational integration of mouse and human trials.

Abate-Shen C, Pandolfi PP.

Cold Spring Harb Protoc. 2013 Nov 1;2013(11). pii: pdb.top078774. doi: 10.1101/pdb.top078774.

2.

Infrastructure needs for translational integration of mouse and human trials.

Clohessy JG, de Stanchina E.

Cold Spring Harb Protoc. 2013 Dec 1;2013(12):1109-14. doi: 10.1101/pdb.top078782.

PMID:
24173312
3.

A co-clinical platform to accelerate cancer treatment optimization.

Lunardi A, Pandolfi PP.

Trends Mol Med. 2015 Jan;21(1):1-5. doi: 10.1016/j.molmed.2014.10.008. Epub 2014 Nov 17.

PMID:
25466492
4.

Genetically engineered mouse models in oncology research and cancer medicine.

Kersten K, de Visser KE, van Miltenburg MH, Jonkers J.

EMBO Mol Med. 2017 Feb;9(2):137-153. doi: 10.15252/emmm.201606857. Review.

5.

Translational therapeutics in genetically engineered mouse models of cancer.

Olive KP, Politi K.

Cold Spring Harb Protoc. 2014 Feb 1;2014(2):131-43. doi: 10.1101/pdb.top069997.

PMID:
24492770
6.

Overview of Genetically Engineered Mouse Models of Distinct Breast Cancer Subtypes.

Usary J, Darr DB, Pfefferle AD, Perou CM.

Curr Protoc Pharmacol. 2016 Mar 18;72:14.38.1-11. doi: 10.1002/0471141755.ph1438s72. Review.

7.

One mouse, one patient paradigm: New avatars of personalized cancer therapy.

Malaney P, Nicosia SV, Davé V.

Cancer Lett. 2014 Mar 1;344(1):1-12. doi: 10.1016/j.canlet.2013.10.010. Epub 2013 Oct 22. Review.

8.

From mice to men: GEMMs as trial patients for new NSCLC therapies.

Hayes SA, Hudson AL, Clarke SJ, Molloy MP, Howell VM.

Semin Cell Dev Biol. 2014 Mar;27:118-27. doi: 10.1016/j.semcdb.2014.04.002. Epub 2014 Apr 6. Review.

PMID:
24718320
9.

Priceless GEMMs: genetically engineered mouse models for colorectal cancer drug development.

Roper J, Hung KE.

Trends Pharmacol Sci. 2012 Aug;33(8):449-55. doi: 10.1016/j.tips.2012.05.001. Epub 2012 Jun 26. Review.

PMID:
22739258
10.

Rapid validation of cancer genes in chimeras derived from established genetically engineered mouse models.

Huijbers IJ, Krimpenfort P, Berns A, Jonkers J.

Bioessays. 2011 Sep;33(9):701-10. doi: 10.1002/bies.201100018. Epub 2011 Jul 7.

11.

Predictive in vivo animal models and translation to clinical trials.

Cook N, Jodrell DI, Tuveson DA.

Drug Discov Today. 2012 Mar;17(5-6):253-60. Review.

PMID:
22493784
12.

Non-germline genetically engineered mouse models for translational cancer research.

Heyer J, Kwong LN, Lowe SW, Chin L.

Nat Rev Cancer. 2010 Jul;10(7):470-80. doi: 10.1038/nrc2877. Review.

13.

Genetically engineered cancer models, but not xenografts, faithfully predict anticancer drug exposure in melanoma tumors.

Combest AJ, Roberts PJ, Dillon PM, Sandison K, Hanna SK, Ross C, Habibi S, Zamboni B, Müller M, Brunner M, Sharpless NE, Zamboni WC.

Oncologist. 2012;17(10):1303-16. doi: 10.1634/theoncologist.2012-0274. Epub 2012 Sep 19.

14.

The promise of genetically engineered mice for cancer prevention studies.

Green JE, Hudson T.

Nat Rev Cancer. 2005 Mar;5(3):184-98. Review.

PMID:
15738982
15.

From bedding to bedside: genetically engineered mouse models of cancer inform concurrent clinical trials.

Damsky WE, Bosenberg M.

Pigment Cell Melanoma Res. 2012 Jul;25(4):404-5. doi: 10.1111/j.1755-148X.2012.01013.x. No abstract available.

PMID:
22578163
16.

Spontaneous and genetically engineered animal models; use in preclinical cancer drug development.

Hansen K, Khanna C.

Eur J Cancer. 2004 Apr;40(6):858-80. Review.

PMID:
15120042
17.

Genetically engineered mouse models of brain cancer and the promise of preclinical testing.

Huse JT, Holland EC.

Brain Pathol. 2009 Jan;19(1):132-43. doi: 10.1111/j.1750-3639.2008.00234.x. Review.

18.

Preclinical and Coclinical Studies in Prostate Cancer.

Chen M, Pandolfi PP.

Cold Spring Harb Perspect Med. 2017 Oct 16. pii: a030544. doi: 10.1101/cshperspect.a030544. [Epub ahead of print]

PMID:
29038335
19.

Overview of genetically engineered mouse models of colorectal carcinoma to enable translational biology and drug development.

Roper J, Martin ES, Hung KE.

Curr Protoc Pharmacol. 2014 Jun 16;65:14.29.1-10. doi: 10.1002/0471141755.ph1429s65.

PMID:
24934606
20.

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